Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

New treatment could be a better option for patients with colon cancer

Targeted radioembolization alongside chemotherapy improved progress-free survival for patients with colon cancer that had metastasized to the liver, according to a study published in the Journal of Clinical Oncology.

17 Dec 2021

Study may lead to a paradigm shift in the care for adults who relapse from large B-cell lymphoma

A study published this month in the New England Journal of Medicine (NEJM) may change the standard of care for adults who relapse from large B-cell lymphoma.

17 Dec 2021

A Day in the Life of A Clinical Geneticist

In this interview, we spoke to Dr. Julian Barwell, a clinical geneticist, about his day-to-day roles and responsibilities as well as his career highlights.

17 Dec 2021

New drug combination may prevent GvHD after stem cell transplantation for blood cancers

A drug combination can safely prevent transplanted stem cells, known as a graft, from attacking the recipient's body, allowing them to develop into healthy new blood and immune cells, a new study shows.

14 Dec 2021

Researchers uncover a key role for SIRT1 enzyme in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive type of leukemia. Despite advances in treatments, patients have an extremely poor prognosis, highlighting the need to explore the genetic components that lead to the formation of T-ALL, as well as the need to discover new targeted therapeutic approaches and treatment resistance.

14 Dec 2021

Study may offer insights into novel therapeutic strategies to treat COVID-19 related blood clots

Blood clots or thromboembolic complications in patients with COVID-19 are associated with increased levels of various proteins that cause blood to clot, compared with people with blood clots unrelated to COVID-19, according to a small study by Yale Cancer Center researchers.

14 Dec 2021

Lymphoma patients can benefit from early CAR T treatment, study shows

Chimeric antigen receptor T-cell therapy or CAR T is a breakthrough treatment for patients with certain types of blood cancers.

13 Dec 2021

COVID-19 vaccines offer protection for multiple myeloma patients, but lesser than other cancer survivors

For patients with the blood cancer multiple myeloma, vaccination against COVID-19 provides some protection against coronavirus infection but to a far lower degree than the general population of cancer survivors, a new study by Dana-Farber Cancer Institute investigators shows.

13 Dec 2021

Large study reveals increased rates of myeloma precursor condition in high-risk groups

The first results from the largest screening study yet conducted in the United States of individuals at above-average risk for the blood cancer multiple myeloma have revealed higher rates of a myeloma precursor condition in older adults who are Black or who have a close family member with a current or past blood cancer.

13 Dec 2021

$Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma$

Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma

The final results from a national phase 2 study including researchers from Yale Cancer Center show the drug tipifarnib increased survival rates for patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).

13 Dec 2021

Combination treatment can provide long remissions for young patients with chronic lymphocytic leukemia

Young patients with chronic lymphocytic leukemia (CLL) can enjoy long remissions on the drug ibrutinib, but must stay on it indefinitely to keep the cancer in remission.

13 Dec 2021

Study offers new hope for large B-cell lymphoma patients

Of the 18,000 people diagnosed with large B-cell lymphoma each year, only half will be successfully treated with chemotherapy. The 9,000 remaining patients typically have poor outcomes, with only 25% responding to additional, higher-intensity chemotherapy, followed by a stem cell transplant.

13 Dec 2021

Drug combination without chemotherapy can be effective in treating older patients with Ph+ ALL

The combination of dasatinib, blinatumomab, and prednisone can be effective in treating older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who are not good candidates for intensive chemotherapy treatment.

13 Dec 2021

Novel immunotherapy shows promise for children, young adults with recurrent AML

An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return.

12 Dec 2021

Statistical models predict outcomes for patients receiving non-intensive AML therapy

An international team has developed statistical models to predict the risk of early death in patients being treated with non-intensive therapies for acute myeloid leukemia (AML).

12 Dec 2021

Novel therapy found to be safe and well-tolerated in patients with bone marrow cancer

Mount Sinai physician-scientists have found that a novel therapy for the bone marrow cancer myelofibrosis is safe and well-tolerated and is associated with modest improvements in patients in a Phase 1b clinical trial.

12 Dec 2021

Clinical studies show enhanced responses for lymphoma patients treated with axi-cel CAR T cell therapy

Three clinical studies led by researchers at The University of Texas MD Anderson Cancer Center demonstrated enhanced responses for patients with high-risk lymphoma treated with axicabtagene ciloleucel (axi-cel) chimeric antigen receptor (CAR) T cell therapy.

12 Dec 2021

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Mount Sinai scientists have become the first to report a potentially serious side effect related to a new form of immunotherapy known as CAR-T cell therapy, which was recently approved for the treatment of multiple myeloma.

11 Dec 2021

Study analyzes the contribution of AI to cancer patient care and vaccine design

Artificial Intelligence/Machine Learning (AI/ML) is the development of computer systems that are able to perform tasks that would normally require human intelligence. AI/ML is used by people every day, for example, while using smart home devices or digital voice assistants.

8 Dec 2021

Octapharma USA announces FDA approval of cutaquig 16.5% for pediatric PI patients

Octapharma USA today announced the U.S. Food & Drug Administration has approved cutaquig [Immune globulin, Subcutaneous (Human)-hipp, 16.5% Solution] for the treatment of pediatric patients age 2 and older with primary humoral immunodeficiency (PI). The FDA previously approved cutaquig for adults with PI.

7 Dec 2021

Hematology News and Research

Further Reading

New treatment could be a better option for patients with colon cancer

Study may lead to a paradigm shift in the care for adults who relapse from large B-cell lymphoma

A Day in the Life of A Clinical Geneticist

New drug combination may prevent GvHD after stem cell transplantation for blood cancers

Researchers uncover a key role for SIRT1 enzyme in T-cell acute lymphoblastic leukemia

Study may offer insights into novel therapeutic strategies to treat COVID-19 related blood clots

Lymphoma patients can benefit from early CAR T treatment, study shows

COVID-19 vaccines offer protection for multiple myeloma patients, but lesser than other cancer survivors

Large study reveals increased rates of myeloma precursor condition in high-risk groups

Study finds new treatment option for patients with relapsed or refractory peripheral T-cell lymphoma

Combination treatment can provide long remissions for young patients with chronic lymphocytic leukemia

Study offers new hope for large B-cell lymphoma patients

Drug combination without chemotherapy can be effective in treating older patients with Ph+ ALL

Novel immunotherapy shows promise for children, young adults with recurrent AML

Statistical models predict outcomes for patients receiving non-intensive AML therapy

Novel therapy found to be safe and well-tolerated in patients with bone marrow cancer

Clinical studies show enhanced responses for lymphoma patients treated with axi-cel CAR T cell therapy

Potentially serious side effect reported after CAR-T cell therapy for multiple myeloma

Study analyzes the contribution of AI to cancer patient care and vaccine design

Octapharma USA announces FDA approval of cutaquig 16.5% for pediatric PI patients

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