Biochemistry News and Research

RSS

Nitric oxide could one day help women in their 30s and 40s remain fertile longer

Researchers have found that an important chemical compound, nitric oxide, appears to slow or reverse the aging of eggs in mouse ovaries. The finding suggests nitric oxide could one day help women in their 30s and 40s remain fertile longer and increase their chances of having healthy babies, the scientists say.

7 Sep 2005

Collaborators seek parasite invasion blockers

A malaria research team, including WEHI Structural Biologist, Professor Ray Norton, has received a US$1 million grant from the US National Institutes of Health to develop more effective malaria treatments.

7 Sep 2005

Diet rich in soy protein may alleviate fatty liver

A group of researchers from Mexico has discovered that a diet rich in soy protein may alleviate fatty liver, a disease which often accompanies diabetes. The details of their findings appear in the September issue of the Journal of Lipid Research, an American Society for Biochemistry and Molecular Biology journal.

6 Sep 2005

Potential new way to fight HIV

Researchers have confirmed for the first time the benefit of an innate defense system present in the few patients who remain healthy after years of infection with HIV despite receiving no treatment, according to an article published in the September edition of the Journal of Virology.

1 Sep 2005

Study points to link to neurodegenerative disease target

A University of California - San Francisco (UCSF) study has found that a specific signaling link between neurons and muscles in the fruit fly is essential for keeping the insect's nervous system stable.

1 Sep 2005

Study provides first steps toward individualized treatment of serious injuries

A multi-institutional research collaborative has begun to decipher the complex interplay of genes that underlies the body's response to major injuries.

1 Sep 2005

New knowledge into the molecular mechanisms involved in tumor growth

Scientists at the University of North Carolina at Chapel Hill have identified a molecular protein's critical role in cell division and growth.

26 Aug 2005

Discovery of signaling component that influences spread of breast cancer cells

Researchers at the Virginia Commonwealth University Massey Cancer Center have found a new signaling component that influences movement of human breast cancer cells toward epidermal growth factor.

22 Aug 2005

A cell's energy level is critical to its survival

In an ongoing effort to fight disease by manipulating energy regulation of cells, a collaborative study led by Dartmouth Medical School (DMS) has demonstrated that cells lacking a tumor-suppressing kinase called LKB1 can still maintain healthy energy levels when they become stressed.

22 Aug 2005

Increasing sugar processing in the liver may lead to future treatments for diabetes, obesity

Researchers at the University of Minnesota have shown that increasing the concentration of a key regulator involved in glucose metabolism can improve the way the liver produces and disposes of the sugar glucose, the primary fuel of the body. Finding ways to increase that concentration could provide a treatment for diabetes and obesity.

22 Aug 2005

Biochemical switch that affects how neurons fire in a part of the brain associated with learning

Researchers at UT Southwestern Medical Center have identified a biochemical switch that affects how neurons fire in a part of the brain associated with learning, findings that may aid in understanding schizophrenia and Alzheimer's disease.

17 Aug 2005

Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

Researchers from the University of Pittsburgh report the first study to achieve success with gene therapy for the treatment of congenital muscular dystrophy (CMD) in mice, demonstrating that the formidable scientific challenges that have cast doubt on gene therapy ever being feasible for children with muscular dystrophy can be overcome.

15 Aug 2005

Calcium fights prostate cancer

Calcium, more familiar in its role as one of the building blocks of the body, is being enlisted as a tool in the fight against prostate cancer.

15 Aug 2005

Key step in the production of beta-amyloid

Researchers at UT Southwestern Medical Center have defined a key step in the production of beta-amyloid, a short protein that is thought to be responsible for the development of Alzheimer's disease. Understanding this step may aid in the discovery of drugs that could help block the disease from developing.

11 Aug 2005

Researchers find drug targets for treating metabolic syndrome

Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition.

11 Aug 2005

New study points to new treatments for some forms of Lou Gehrig's disease

A new study indicates that mutant Cu/Zn superoxide dismutase (SOD1) enzymes that are associated with an inherited form of Lou Gehrig's disease cause the protein to become sticky in tissues. Partial unfolding of the mutant protein can expose hydrophobic residues that may promote abnormal interactions with other proteins or membranes in the cell.

11 Aug 2005

Researchers discover that tumors secrete fatty acids which inhibit the cytotoxic T lymphocytes' ability to kill tumor cells

Researchers have discovered that tumors release fatty acids that interfere with the cells that are trying to kill them. Consequently, strategies that reduce the amount of fatty acids surrounding the tumors may give a boost to anti-cancer therapeutics.

11 Aug 2005

Biochemists reveal the first structural details of microcompartments

UCLA biochemists reveal the first structural details of a family of mysterious objects called microcompartments that seem to be present in a variety of bacteria. The discovery was published Aug. 5 in the journal Science.

10 Aug 2005

New study aims to understand the intricate biochemistry governing gene regulation

In their efforts to understand the complex biology of life, scientists often seek to isolate individual elements of the puzzle for study, to break the problem down to a more manageable size. Single genes and molecules are closely analyzed to better understand their specific interactions with other single entities within larger systems.

4 Aug 2005

Primordial soup where life began on earth was hot and not cold

A new theory that explains why the language of our genes is more complex than it needs to be also suggests that the primordial soup where life began on earth was hot and not cold, as many scientists believe.

2 Aug 2005