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Imaging using fundus autofluorescence can facilitate the diagnosis and monitoring of rare eye diseases

Uveitis is a rare inflammatory eye disease. Posterior and panuveitis in particular are associated with a poor prognosis and a protracted course of the disease. Diagnosis and monitoring can be challenging for healthcare professionals.

25 Apr 2024

Machine learning system offers new hope for diagnosis of rare genetic disorders

Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient using artificial intelligence.

25 Apr 2024

National study links air pollution to increased risk of heart attacks in Poland

Subpopulations at heightened risk for ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) due to air pollution.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

Opportunities and limitations of using a large language model to respond to patient messages

A new study by investigators from Mass General Brigham demonstrates that large language models (LLMs), a type of generative AI, may help reduce physician workload and improve patient education when used to draft replies to patient messages.

24 Apr 2024

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

24 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

Prostaglandin E2: The culprit behind tumor immune evasion

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this exactly happens.

24 Apr 2024

Paclitaxel treatment found to directly promote HBV replication and transcription

Hepatitis B virus (HBV) reactivation is commonly observed in individuals with chronic HBV infection undergoing antineoplastic drug therapy.

24 Apr 2024

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Driven by the overuse of antimicrobials, pathogens are quickly building up resistances to once-successful treatments.

24 Apr 2024

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

24 Apr 2024

Advanced insulin pumps enhance blood sugar management in type 1 diabetes

Blood sugar levels improve when adults with type 1 diabetes use modern insulin pumps. These are the findings of a study conducted at the University of Gothenburg.

24 Apr 2024

Anesthetic midazolam boosts survival after cardiac arrest

If a patient is successfully resuscitated after a cardiac arrest and circulation resumes, they are not out of the woods yet.

24 Apr 2024

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

Study assesses global discrepancies in COVID-19 management guidelines across WHO member states, revealing that many national guidelines do not fully align with WHO recommendations, especially in lower-resource countries.

23 Apr 2024

FTC chief says tech advancements risk health care price fixing

New technologies are making it easier for companies to fix prices and discriminate against individual consumers, the Biden administration's top consumer watchdog said Tuesday.

23 Apr 2024

Genetic insights into type 2 diabetes risk in childhood cancer survivors

Survivors of childhood cancer are at increased risk for cardiovascular disease, for which a risk factor is their greater prevalence of type 2 diabetes, with a disproportionate impact on those of non-European heritage.

23 Apr 2024

Alarming rates of pediatric injuries from mechanical bull riding exposed

A new study conducted by researchers at Loma Linda University Children's Health has shed light on the alarming rates of pediatric injuries resulting from mechanical bull riding.

23 Apr 2024

Analysis finds significant variations in national COVID-19 treatment recommendations

National clinical guidelines for the treatment of COVID-19 vary significantly around the world, with under-resourced countries the most likely to diverge from gold standard (World Health Organization; WHO) treatment recommendations, finds a comparative analysis published in the open access journal BMJ Global Health.

23 Apr 2024

Researchers aim to use AI for early screening and prognosis of Dry Eye Disease

Dry Eye Disease (DED) is one of the more common eye diseases, affecting up to 30% of the world's population.

23 Apr 2024

Immune dysfunction mechanism discovered in stroke and heart attack patients

Every year, between 250,000 and 300,000 people in Germany suffer from a stroke or heart attack.

23 Apr 2024

Hospital News and Research

Imaging using fundus autofluorescence can facilitate the diagnosis and monitoring of rare eye diseases

Machine learning system offers new hope for diagnosis of rare genetic disorders

National study links air pollution to increased risk of heart attacks in Poland

New system personalizes chemotherapy doses for cancer patients

Opportunities and limitations of using a large language model to respond to patient messages

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

Prostaglandin E2: The culprit behind tumor immune evasion

Paclitaxel treatment found to directly promote HBV replication and transcription

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Advanced insulin pumps enhance blood sugar management in type 1 diabetes

Anesthetic midazolam boosts survival after cardiac arrest

Global study reveals mismatch in COVID-19 treatment guidelines with WHO standards

FTC chief says tech advancements risk health care price fixing

Genetic insights into type 2 diabetes risk in childhood cancer survivors

Alarming rates of pediatric injuries from mechanical bull riding exposed

Analysis finds significant variations in national COVID-19 treatment recommendations

Researchers aim to use AI for early screening and prognosis of Dry Eye Disease

Immune dysfunction mechanism discovered in stroke and heart attack patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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