Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

In a new study, researchers performed an in vitro analysis to isolate ultralong bovine heavy chains that showed binding with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related coronaviruses (CoVs).

24 Oct 2022

Viral shedding rate declines rapidly during the first year among people with HSV-1 genital infections

People with a genital infection of the herpes simplex virus type 1 (HSV-1), which usually causes cold sores, frequently shed the virus in the first months after infection, raising the risk that they might spread the virus to sexual partners during this time.

24 Oct 2022

Longitudinal cohort study of primary healthcare workers reveals long-lasting SARS-CoV-2 humoral immunity in the absence of vaccination

Researchers performed a longitudinal cohort study to assess the levels of immunoglobulins M (IgM), G (IgG), and A (IgA) against the spike and nucleocapsid proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Oct 2022

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

In a new study, researchers introduced a compact rapid detection kit that tests for the monkeypox virus using a combination of RPA and CRISPR technology.

24 Oct 2022

Study explores the stability of monkeypox viral DNA in various body fluid samples

Researchers used laboratory diagnostic testing data of monkeypox cases and performed. They performed mathematical modeling to predict how long monkeypox viral deoxyribonucleic acid (DNA) remains detectable in different body fluid samples.

24 Oct 2022

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Researchers gathered empirical evidence that past pandemics due to infectious pathogens shaped the present-day susceptibility of humans to diseases, such as autoimmune diseases.

24 Oct 2022

Effectiveness of COVID-19 vaccines in preventing hospitalizations among immunocompromised adults

Researchers investigated the efficacy of monovalent mRNA COVID-19 vaccines in immunocompromised adults during the Omicron dominance period starting December 2021.

24 Oct 2022

COVID-19 vaccination during pregnancy protects infants from SARS-CoV-2 infection

In a recent study under review at the Nature Portfolio journal and currently posted to Research Square* preprint server, researchers evaluated the efficacy of maternal coronavirus disease 2019 (COVID-19) vaccination against infection of infants with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Oct 2022

A novel approach for viral genomic surveillance

In a recent study posted to the bioRxiv* preprint server, researchers in the United States explored a novel technique to improve representation in viral genomic surveillance.

24 Oct 2022

Antibody-mediated protection against symptomatic COVID achieved at low serum neutralizing titers

In a recent study posted to the medRxiv* preprint server, researchers in the United States assessed the efficiency of protection mediated by antibodies against symptomatic coronavirus disease 2019 (COVID-19) at low serum-neutralizing titers.

24 Oct 2022

Analyses of 11 commercially available PCR kits to detect monkeypox virus DNA

In a recent study posted to the medRxiv* server, researchers in Germany and Switzerland evaluated 11 commercial reverse transcription-polymerase chain reaction (RT-PCR) kits (A to L) for Monkeypox virus (MPXV) detection.

23 Oct 2022

FebriDX point-of-care immunoassay can rapidly determine if an infection is bacterial or viral

Researchers explore whether FebriDx could differentiate between bacteria- and virus-induced immune responses during acute respiratory infection.

23 Oct 2022

Antiseptic chewing gum reduces SARS-CoV-2 viral load in exhaled air

A recent study determined the effectiveness of antiviral chewing gum in reducing oral viral load in the exhaled air of COVID-19 patients.

23 Oct 2022

Fully vaccinated U.S. frontline workers may experience reduced severity, duration, and viral shedding during SARS-CoV-2

Researchers investigated the association between two or three doses of the messenger ribonucleic acid (mRNA) COVID-19 vaccine and viral loads and symptoms during infections with different SARS-CoV-2 variants.

23 Oct 2022

The public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2 in Denmark

Researchers conducted a nationwide study in Denmark to assess the public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2.

22 Oct 2022

Are pediatric COVID-19 samples less infectious?

Researchers determine whether children are less hospitable to SARS-CoV-2 and, as a result, pose a lower risk of a viral spread than adults.

20 Oct 2022

CDC advises on monkeypox sample collection protocols after U.S. exposure case

A new study described a case of occupational monkeypox exposure and commented. They commented on the CDC’s advisory on collecting swab samples for monkeypox testing.

20 Oct 2022

UK hospital study explores whether monkeypox can be transmitted through aerosolized droplets and fomites

Researchers conducted an observational study to determine environmental contamination with the monkeypox virus in the hospital isolation rooms of monkeypox patients to understand potential exposures to healthcare workers.

20 Oct 2022

Investigating increased healthcare usage after SARS-CoV-2 infection

In a new study, researchers evaluated the post-acute burden of healthcare use after SARS-CoV-2 infection in adults.

20 Oct 2022

Beckman Coulter Life Sciences presenting at ASHG

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, will have a full team of dedicated professionals and informative programming at the American Society of Human Genetics (ASHG) Annual Meeting October 25-29, 2022 in Los Angeles, California at the Los Angeles Convention Center.

From Beckman Coulter Life Sciences 20 Oct 2022

Polymerase Chain Reaction News and Research

Further Reading

Bovine ultralong complementarity-determining region H3 found to cross-react with sarbecoviruses

Viral shedding rate declines rapidly during the first year among people with HSV-1 genital infections

Longitudinal cohort study of primary healthcare workers reveals long-lasting SARS-CoV-2 humoral immunity in the absence of vaccination

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

Study explores the stability of monkeypox viral DNA in various body fluid samples

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Effectiveness of COVID-19 vaccines in preventing hospitalizations among immunocompromised adults

COVID-19 vaccination during pregnancy protects infants from SARS-CoV-2 infection

A novel approach for viral genomic surveillance

Antibody-mediated protection against symptomatic COVID achieved at low serum neutralizing titers

Analyses of 11 commercially available PCR kits to detect monkeypox virus DNA

FebriDX point-of-care immunoassay can rapidly determine if an infection is bacterial or viral

Antiseptic chewing gum reduces SARS-CoV-2 viral load in exhaled air

Fully vaccinated U.S. frontline workers may experience reduced severity, duration, and viral shedding during SARS-CoV-2

The public health impact of the SARS-CoV-2 Omicron subvariant BA.5 relative to BA.2 in Denmark

Are pediatric COVID-19 samples less infectious?

CDC advises on monkeypox sample collection protocols after U.S. exposure case

UK hospital study explores whether monkeypox can be transmitted through aerosolized droplets and fomites

Investigating increased healthcare usage after SARS-CoV-2 infection

Beckman Coulter Life Sciences presenting at ASHG

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