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Researchers generate a transcriptomic map of the COVID brain

COVID-19 is known to be associated with multiple changes in gene expression, but many of these are also seen in chronic brain conditions as well as in some abnormal mental conditions. A recent study published on the preprint server bioRxiv in October 2020 uncovers the molecular basis of this association.

26 Oct 2020

Transcriptomics identifies possible COVID-19 therapies

By using a diverse set of transcriptomic SARS-CoV-2 signatures, US researchers put to use their previously developed drug repositioning pipeline to pinpoint potential drug candidates for the treatment of coronavirus disease (COVID-19). The study is currently available on bioRxiv preprint server.

26 Oct 2020

Study suggests 5’UTR of SARS-CoV-2 might be of pangolin coronavirus origin

Findings from a new genomic sequencing study support the hypothesis that the pangolin was the intermediate host for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that enabled transmission of the virus to humans.

26 Oct 2020

Nasal spray formulation of ivermectin for COVID-19 shows promise in pigs

Researchers in Argentina have conducted a pre-clinical study demonstrating the safety and pharmacokinetic performance of a new nasal spray formulation designed to suppress the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent that causes coronavirus disease 2019 (COVID-19).

26 Oct 2020

Joint Pathology Center selects Huron Digital Pathology’s image search engine to unlock vast knowledge contained in world’s largest human tissue repository

Huron Digital Pathology announced today that the Joint Pathology Center (JPC), the premier pathology reference center for the United States federal government and part of the US Defense Health Agency, has selected Huron’s artificial intelligence-enabled LagottoTM image search engine to index and search JPC’s growing digital image archive.

From Huron Technologies 26 Oct 2020

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

A new study published on the preprint server bioRxiv* in October 2020 reports the discovery of important viral genomic features that are crucial to its replication in the human airway cells, and its enhancing mutations which increase the rate of replication and determine its target cells.

26 Oct 2020

Small molecules block SARS-CoV-2 spike-ACE2 attachment

The search includes immunological agents, enzyme inhibitors, and soluble competitive inhibitors. Now, a new study published on the preprint server bioRxiv in October 2020 provides preliminary evidence that small molecules can inhibit viral entry by inhibiting spike-ACE2 attachment.

26 Oct 2020

New inhibitor of SARS-CoV-2 RNA translation

As the search for effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibitors continues, a recent study by Yale University School of Medicine researchers published on the preprint server bioRxiv in October 2020 reports the inhibitory effect of the drug merofloxacin on frameshifting during SARS-CoV-2 replication.

26 Oct 2020

Graphene-enhanced PPE for COVID-19

To tackle this need, nanotechnology researchers from Italy have suggested using bidimensional graphene to improve existing PPE kits. Their research is published on the preprint server medRxiv.

25 Oct 2020

Neuropilin-1: A new route of SARS-CoV-2 entry

A new study published in the reputed journal Science in October 2020 reports the potential therapeutic value of the second type of host transmembrane receptor, called neuropilins, which attach to the spike protein of SARS-CoV-2 and may enhance its infectivity.

25 Oct 2020

Arguing to undo the ACA. Harming Medicare. Do they go hand in hand?

It's a tried-and-true campaign strategy. Candidates go on the attack, claiming their opponent will do harm to Medicare. After all, people 65 and older are good about making it to the polls on Election Day. These voters are also generally motivated to protect the federal health insurance program for seniors.

23 Oct 2020

New versatile method to isolate individual cells with unique profiles

Researchers at Rice University and Baylor College of Medicine have developed a new method to isolate specific cells, and in the process found a more robust fluorescent protein.

23 Oct 2020

Social connections with China or Italy increase compliance with mobility restrictions

Residents of U.S. counties with more social connections (measured as Facebook friends) to China or Italy - the first countries to report major COVID-19 outbreaks - were more likely to adhere to social distancing restrictions at the onset of the pandemic, according to a new study.

23 Oct 2020

Scientists devise new method to map HIV's sugary shield in unprecedented detail

Scientists from Scripps Research and Los Alamos National Laboratory have devised a method for mapping in unprecedented detail the thickets of slippery sugar molecules that help shield HIV from the immune system.

23 Oct 2020

Clinical trial launched to test existing drugs for treatment of a rare blood cancer

A clinical trial designed to test existing drugs in the treatment of a rare blood cancer has been launched at the Universities of Birmingham and Warwick.

23 Oct 2020

Researchers identify molecular processes in kidney cells that attract and feed COVID-19

Although the lungs are a common target for COVID-19's cytokine storm, so are the kidneys, making the 1 in 4 U.S. adults with diabetes resulting in diabetic kidney disease at increased risk for virus mortality.

23 Oct 2020

Study reveals new and essential details of how photoreceptors work

Moving around in the half-light is difficult but not impossible. To help us in this undertaking we have the rods, a type of light-sensitive cells (photoreceptors) present in the retina of vertebrates, capable of detecting very low lights which allow to move about even in poorly lit cellars or caves.

23 Oct 2020

Research News and Research

Researchers generate a transcriptomic map of the COVID brain

Transcriptomics identifies possible COVID-19 therapies

Study suggests 5’UTR of SARS-CoV-2 might be of pangolin coronavirus origin

Nasal spray formulation of ivermectin for COVID-19 shows promise in pigs

Joint Pathology Center selects Huron Digital Pathology’s image search engine to unlock vast knowledge contained in world’s largest human tissue repository

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

Small molecules block SARS-CoV-2 spike-ACE2 attachment

New inhibitor of SARS-CoV-2 RNA translation

Graphene-enhanced PPE for COVID-19

Neuropilin-1: A new route of SARS-CoV-2 entry

Arguing to undo the ACA. Harming Medicare. Do they go hand in hand?

New versatile method to isolate individual cells with unique profiles

Social connections with China or Italy increase compliance with mobility restrictions

Scientists devise new method to map HIV's sugary shield in unprecedented detail

Clinical trial launched to test existing drugs for treatment of a rare blood cancer

Researchers identify molecular processes in kidney cells that attract and feed COVID-19

Study reveals new and essential details of how photoreceptors work

Molecular processes in kidney cells may increase diabetics' vulnerability to COVID-19 infection

Bone density and frame size of women associated with habitual use in domestic labor tasks

Neutrophils have more functions in the body than previously thought

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