Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Multivitamin supplements can optimize body's metabolic performance

Eating well is a difficult task for most people given the frantic pace of everyday living. Convenient pre-packaged and fast foods, rich in calories and low in nutrients, offer an easy solution to those short on time, but neglect to provide daily essential nutrients. And the short-changing of necessary nutritional requirements for good health is furthered by routine stress itself.

22 Mar 2011

Daily dose of safflower oil can help reduce cardiovascular disease

A daily dose of safflower oil, a common cooking oil, for 16 weeks can improve such health measures as good cholesterol, blood sugar, insulin sensitivity and inflammation in obese postmenopausal women who have Type 2 diabetes, according to new research.

22 Mar 2011

Polypill may serve as viable option for developing countries to treat CVD risk prevention

For a patient at high risk of cardiovascular disease, keeping up with what pills to take at different times of the day can be tedious. Window sills lined with prescription bottles - a pill for cholesterol, another for blood pressure, and an aspirin to keep blood thin and flowing - the list can get quite long and, as a result, many people, especially the elderly, often forget doses or take the wrong pill at the wrong time.

22 Mar 2011

FDA accepts Arisaph's ARI-3037MO IND for phase I human clinical trial

Arisaph Pharmaceuticals, Inc., a privately held drug discovery biopharmaceutical company, today announced that the U.S. Food and Drug Administration has accepted the Company's recently submitted Investigational New Drug application to evaluate ARI-3037MO in a phase I human clinical trial in healthy volunteers.

22 Mar 2011

Physical ill-health reduces life expectancy of people with severe mental illness

Physical ill-health is rife among the severely mentally ill in Britain, according to new research published today by the University of East Anglia (UEA).

21 Mar 2011

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

A study published online in this week's Nature Genetics demonstrates that tiny Locked Nucleic Acid (LNA)-based compounds developed by Santaris Pharma A/S can inhibit entire disease-associated microRNA families. This provides a potential new approach for treating a variety of diseases including cancer, viral infections, cardiovascular and muscle diseases.

21 Mar 2011

Deaths from heart attacks drop precipitously in Norway, reports NTNU researcher

Life was hard in occupied Norway during WWII, but the occupation had one surprising result: deaths from heart attacks dropped precipitously, because Norwegians ate less fat, smoked less and were more physically active.

19 Mar 2011

Journal of Clinical Lipidology publishes LipoScience LDL particle study results against CVD

LipoScience, Inc., a highly innovative diagnostic company that is advancing patient care by developing high value proprietary blood tests using nuclear magnetic resonance technology, today announced publication of a clinical study in the Journal of Clinical Lipidology demonstrating that in many people, low density lipoprotein cholesterol is a less accurate predictor of cardiovascular disease events than LDL particle number.

19 Mar 2011

British pie, mash and gravy meals too salty: Heart health experts

A new study by Consensus Action on Salt and Health (CASH) in the UK that looked at 526 pie, mash and gravy meals and products, found some meals to be extremely high in salt. A chicken and mushroom pie with chips or mash, gravy and peas from pub chain Wetherspoons contained an alarming 7.5g of salt, well over the daily maximum recommendation of 6g a day. All the pie and mash pub meals looked at contained more than 3g, half the daily maximum, the report said. The survey, conducted by YouGov, found that the mashed potato and gravy could significantly increase the salt content of a meal. According to CASH, while good progress has been made by supermarkets in cutting salt levels in pies, there are still too many products containing unnecessary quantities of salt.

17 Mar 2011

Major breakthrough in thrombosis

Scientists from the University of Reading have announced a major breakthrough in understanding how to control blood clotting which could lead to the development of new treatments and save the lives of thousands of people each year.

17 Mar 2011

Montreal Heart Institute and Cerenis commence CER-001 Phase 2 study in acute coronary syndrome

The Montreal Heart Institute today announced the start of the Phase 2 CHI-SQUARE (Can HDL Infusions Significantly QUicken Atherosclerosis REgression?) study of CER-001 in patients with acute coronary syndrome (ACS), in collaboration with Cerenis Therapeutics, a biopharmaceutical company developing novel high-density lipoprotein (HDL) therapies to treat cardiovascular and metabolic diseases.

16 Mar 2011

Human growth, height, size: Reasons to be small

Almost everybody these days thinks that it is best to be tall, meaning much taller than the average traditional height of Asian populations, and even taller than the current average height of populations in high-income countries. It is also often believed – though people might be shy to admit this – that tall people are intrinsically superior to short people. The expressions 'look up to' and 'look down on' are significant.

