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Study explores humoral and cellular immunity conferred by second and third COVID-19 BNT162b2 vaccination in elderly

Researchers recently assessed SARS-CoV-2-specific humoral and cellular immune responses induced by the second and third doses of the BNT162b2 COVID-19 messenger ribonucleic acid-based vaccine in the elderly.

17 Feb 2022

Study explores differential immune responses against SARS-CoV-2 in adults and children

A new study revealed that the immune responses against SARS-CoV-2 and the clinical course of COVID-19 differs between children and adults.

17 Feb 2022

Frequency and function of SARS-CoV-2-specific T cells in individuals with pulmonary PASC

Researchers examined patients with pulmonary PASC of SARS-CoV-2 to determine the frequency and function of SARS-CoV-2-specific T cells in their blood.

17 Feb 2022

Developing nanoplatforms for direct drug delivery to T cells

T cells, also known as lymphocytes, have important roles in various immune reactions. However, there are only a few reports on delivery systems into T cells. Realizing this, it is essential to work and actively contribute in controlling immune systems.

16 Feb 2022

The long-term consequences of SARS-CoV-2 infection in people with HIV

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from the United States (US) analyzed a cohort of patients with human immunodeficiency virus (HIV) (PWH) recovering from coronavirus disease 2019 (COVID-19) and characterized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immune responses in these patients.

15 Feb 2022

New COVID-19 test can determine if individuals have been vaccinated, infected, both, or neither

Researchers have created a new T cell assay that allows discrimination of COVID-19 infection and vaccination, as well as the order in which these occurred.

11 Feb 2022

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

The study highlights the significance of mix-and-match vaccine regimens to diversify the immune responses against highly mutated variants of SARS-CoV-2 such as Omicron.

10 Feb 2022

Induction and stability of vaccine-specific antibodies in multiple sclerosis patients on different disease-modifying therapies

Researchers have investigated the lack of response to treatment in certain multiple sclerosis patients.

9 Feb 2022

The B and T cell responses to SARS-CoV-2

Researchers assess the correlation between humoral and cell-mediated responses to SARS-CoV-2 in symptomatic and asymptomatic individuals.

8 Feb 2022

NIH grant renewal will enable Nebraska scientist to advance research on virtual immune system

The renewal of a National Institutes of Health grant will enable a University of Nebraska-Lincoln researcher to continue developing a tool that illuminates the complex, multi-scale interplay of the immune system's many components.

8 Feb 2022

Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage

Researchers demonstrated that an MVA vector expressing the SARS-CoV-2 spike protein was 100% effective in preventing neuroinvasion and brain damage by SARS-CoV-2 in transgenic mice.

8 Feb 2022

Novel fast-spreading HIV-1 variant found circulating in the Netherlands

Researchers identify 17 individuals who were infected with a highly virulent variant of HIV-1.

7 Feb 2022

Investigating the immunology of COVID-19 infected children

Researchers published a new study that focused on the key principles of developmental immunology associated with immunobiology and the clinical impacts of COVID-19 infections in children and adults.

7 Feb 2022

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

A new study analyzes neutralizing antibodies and T-cell responses targeting the SARS-CoV-2 D614G, as well as some variants of concern.

7 Feb 2022

Evaluating delayed vaccination schedules for protection against SARS-CoV-2

Researchers conducted an observational study to compare the humoral and cellular responses in health care workers who had received two doses of the Pfizer-BioNTech vaccine at standard (3 to 6 weeks) and delayed (8 to 16 week) intervals.

7 Feb 2022

Booster vaccines found to augment T-cell responses to SARS-CoV-2 Omicron

In a recent study published in the latest issue of the journal Cell, a team of researchers evaluated T-cell reactivity to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant's spike (S) and non-spike proteins.

6 Feb 2022

Researchers discover a new function of anti-HIV-1 antibodies

Teams at the Institut Pasteur, CNRS, Vaccine Research Institute (VRI) and Université de Paris have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures.

6 Feb 2022

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

In a new study, researchers explored the systemic immune responses during the acute and convalescent phases of SARS-CoV-2 in children and adults with the same disease severity.

3 Feb 2022

The ability of individuals to cross-recognize the Omicron spike protein following vaccination or prior infection

Scientists studied the ability of T cells to react with the Omicron spike.

2 Feb 2022

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

The authors highlight that they have created a quantitative framework that allows the dynamic mechanism of the immune response to SARS-CoV-2 to be properly investigated.

2 Feb 2022

CD4 News and Research

Study explores humoral and cellular immunity conferred by second and third COVID-19 BNT162b2 vaccination in elderly

Study explores differential immune responses against SARS-CoV-2 in adults and children

Frequency and function of SARS-CoV-2-specific T cells in individuals with pulmonary PASC

Developing nanoplatforms for direct drug delivery to T cells

The long-term consequences of SARS-CoV-2 infection in people with HIV

New COVID-19 test can determine if individuals have been vaccinated, infected, both, or neither

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

Induction and stability of vaccine-specific antibodies in multiple sclerosis patients on different disease-modifying therapies

The B and T cell responses to SARS-CoV-2

NIH grant renewal will enable Nebraska scientist to advance research on virtual immune system

Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage

Novel fast-spreading HIV-1 variant found circulating in the Netherlands

Investigating the immunology of COVID-19 infected children

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

Evaluating delayed vaccination schedules for protection against SARS-CoV-2

Booster vaccines found to augment T-cell responses to SARS-CoV-2 Omicron

Researchers discover a new function of anti-HIV-1 antibodies

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

The ability of individuals to cross-recognize the Omicron spike protein following vaccination or prior infection

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

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