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New study highlights role of TANs in regulating T cell responses in patients with early-stage lung cancer

The microenvironment of tumors is a mix of cell types, mostly comprised of inflammatory cells. White blood cells, recruited from the blood and bone marrow, represent a significant portion of these inflammatory cells and influence nearly all steps of tumor progression.

15 Jul 2016

Researchers demonstrate important functional role of lincRNA in immune system

A long non-coding RNA (lincRNA) - called lincRNA-EPS - responsible for regulating innate immunity has been identified by a team of scientists at the University of Massachusetts Medical School.

14 Jul 2016

Moderate caloric restriction in healthy non-obese individuals reduces chronic inflammation

Eating less may help us lead longer, healthier lives, according to the new results from a large, multicenter study, led by researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University.

14 Jul 2016

UNC professor identifies research priorities to address VTE in cancer patients

More than 20 percent of all blood clots in veins occur in cancer patients. These clots, also known as venous thromboembolism (VTE), pose serious threats for cancer patients.

14 Jul 2016

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

A drug combination designed to enhance the immune system's ability to zero in and attack cancer cells has shown a pronounced therapeutic effect against advanced and metastatic cancers in mice, according to a Mayo Clinic study, published in the July 12 edition of the online journal Oncotarget.

12 Jul 2016

Researchers develop new technique to help GPs better diagnose UTI in children

Urinary tract infections (UTI) in young children can lead to kidney damage, but are notoriously difficult to diagnose in primary care because symptoms can often be vague and unclear.

12 Jul 2016

Shire’s Xiidra receives FDA approval for treating dry eye disease in adult patients

Shire plc announces that the U.S. Food and Drug Administration has approved Xiidra (lifitegrast ophthalmic solution) 5%, a twice-daily eye drop solution indicated for the treatment of the signs and symptoms of dry eye disease in adult patients.

12 Jul 2016

Study identifies new blood markers to accurately diagnose Gulf War Illness

Based on a study of 85 Gulf War veterans, Veterans Affairs researchers in Minneapolis have developed a tentative panel of blood markers they say can verify a diagnosis of Gulf War Illness with 90 percent accuracy.

11 Jul 2016

Scientists reveal how common symptomless condition can develop into myeloma

Researchers from the University of Birmingham and hospitals across the West Midlands have revealed how a common symptomless condition can develop into the blood cancer myeloma.

11 Jul 2016

Scientists identify set of genes that could predict clinical outcomes in patients with FLT3-ITD AML

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore have identified a set of genes, including DNMT3A, that could potentially be used to predict clinical outcomes of patients who suffer from a type of Acute Myeloid Leukemia (AML) associated with an FLT3 internal tandem duplication (FLT3-ITD) mutation.

8 Jul 2016

Clinical trial to evaluate safety of palbociclib drug in African American women with breast cancer

The first clinical trial to test a newly approved breast cancer drug specifically in African American patients is now enrolling at Georgetown Lombardi Comprehensive Cancer Center and will begin soon at five other institutions in Washington, DC, Maryland, Alabama and New Jersey.

7 Jul 2016

Study demonstrates role of leukocyte activation receptor CD69 in development of psoriasis

Scientists at the Centro de Investigaciones Cardiovasculares Carlos III have defined the key role of an immune-system receptor in the development of psoriasis, suggesting that it could serve as a therapeutic target for the control of this disease.

5 Jul 2016

Key differences in immune response may explain young children’s proneness to infecion

Schools are commonly known as breeding grounds for viruses and bacteria, but this may not necessarily be linked to hygiene.

4 Jul 2016

Inhalable ibuprofen holds potential to treat cystic fibrosis

Ibuprofen: You can buy it at any drug store, and it will help with that stabbing headache or sprained ankle. One of the ways it does so is by reducing inflammation, and it is this property that may also help patients with cystic fibrosis.

4 Jul 2016

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

A novel anti-interleukin 1-alpha antibody has shown a significant impact on symptoms, and a high level of safety and tolerability in patients with advanced colorectal cancer, according to phase III data presented at the European Society for Medical Oncology's 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

4 Jul 2016

SLU researchers receive federal grant to study Zika virus

Saint Louis University vaccine researchers have received $1.3 million in federal funding to study Zika, as part of a multi-site study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

1 Jul 2016

Scientists discover new way to predict risk for delayed recovery in children with AML

The chemotherapy treatments necessary to treat Acute Myeloid Leukemia (AML) in children can be grueling on the body, and can cause health-related complications during therapy, as well as long down the road after remission.

1 Jul 2016

Researchers find main cause of necrotizing enterocolitis-related lung damage in preemies

Johns Hopkins researchers report they have figured out a root cause of the lung damage that occurs in up to 10 percent of premature infants who develop necrotizing enterocolitis, a disorder that damages and kills the lining of the intestine.

29 Jun 2016

Allergy-causing immune cells play life-saving role in deadly C. difficile infection

Researchers at the University of Virginia School of Medicine have identified immune cells vital for protecting us from potentially fatal C. difficile infection. Surprisingly, those cells are often vilified for their role in causing asthma and allergies. But when it comes to C. difficile, they could be the difference in life and death.

29 Jun 2016

Therapeutic stem cells exit bloodstream in different way than previously thought

Researchers at North Carolina State University have discovered that therapeutic stem cells exit the bloodstream in a different manner than was previously thought. This process, dubbed angiopellosis by the researchers, has implications for improving our understanding of not only intravenous stem cell therapies, but also metastatic cancers.

29 Jun 2016

Leukocyte News and Research

New study highlights role of TANs in regulating T cell responses in patients with early-stage lung cancer

Researchers demonstrate important functional role of lincRNA in immune system

Moderate caloric restriction in healthy non-obese individuals reduces chronic inflammation

UNC professor identifies research priorities to address VTE in cancer patients

Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice

Researchers develop new technique to help GPs better diagnose UTI in children

Shire’s Xiidra receives FDA approval for treating dry eye disease in adult patients

Study identifies new blood markers to accurately diagnose Gulf War Illness

Scientists reveal how common symptomless condition can develop into myeloma

Scientists identify set of genes that could predict clinical outcomes in patients with FLT3-ITD AML

Clinical trial to evaluate safety of palbociclib drug in African American women with breast cancer

Study demonstrates role of leukocyte activation receptor CD69 in development of psoriasis

Key differences in immune response may explain young children’s proneness to infecion

Inhalable ibuprofen holds potential to treat cystic fibrosis

Novel anti-interleukin 1-alpha antibody shows promise in treating advanced colorectal cancer patients

SLU researchers receive federal grant to study Zika virus

Scientists discover new way to predict risk for delayed recovery in children with AML

Researchers find main cause of necrotizing enterocolitis-related lung damage in preemies

Allergy-causing immune cells play life-saving role in deadly C. difficile infection

Therapeutic stem cells exit bloodstream in different way than previously thought

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