15 Mar 2011

Type 2 diabetes drug less likely to cause weight gain, raise cholesterol levels

An inexpensive type 2 diabetes drug that has been around for more than 15 years works just as well and has fewer side effects than a half-dozen other, mostly newer and more expensive classes of medication used to control the chronic disease, new Johns Hopkins research suggests.

15 Mar 2011

Cerenis commences CER-001 Phase 2 CHI-SQUARE study in patients with ACS

Cerenis Therapeutics, a biopharmaceutical company developing novel high-density lipoprotein therapies to treat cardiovascular and metabolic diseases, today announced the start of the Phase 2 CHI-SQUARE study of CER-001 in patients with acute coronary syndrome.

15 Mar 2011

Bariatric surgery can lead to long-term weight loss, reduce cardiac risk factors in obese adults

Bariatric surgery can result in long-term weight loss and significant reductions in cardiac and other risk factors for some severely obese adults, according to a scientific statement from the American Heart Association.

15 Mar 2011

Study: Statin use may reduce risk of high-grade prostate cancer

Men who take a certain class of cholesterol-lowering medicine, otherwise known as statins, may be 60 percent less likely to be diagnosed with high-grade prostate cancer.

15 Mar 2011

Omthera commences dosing in pivotal Epanova Phase III EVOLVE trial in patients with very high triglycerides

Omthera Pharmaceuticals, Inc., a privately-held emerging specialty pharmaceuticals company, announced today that the first patient has been dosed in its pivotal Phase III EVOLVE (EpanoVa fOr Lowering Very high triglyceridEs) trial for Epanova™, the Company's lead compound for the treatment of patients with very high triglycerides. Epanova is an Omega-3 fatty acid containing a novel formulation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

14 Mar 2011

BioInvent commences BI-204 phase II study in patients with acute coronary syndrome

BioInvent International AB announces today the dosing of the first patient in the phase II study of the Company's antibody, BI-204. The product candidate is being developed for secondary prevention of cardiovascular events in patients with acute coronary syndrome.

14 Mar 2011

Nanotechnology might provide greater efficacy of medicines for brain disease

Technology has been developed within Top Institute Pharma that helps medicines be absorbed quicker into the blood and thus be more effective. Researcher Hans de Waard, who is associated with the University of Groningen, will obtain his doctorate on this subject on March 11. De Waard: "Many current medicines are not easily dissolved in the digestive tract, which means that they barely reach the bloodstream.

14 Mar 2011

U-M's CoreValve trial to offer less invasive approach for patients with aortic stenosis

The University of Michigan Cardiovascular Center, a leader in heart valve replacement, will participate in a national clinical trial to offer patients a less invasive approach to replacing diseased aortic valves.

14 Mar 2011

Cholesterol News and Research

Further Reading

Multivitamin supplements can optimize body's metabolic performance

Daily dose of safflower oil can help reduce cardiovascular disease

Polypill may serve as viable option for developing countries to treat CVD risk prevention

FDA accepts Arisaph's ARI-3037MO IND for phase I human clinical trial

Physical ill-health reduces life expectancy of people with severe mental illness

Tiny Locked Nucleic Acid-based compounds inhibit entire disease-associated microRNA families

Deaths from heart attacks drop precipitously in Norway, reports NTNU researcher

Journal of Clinical Lipidology publishes LipoScience LDL particle study results against CVD

British pie, mash and gravy meals too salty: Heart health experts

Major breakthrough in thrombosis

Montreal Heart Institute and Cerenis commence CER-001 Phase 2 study in acute coronary syndrome

Human growth, height, size: Reasons to be small

Type 2 diabetes drug less likely to cause weight gain, raise cholesterol levels

Cerenis commences CER-001 Phase 2 CHI-SQUARE study in patients with ACS

Bariatric surgery can lead to long-term weight loss, reduce cardiac risk factors in obese adults

Study: Statin use may reduce risk of high-grade prostate cancer

Omthera commences dosing in pivotal Epanova Phase III EVOLVE trial in patients with very high triglycerides

BioInvent commences BI-204 phase II study in patients with acute coronary syndrome

Nanotechnology might provide greater efficacy of medicines for brain disease

U-M's CoreValve trial to offer less invasive approach for patients with aortic stenosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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