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Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs - with the addition of an also already FDA-approved complement inhibitor - are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Study reveals how HIV squirms its way into the nucleus during cell invasion

Because viruses have to hijack someone else's cell to replicate, they've gotten very good at it - inventing all sorts of tricks.

25 Jan 2024

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

The drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duchenne muscular dystrophy (DMD).

25 Jan 2024

Lunaphore and Acd Revolutionize Spatial Biology Research With the Launch of the First Fully Automated, Same-Section, Hyperplex Multiomics Application

Bio-Techne Corporation (NASDAQ: TECH) today announced that its spatial biology brands, Lunaphore and Advanced Cell Diagnostics (ACD), will launch the first fully automated spatial multiomics workflow with same-section hyperplex detection of RNA and protein biomarkers.

From Bio-Techne 25 Jan 2024

Scientific review explores adzuki beans' efficacy in diabetes prevention and management

Adzuki bean (Vigna angularis) supplementation to prevent and manage type 2 diabetes (T2D).

25 Jan 2024

Study addresses knowledge gap of clinical features and outcomes of Black patients with melanoma

Researchers identified patient- and tumor-level melanoma features in black individuals.

25 Jan 2024

New insights into why immunotherapy works for some cancers, not others

A multi-institutional study co-authored by University of Texas at Arlington scientists uncovered a mechanism by which cancer cells prevent the immune system from activating and attacking the cancerous invaders.

24 Jan 2024

Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

Researchers analyzed the toxicity concerns and advancements in mRNA therapeutics, focusing on their cellular toxicity, reactogenicity, and distribution, and discussed the challenges and benefits of mRNA research.

24 Jan 2024

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine, researchers from the Perelman School of Medicine at the University of Pennsylvania reported today in Nature Medicine.

24 Jan 2024

New study reveals key tissues involved in HIV rebound after treatment

In findings that have implications for potential new HIV therapies, researchers from Texas Biomedical Research Institute (Texas Biomed) used genetic sequencing techniques on the nonhuman primate version of the virus to identify that lymph nodes in the abdomen are the leading source of rebound infection after the first week of stopping antiretroviral treatment.

24 Jan 2024

Retinal thinning linked to Parkinson's disease progression and cognitive decline

Study reveals that increased thinning of parafoveal ganglion cell-inner plexiform layer (pfGCIPL) and peripapillary retinal nerve fiber layer (pRNFL) correlates with Parkinson's disease progression and cognitive decline.

24 Jan 2024

Novel macrolide- DEL-1 axis helps in bone regeneration and new bone formation

Periodontitis is characterized by the loss of teeth resulting from inflammation of gums due to bacterial infections.

24 Jan 2024

Curcumin spray shows promise in fighting SARS-CoV-2 and flu viruses

A study in the Virology Journal reveals a curcumin-containing oro-nasal film spray with potential antiviral activity against SARS-CoV-2 and influenza viruses, boosting mucosal immunity without cytotoxic effects.

24 Jan 2024

Tulane scientists uncover key player in COVID's cell attachment

When SARS-CoV-2 enters the human body, the virus' spike protein binds to a cell, allowing the virus to infiltrate and begin replicating.

24 Jan 2024

Immune component of breast milk shapes the gut environment of infant mice

An immune component of breast milk known as the complement system shapes the gut environment of infant mice in ways that make them less susceptible to certain disease-causing bacteria, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

24 Jan 2024

Genomics meets retinal imaging: A powerful fusion can predict future health

The retina is said to provide a window into a person's systemic health. In a new study published January 24th in Science Translational Medicine, physician-researchers from Mass Eye and Ear, a member of Mass General Brigham, and the Broad Institute of MIT and Harvard combined retinal imaging, genetics and big data to estimate how likely a person is to develop eye and systemic diseases in the future.

24 Jan 2024