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African Bundibugyo ebolavirus vaccine candidate to be advanced to clinical trials

Leading African biopharmaceutical company Minapharm Group, headquartered in Egypt with subsidiaries in Berlin, will receive up to US$16.5 million from the Coalition for Epidemic Preparedness Innovations (CEPI) to advance the development of a Bundibugyo ebolavirus vaccine candidate, strengthening efforts to develop vaccines to combat the fastest-growing and second-largest Ebola outbreak on record affecting the Democratic Republic of the Congo (DRC).

28 Aug 2026

Compound PF-04457845 slows motor decline in ALS mouse models

Amyotrophic lateral sclerosis (ALS) is a severe neurological disease that destroys nerve cells responsible for muscle movement.

28 Aug 2026

Newly identified cells protect lung tumors from immune attacks

Researchers at Columbia University have discovered a new type of cell that protects lung cancers from attacks by the immune system.

27 Aug 2026

Review explores complex links between obesity and cardiovascular diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Obesity, given its strong association with cardiovascular diseases (CVDs), is a major global public health issue attracting increasing attention.

27 Aug 2026

$15 million trial aims to improve treatment decisions for older AML patients

A newly funded national clinical trial initiative will gather critical evidence to determine the best treatment strategies for older adults with acute myeloid leukemia (AML), an aggressive, fast-moving blood cancer that leaves a substantial proportion of older patients facing uncertainty about whether to proceed to stem cell transplantation or continue non-transplant therapy.

27 Aug 2026

Study reveals how SGLT2 inhibitors improve failing heart function

Researchers have discovered that SGLT2 inhibitors, a class of drugs originally developed to treat diabetes and now widely used for heart failure, work by activating a key enzyme that helps heart cells produce and use energy more efficiently.

27 Aug 2026

Unexpected discovery points to a possible route for childhood brain tumor treatments

When researchers at Lund University investigated how the molecule UM171 works, a molecule used to make blood stem cells multiply, they made an unexpected connection.

27 Aug 2026

Ketogenic diet excels at reversing prediabetes and fatty liver

There is no shortage of popular diets to try, and they can generally produce weight loss if followed to the letter. But are all diet plans created equal in terms of reducing the cardiometabolic risks that come with obesity, such as Type 2 diabetes and liver disease?

27 Aug 2026

CAR T-cell therapy successfully reverses severe rheumatoid arthritis

Immunotherapies such as CAR T-cell therapy are used primarily to treat cancer. In the future, these patient-specific therapies, manufactured from patients' own immune cells, could also help cure autoimmune diseases.

27 Aug 2026

Scalable stem cell method advances off-the-shelf CAR-T therapies

Researchers at the Center for Regenerative Medicine (CReM) at Boston Medical Center (BMC) and Boston University (BU) have developed a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells (iPSCs), overcoming a longstanding challenge in the development of stem cell-based immunotherapies.

27 Aug 2026

Ketogenic diet provides greatest health benefits for treating obesity

A diet that severely limits carbohydrates but is high in fat has the greatest health benefits for people with obesity compared to a Mediterranean diet or a low-fat diet, according to a clinical trial publishing August 27 in the Cell Press journal Cell Metabolism.

27 Aug 2026

Salk researchers isolate specific neurons controlling complex social behaviors

Our brains constantly integrate information about both our internal state and our surroundings to determine how we behave.

27 Aug 2026

Egg yolk peptides protect brain cells from oxidative stress

As the human lifespan increases, so too does the risk of developing neurological disorders such as Parkinson's disease, Alzheimer's disease, anxiety and depression.

27 Aug 2026

Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration

Brain diseases, including dementia, have long been studied using experimental animals such as mice.

27 Aug 2026

UMass Amherst researcher wins $2.5 million to expand nanoparticle cancer vaccine study

Having established the effectiveness of her nanoparticle drug-delivery system for cancer immunotherapy, University of Massachusetts Amherst researcher Prabhani Atukorale, has been awarded $2.5 million from the National Institutes of Health to broaden the scope of her vaccine research to include treating those with active cancer.

27 Aug 2026

Optimized EAP regimen delivers outstanding mobilization effects in multiple myeloma and lymphoma patients

This prospective, multicenter phase II study was conducted across 12 medical institutions in China and registered at ClinicalTrials.gov (NCT05536154).

27 Aug 2026

New mutant rat model replicates human chronic kidney disease

Chronic kidney disease (CKD) is a major health burden affecting approximately one in ten adults globally. Even with improved treatments, many patients continue to have worsening loss of kidney function, resulting in the need for dialysis or transplantation.

27 Aug 2026