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India to deploy homegrown tech against COVID-19

When India's 1.3 billion people come out of a 40-day lockdown on 3 May, imposed to contain the spread of COVID-19, they can hope that a battery of technologies that the government is readying to deploy against the contagious virus could offer them some protection.

28 Apr 2020

Rice University wins prestigious grant to develop new therapies for sickle cell disease

A Rice University lab has won a prestigious National Institutes of Health grant to pursue gene-editing research it hopes will lead to a cure for sickle cell disease (SCD).

25 Apr 2020

New brain cell models created to evaluate therapies for Sanfilippo C syndrome

The Sanfilippo syndrome type C is a severe neurodegenerative disease which appearws during the first years of life and for which there is no treatment yet.

24 Apr 2020

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

Using induced pluripotent stem cells produced from the skin of a patient with a rare, genetic form of insulin-dependent diabetes called Wolfram syndrome, researchers transformed the human stem cells into insulin-producing cells and used the gene-editing tool CRISPR-Cas9 to correct a genetic defect that had caused the syndrome.

22 Apr 2020

CRISPR helps identify new protein potentially involved in Alzheimer’s disease

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "molecular scissors" of CRISPR/Cas9 to search for new genes related to the neurodegenerative disease.

21 Apr 2020

Experts identify new protein that leads to Alzheimer’s disease

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease.

21 Apr 2020

Study clears potential barrier to controlling mosquito-borne diseases

New research from entomologists at UC Davis clears a potential obstacle to using CRISPR-Cas9 "gene drive" technology to control mosquito-borne diseases such as malaria, dengue fever, yellow fever and Zika.

17 Apr 2020

Novel FIMP protein may help orchestrate mammalian fertilization

Fertilization is a fundamental process in sexual reproduction when the combination of male and female gametes blends genetic material to create a new unique individual. Now, researchers from Japan have identified a new factor that may help orchestrate this vitally complex life event.

16 Apr 2020

Researchers decode how immune sensor plays role in defending cells against intruders

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders.

15 Apr 2020

CRISPR may help in kidney-transplants by detecting viruses

An exciting new study published in the journal Nature Biomedical Engineering in April 2020 reports excellent results with a new test for two common viruses that infect kidney transplant patients. The levels of these viruses shoot up during the acute phase of rejection.

13 Apr 2020

Scientists examine the molecular causes of rare hereditary disease

Scientists in EMBL Barcelona’s Ebisuya group, with collaborators from RIKEN, Kyoto University, and Meijo Hospital in Nagoya, Japan, have studied oscillating patterns of gene expression, coordinated across time and space within a tissue grown in vitro, to explore the molecular causes of a rare human hereditary disease known as spondylocostal dysostosis.

5 Apr 2020

New method to treat blindness using retinal cell production

Scientists in Sweden have innovated a method of treating blindness using embryonic stem cells to produce retinal cells.

30 Mar 2020

Researchers discover new way to refine production of retinal cells to treat blindness

Researchers at Karolinska Institutet and St Erik Eye Hospital in Sweden have discovered a way to refine the production of retinal cells from embryonic stem cells for treating blindness in the elderly.

30 Mar 2020

Finding new treatments for muscular dystrophy with CRISPR-Cas9

A new study out of Boston's Children's Hospital has used the gene-editing tool CRISPR-Cas9 to explore the fatal genetic condition called facioscapulohumeral dystrophy (FSHD, one of the family of muscular dystrophies), and to test out the potential utility of various genes involved in this disorder. The research is published in the journal Science Translational Medicine.

25 Mar 2020

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Adaptive immunity is a powerful defense mechanism in vertebrates. A finely tuned interplay of different cell types provides a pathogen-specific immune response to eliminate for example bacteria and viruses.

13 Mar 2020

Prize-winning research offers a promising approach to improve regenerative medicine

Joana Neves is the 2019 grand prize winner of the Sartorius & Science Prize for Regenerative Medicine & Cell Therapy, for work that offers a promising approach to improve the outcome of regenerative stem cell-based therapies aimed at delaying age-related degenerative diseases.

12 Mar 2020

Cas9 News and Research

India to deploy homegrown tech against COVID-19

Rice University wins prestigious grant to develop new therapies for sickle cell disease

New brain cell models created to evaluate therapies for Sanfilippo C syndrome

Study: Patients’ genetically edited stem cells successfully reversed diabetes in mice

CRISPR helps identify new protein potentially involved in Alzheimer’s disease

Experts identify new protein that leads to Alzheimer’s disease

Study clears potential barrier to controlling mosquito-borne diseases

Novel FIMP protein may help orchestrate mammalian fertilization

Researchers decode how immune sensor plays role in defending cells against intruders

CRISPR may help in kidney-transplants by detecting viruses

Scientists examine the molecular causes of rare hereditary disease

New method to treat blindness using retinal cell production

Researchers discover new way to refine production of retinal cells to treat blindness

Finding new treatments for muscular dystrophy with CRISPR-Cas9

Max Planck researchers identify mechanistic basis of antigen receptor gene assembly

Prize-winning research offers a promising approach to improve regenerative medicine

Researchers find way to inactivate cancer protein with the help of another protein

Study uncovers novel relationships between SLCs and cytotoxic drugs in human cells

New genetic tool developed to label specific genes in human organoids

Gene-editing is more error-prone than thought, new findings suggest

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