Clinical Trial News and Research

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Pre-operative immunotherapy can elicit an immune response that shrinks oral cancers

A new clinical trial suggests that immunotherapy given before other treatments for oral cavity cancers can elicit an immune response that shrinks tumors, which could provide long-term benefit for patients.

27 Feb 2020

Renishaw completes main part of Phase 1-2 clinical trial along with Herantis Pharma for treatment of Parkinson’s disease

Global engineering technologies company, Renishaw, announces that its award-winning intraparenchymal drug delivery device, has played a critical role in a joint Phase 1-2 clinical study with Herantis Pharma plc, for the investigation of cerebral dopamine neurotrophic factor (CDNF)as a treatment for Parkinson's disease.

27 Feb 2020

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

APEIRON Biologics AG, a biotechnology company with an approved product on the market as well as a broad preclinical and clinical pipeline, today announced the launch of a Pilot investigator-initiated clinical trial with APN01, a recombinant human angiotensin-converting enzyme 2, to treat patients with severe coronavirus infection in the People's Republic of China.

26 Feb 2020

New multi-sensor tool quickly measures subtle changes in MS patients

Multiple sclerosis (MS) is a progressive, chronic disorder in which the body's immune system attacks the central nervous system, resulting in multiple adverse effects, from numbness, fatigue and impaired speech to loss of muscle control and vision.

26 Feb 2020

Coronavirus vaccine trials commence

The coronavirus disease (COVID-19) outbreak has swept the world, killing 2,770 people and infecting more than 81,000. Amid the health crisis, scientists from across the globe are racing to develop novel therapies and vaccines in the hope of stemming the spread of the deadly virus.

26 Feb 2020

First patient in U.S. treated for atrial fibrillation using new type of ablation technology

Cardiologists at The Ohio State University Wexner Medical Center are the first in the United States to test a new type of ablation technology for patients suffering from atrial fibrillation, a common type of irregular heartbeat.

26 Feb 2020

Biomarkers in blood samples can predict clinical response to immunotherapy in metastatic NSCLC

Non-small cell lung cancer patients with higher measures of tumor mutations that show up in a blood test generally have a better clinical response to PD-1-based immunotherapy treatments than patients with a lower measure of mutations.

26 Feb 2020

Renishaw Announces Completion of the Main Part of a Multi-Centre Clinical Trial Jointly Undertaken with Herantis Pharma plc for the Treatment of Parkinson’s Disease Patients

Renishaw, announces that its drug delivery device has played a critical role in the investigation CDNF as a treatment for Parkinson's disease.

From Renishaw plc - Additive Manufacturing for Healthcare Applications 26 Feb 2020

Ulcerative colitis and a missing microbe in the gut

Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from Stanford University School of Medicine have found in a new study that a missing microbe could be linked to this condition. The study was published today in the latest issue of the journal Cell Host & Microbe.

25 Feb 2020

Clinical trial to evaluate safety, efficacy of remdesivir in adults with COVID-19 begins

A randomized, controlled clinical trial to evaluate the safety and efficacy of the investigational antiviral remdesivir in hospitalized adults diagnosed with coronavirus disease 2019 (COVID-19) has begun at the University of Nebraska Medical Center in Omaha.

25 Feb 2020

Novartis and DNDi to partner on development of new oral treatment for visceral leishmaniasis

Novartis and the Drugs for Neglected Diseases initiative, a not-for-profit research and development organization, have signed a collaboration and license agreement to jointly develop LXE408, as a potential new oral treatment for visceral leishmaniasis, one of the world's leading parasitic killers.

25 Feb 2020

New wearable sensor could help remotely detect critical changes in heart failure patients

A new wearable sensor that works in conjunction with artificial intelligence technology could help doctors remotely detect critical changes in heart failure patients days before a health crisis occurs and could prevent hospitalization, according to a study led by University of Utah Health and VA Salt Lake City Health Care System scientists.

25 Feb 2020

Common challenges facing drug development and reimbursement for rare diseases

Approximately 90% of rare diseases still have no effective treatments, despite regulators implementing expedited approval pathways for these indications.

25 Feb 2020

Scientists developing a combined vaccine to fight most malignant brain tumor

Scientists are developing a combined vaccine to fight the most deadly form of brain cancer.

25 Feb 2020

The golden state’s mixed record on lung cancer

It was a bewildering moment for Zach Jump, the American Lung Association's national director of epidemiology and statistics.

25 Feb 2020

Immunotherapy drug combination effective for patients with fast-growing neuroendocrine tumors

Many patients with rare, fast-growing neuroendocrine tumors respond well to a common immunotherapy drug combination, according to the first peer-reviewed publication out of DART, short for Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors, a unique rare cancer clinical trial.

24 Feb 2020

Antifibrinolytic agent could be a treatment for bleeding stroke

A common medication that reduces bleeding could be a treatment for bleeding stroke, particularly if administered quickly, according to late breaking science presented today at the American Stroke Association's International Stroke Conference 2020.

23 Feb 2020

Researchers study why colon cancer is more lethal in pediatric and young adult patients

Colon cancer is more likely to be lethal in children and young adults than middle-aged adults. In a single-institution study, researchers at The University of Texas MD Anderson Cancer Center, Houston, Tex., found that differences in mortality rates persist regardless of whether pediatric, adolescent, and young adult patients (aged 24 and younger) were born with a predisposition for colon abnormalities or disease and for the first time conclude that young people are more likely to have metastases outside the colon, into the abdominal cavity, when they are diagnosed.

23 Feb 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

UCI neuro-oncologist uses comprehensive approach to battle brain cancer

When you're facing a cancer diagnosis with an average survival span of 12 to 18 months, every milestone is a victory.

23 Feb 2020

Clinical Trial News and Research

Pre-operative immunotherapy can elicit an immune response that shrinks oral cancers

Renishaw completes main part of Phase 1-2 clinical trial along with Herantis Pharma for treatment of Parkinson’s disease

APEIRON Biologics launches clinical trial of respiratory drug to treat coronavirus infection

New multi-sensor tool quickly measures subtle changes in MS patients

Coronavirus vaccine trials commence

First patient in U.S. treated for atrial fibrillation using new type of ablation technology

Biomarkers in blood samples can predict clinical response to immunotherapy in metastatic NSCLC

Renishaw Announces Completion of the Main Part of a Multi-Centre Clinical Trial Jointly Undertaken with Herantis Pharma plc for the Treatment of Parkinson’s Disease Patients

Ulcerative colitis and a missing microbe in the gut

Clinical trial to evaluate safety, efficacy of remdesivir in adults with COVID-19 begins

Novartis and DNDi to partner on development of new oral treatment for visceral leishmaniasis

New wearable sensor could help remotely detect critical changes in heart failure patients

Common challenges facing drug development and reimbursement for rare diseases

Scientists developing a combined vaccine to fight most malignant brain tumor

The golden state’s mixed record on lung cancer

Immunotherapy drug combination effective for patients with fast-growing neuroendocrine tumors

Antifibrinolytic agent could be a treatment for bleeding stroke

Researchers study why colon cancer is more lethal in pediatric and young adult patients

UCI makes tremendous strides in prevention, early detection and treatment of cancer

UCI neuro-oncologist uses comprehensive approach to battle brain cancer

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