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Stanford researchers successfully defeat C. difficile bacteria

Stanford University School of Medicine scientists successfully defeated a dangerous intestinal pathogen, Clostridium difficile, with a drug targeting its toxins rather than its life.

24 Sep 2015

MIT researchers devise new system to genetically engineer viruses to combat harmful bacteria

In the hunt for new ways to kill harmful bacteria, scientists have turned to a natural predator: viruses that infect bacteria. By tweaking the genomes of these viruses, known as bacteriophages, researchers hope to customize them to target any type of pathogenic bacteria.

23 Sep 2015

Radboud university medical center reveals how BCG vaccine works against tuberculosis

Not only the acquired immune system but also the innate immune system has a memory. And the BCG vaccine against tuberculosis can stimulate this memory. After a BCG vaccination the innate immune system responds better to a wide range of other infections. Mihai Netea and colleagues from Radboud university medical center discovered and described how that works. They think that the old vaccine could be useful for specific target groups, such as the elderly.

23 Sep 2015

New gene mutation linked to fatal swelling in unborn and newborn babies

Scientists have discovered a new gene mutation that causes potentially fatal swelling in unborn and newborn babies. Identifying the gene is the first step toward a future diagnostic test and targeted treatment for this condition.

23 Sep 2015

Prashant Mahajan awarded $5.76 million grant to study how febrile infants can avoid invasive procedures

Prashant Mahajan, M.D., professor of Pediatrics and Emergency Medicine, chief of the Division of Emergency Medicine in the Department of Pediatrics at Wayne State University and Children's Hospital of Michigan, has been awarded a five-year, $5.76 million grant (1R01HD085233) by the Eunice Kennedy Shriver National Institute of Child Health & Human Development of the National Institutes of Health.

23 Sep 2015

AmpliPhi's novel bacteriophage therapy demonstrates comparable efficacy to vancomycin in S. aureus lung infection model

AmpliPhi Biosciences Corporation, a global leader in the development of bacteriophage-based antibacterial therapies to treat drug-resistant infections, today announced experimental results highlighting that its prototype bacteriophage cocktail demonstrated comparable efficacy to vancomycin in reduction of Staphylococcus aureus in a murine lung infection model.

22 Sep 2015

New study calls for new treatments for carbapenem-resistant Enterobacteriaceae infection

Researchers at The Medicines Company presented data from a multi-national cohort that demonstrates the mortality and morbidity, and poor outcomes, associated with current therapies in patients with infections due to carbapenem-resistant Enterobacteriaceae (CRE). The data from this analysis has guided the design of the company’s on-going clinical studies of its Phase 3 compound, CARBAVANCE® (meropenem/RPX7009) and was presented at the Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) and the International Congress of Chemotherapy and Infection (ICC) joint meeting in San Diego, CA.

22 Sep 2015

Combination of TXA709 and cefdinir demonstrates synergistic antibacterial activity against MRSA

TAXIS Pharmaceuticals, a drug-discovery company focused on developing a new class of antibiotic agents to treat life-threatening, multidrug-resistant bacterial infections, announced the presentation of results demonstrating the synergistic antibacterial activity of its lead clinical candidate, TXA709, when combined with cefdinir, a third-generation cephalosporin antibiotic.

19 Sep 2015

Public lecture discusses the future beyond antibiotics

Pioneering research into bacteriophage therapy as an alternative to antibiotics will be discussed at this year’s Frank May Prize Lecture on Monday 21 September from 5.30 – 6.30pm in the Frank and Katherine May Lecture Theatre, Henry Wellcome Building at the University of Leicester.

17 Sep 2015

Pioneering ultrasonic device can improve cleaning of medical instruments, reduce risk of infection

Researchers from the University of Southampton have demonstrated how a pioneering ultrasonic device can significantly improve the cleaning of medical instruments and reduce contamination and risk of infection.

16 Sep 2015

Study: Skin microbiome can influence outcomes of chancroid

For years, researchers have known that the human skin is home to a diverse community of microorganisms, collectively known as the skin microbiome. Now a new study has shown that individuals with a particular skin microbiome can effectively clear bacteria that cause chancroid, a sexually transmitted disease common in the developing world that has been linked to enhanced HIV transmission.

