Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Study deciphers how misfolded protein drives dopaminergic neuron loss in Parkinson's

A so-called pathological protein long associated with Parkinson's disease has been found in a new study to trigger cells to increase protein synthesis, an event that eventually kills the subset of brain cells that die off in this neurodegenerative condition.

20 Dec 2023

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Study reveals that cytoglobin (cygb2) plays a crucial role in regulating cilia motility and organ laterality during development, highlighting its importance in NO signaling and cilia function.

19 Dec 2023

Embryonic immune sensor could key to creating patient-derived blood stem cells

A microbial sensor that helps identify and fight bacterial infections also plays a key role in the development of blood stem cells, valuable new insight in the effort to create patient-derived blood stem cells that could eliminate the need for bone marrow transplants.

19 Dec 2023

Nutritional labels on menus lead to healthier choices, cutting calories by up to 25%

Study analyzes nine years of data from Taco Bell restaurants, showing that nutritional menu labeling led to a 22-25% reduction in calories-per-transaction, supporting the effectiveness of the United States Patient Protection and Affordable Care Act of 2010 in promoting healthier dietary choices.

19 Dec 2023

Autopsy study provides new insights into yellow fever's impact on the heart

To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo's Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury.

19 Dec 2023

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding author of a new study in Nature, Structural Analysis and Inhibition of Human LINE-1 ORF2 Protein Reveals Novel Adaptations and Functions.

19 Dec 2023

NEMO protein's crucial role in Parkinson's defense revealed

Researchers have identified a mechanism that promotes the breakdown of harmful protein deposits. If it malfunctions, it can lead to Parkinson’s disease.

19 Dec 2023

New vaccine could offer affordable hope for millions with high cholesterol

Nearly two in five U.S. adults have high cholesterol, according to the Centers for Disease Control and Prevention (CDC). Untreated, high cholesterol can lead to heart disease and stroke, which are two of the top causes of death in the U.S. Worldwide;, cardiovascular diseases claim nearly 18 million lives every year, according to the World Health Organization.

19 Dec 2023

Breakthrough in Parkinson's research: Scientists identify protein synthesis pathway as culprit

19 Dec 2023

Study reveals hidden inactive form of p38a protein

p38a protein, a key enzyme in the regulation of various cellular functions, plays a crucial role in some diseases, including cancer, chronic inflammation, and neurodegenerative conditions.

19 Dec 2023

Groundbreaking genome-editing technique holds promise for treating Charcot–Marie–Tooth disease

Scientific advances in the last century have changed our world significantly. For example, the world of genetics has opened doors to a myriad of possibilities: augmented human capabilities, cures for diseases, and even changes to the course of evolution.

19 Dec 2023

Scientists design non-hallucinogenic psychedelic treatments potentially accelerating research on mental health benefits

Researchers identified 5-hydroxytryptamine 2A (5-HT2A) receptor (5-HT2AR) signaling pathways associated with psychedelic potential.

19 Dec 2023

Bridging ideas to IND: Nona Biosciences' year of impact in biotechnology

Amidst a backdrop of industry-wide hurdles like inflation, talent scarcities, and stringent regulatory landscapes, Nona Biosciences is showing great promise as an emerging global leader in biotechnology.

From Nona BioSciences 19 Dec 2023

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Researchers investigated the anticancer effects of drugs targeting human tumor-associated macrophages (TAMs) in vivo. In humanized murine models, they tested the effectiveness of an antibody to human signal regulatory protein alpha (SIRPα) for cancer immunotherapy.

19 Dec 2023

Common heart medication causes false positives on Alzheimer's blood test

Researchers from the University of Gothenburg, in collaboration with colleagues from University of Glasgow, present data that the drug Entresto (sacubitril/valsartan) which is commonly used for the treatment of cardiac failure leads to a marked reduction in plasma Aβ ratio, a candidate blood test for Alzheimer's disease (AD).

18 Dec 2023

Protein News and Research

Further Reading

Study deciphers how misfolded protein drives dopaminergic neuron loss in Parkinson's

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Embryonic immune sensor could key to creating patient-derived blood stem cells

Nutritional labels on menus lead to healthier choices, cutting calories by up to 25%

Autopsy study provides new insights into yellow fever's impact on the heart

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

NEMO protein's crucial role in Parkinson's defense revealed

New vaccine could offer affordable hope for millions with high cholesterol

Breakthrough in Parkinson's research: Scientists identify protein synthesis pathway as culprit

Study reveals hidden inactive form of p38a protein

Groundbreaking genome-editing technique holds promise for treating Charcot–Marie–Tooth disease

Scientists design non-hallucinogenic psychedelic treatments potentially accelerating research on mental health benefits

Bridging ideas to IND: Nona Biosciences' year of impact in biotechnology

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Common heart medication causes false positives on Alzheimer's blood test

Cinnamon extract shows promise in reducing obesity by inhibiting fat cell growth and boosting fat breakdown

T-cells step up to offer protection against COVID-19 in B-cell deficient patients

New vaccine strategy targets SARS-CoV-2's stable S2 subunit, offering broad protection against evolving variants

“Forever chemicals” could contribute to cancer metastasis in living organisms

New technique reveals hidden communication network in tumors

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