16 Sep 2015

UGA microbiology researchers identify potential mechanism for neurodegenerative diseases

Microbiology researchers at the University of Georgia studying a soil bacterium have identified a potential mechanism for neurodegenerative diseases.

15 Sep 2015

Tackling MRSA with bacteriophage

MRSA is bad news. If you've never heard of it, here's what you need to know: It's pronounced MER-suh, it's a nasty bacterial infection and it can cause serious disease and death.

15 Sep 2015

Three-drug strategy effective against drug-resistant staph infection, finds new research

Three antibiotics that, individually, are not effective against a drug-resistant staph infection can kill the deadly pathogen when combined as a trio, according to new research.

15 Sep 2015

Umeå University chemist explores ways to decrease bacterial colonization

Among the bacterial infections that are most difficult to treat, chronic infections associated with bacterial biofilms are one of the most hazardous. Bacterial biofilms are densely packed communities of microbial cells surrounded with secreted polymers. In her doctoral thesis, chemist Shoghik Hakbyan has studied ways to decrease the bacterial colonization at Umeå University in Sweden.

14 Sep 2015

Virginia Tech scientists discover new treatments to target antibiotic-resistant bacteria

Virginia Tech researchers have discovered a new group of antibiotics that may provide relief to some of the more than 2 million people in the United States affected by antibiotic resistance.

14 Sep 2015

New UCLA study finds novel approach that may help delay declines in health

Why do some people remain healthy into their 80s and beyond, while others age faster and suffer serious diseases decades earlier? New research led by UCLA life scientists may produce a new way to answer that question -- and an approach that could help delay declines in health.

14 Sep 2015

Research opens up potential new pathways to vaccine development against HA-MRSA

New research led by NYU Langone Medical Center has uncovered why a particular strain of Staphylococcus aureus -- known as HA-MRSA -- becomes more deadly than other variations. These new findings open up possible new pathways to vaccine development against this bacterium, which the Centers for Disease Control and Preventions says accounts for over 10,000 deaths annually, mostly among hospital patients.

10 Sep 2015

Antibiotic resistance awareness: an interview with Professor Colin Garner

The threat of antibiotic resistance is very real. It is estimated that 700,000 people die each from resistant infections. In Europe the figure is 25,000 deaths and a similar number in the USA.

7 Sep 2015

Researchers identify two enzymes from Legionella bacteria that are vital for protein chemistry

A research group at Umeå University in Sweden, together with researchers in Munich, have identified two enzymes from the pathogenic Legionella bacteria that are very useful in chemically modifying proteins to be used in medical drugs. The result of the study is presented in the chemical journal Angewandte Chemie International Edition.

7 Sep 2015

Bacterial News and Research

Stanford researchers successfully defeat C. difficile bacteria

MIT researchers devise new system to genetically engineer viruses to combat harmful bacteria

Radboud university medical center reveals how BCG vaccine works against tuberculosis

New gene mutation linked to fatal swelling in unborn and newborn babies

Prashant Mahajan awarded $5.76 million grant to study how febrile infants can avoid invasive procedures

AmpliPhi's novel bacteriophage therapy demonstrates comparable efficacy to vancomycin in S. aureus lung infection model

New study calls for new treatments for carbapenem-resistant Enterobacteriaceae infection

Combination of TXA709 and cefdinir demonstrates synergistic antibacterial activity against MRSA

Public lecture discusses the future beyond antibiotics

Pioneering ultrasonic device can improve cleaning of medical instruments, reduce risk of infection

Study: Skin microbiome can influence outcomes of chancroid

UGA microbiology researchers identify potential mechanism for neurodegenerative diseases

Tackling MRSA with bacteriophage

Three-drug strategy effective against drug-resistant staph infection, finds new research

Umeå University chemist explores ways to decrease bacterial colonization

Virginia Tech scientists discover new treatments to target antibiotic-resistant bacteria

New UCLA study finds novel approach that may help delay declines in health

Research opens up potential new pathways to vaccine development against HA-MRSA

Antibiotic resistance awareness: an interview with Professor Colin Garner

Researchers identify two enzymes from Legionella bacteria that are vital for protein chemistry

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