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Mayo Clinic Digital Pathology aims to revolutionize pathology and accelerate medical breakthroughs

Against the backdrop of the 43rd Annual J.P. Morgan Healthcare Conference, Mayo Clinic announced the formation of Mayo Clinic Digital Pathology, designed on a platform architecture to boldly unlock the power of its extensive archive of digital slides to revolutionize pathology and accelerate medical breakthroughs.

13 Jan 2025

Genetic discoveries drive new approaches to treating cerebral vascular malformations

Cerebral vascular malformations (CVMs), including cerebral arteriovenous malformations (AVMs) and cavernous malformations (CCMs), have long posed challenges due to their complex origins and severe clinical implications.

13 Jan 2025

Lung cancer deaths decrease globally but risk factors still persist

Even though lung and related cancer deaths decreased in the world's 10 most populous countries from 1990 to 2019, these positive statistics do not address trends in mortality linked to tobacco use, air pollution and asbestos exposure.

9 Jan 2025

Unraveling the molecular mechanisms of disease-causing mutations

Most mutations which cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a massive study of human protein variants published today in the journal Nature. Unstable proteins are more likely to misfold and degrade, causing them to stop working or accumulate in harmful amounts inside cells.

9 Jan 2025

New AI system aims to improve real-world application of clinical trial results

A new study led by Winship Cancer Institute of Emory University and Abramson Cancer Center of University of Pennsylvania researchers demonstrates that a first-of-its-kind platform using artificial intelligence (AI) could help clinicians and patients assess whether and how much an individual patient may benefit from a particular therapy being tested in a clinical trial.

8 Jan 2025

Myriad Genetics and MD Anderson partner to evaluate molecular residual disease assay

The University of Texas MD Anderson Cancer Center and Myriad Genetics, Inc. today announced a five-year strategic alliance to accelerate the clinical evaluation and development of Myriad's molecular residual disease (MRD) assay.

7 Jan 2025

Researchers uncover diverse asthma endotypes in youths using nasal transcriptomics

The study highlights T2-low and T17-high asthma endotypes in minoritized youths, offering insights for precision medicine and improved asthma management.

7 Jan 2025

ING5 regulates metabolic reprogramming in lung cancer cells

Lung cancer, notorious for its high mortality rates, is a leading cause of cancer-related deaths globally, with metastasis being the primary contributor to poor patient outcomes.

6 Jan 2025

Study identifies novel IgAN loci through pleiotropy

IgA nephropathy (IgAN) is a prevalent form of primary glomerulonephritis characterized by the deposition of IgA in the glomerular mesangium, leading to a spectrum of histopathological lesions and a variable clinical course that can progress to end-stage renal disease in a significant proportion of patients.

2 Jan 2025

Wearable heart sound devices transform cardiovascular disease monitoring

Cardiovascular diseases remain a global health crisis, spurring an urgent demand for innovative diagnostic tools that enable early detection and effective treatment.

24 Dec 2024

Breakthrough study unravels molecular subtypes of breast cancer

Breast cancer, with its myriad subtypes, has long eluded a uniform treatment strategy. The disease's molecular complexity has rendered traditional, blanket treatments insufficient, particularly for the aggressive triple-negative form.

18 Dec 2024

New molecular imaging agent can accurately identify crucial cancer biomarker

A new molecular imaging agent can accurately identify a crucial biomarker found among many different types of cancer.

18 Dec 2024

Huntsman Cancer Institute joins innovative clinical trials program for blood cancers

Huntsman Cancer Institute at the University of Utah (the U) has joined other institutions in an innovative clinical trials program designed to match patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) with a clinical trial specifically designed for the genetic signature of their disease.

17 Dec 2024

Blood count stability reveals new pathways to personalized care

Researchers reveal that complete blood count setpoints are stable, patient-specific biomarkers that persist for decades, offering new avenues for personalized medicine and precision diagnostics.

12 Dec 2024

Personalized blood test setpoints offer early disease detection

A complete blood count (CBC) screening is a routine exam requested by most physicians for healthy adults.

11 Dec 2024

High-dose chemotherapy followed by autologous stem cell transplant ineffective for patients with mantle cell lymphoma

Late-breaking research reveals there is no benefit from high-dose chemotherapy followed by autologous stem cell transplant (ASCT) for patients with mantle cell lymphoma (MCL) in remission following their initial treatment.

11 Dec 2024

New biomarker testing protocol could shorten antibiotic treatment for sepsis

A major UK patient trial of a new biomarker testing protocol for sepsis, led by University of Manchester researchers, has shown it is possible to safely stop antibiotic treatment earlier than current care.

10 Dec 2024

Two distinct types of fatty liver disease identified

Researchers at Karolinska Institutet and the University of Gothenburg have identified two types of metabolic-associated fatty liver disease - a liver-specific type and a systemic type that affects other organs and tissues.

10 Dec 2024

Two new subtypes of MASH revealed with different risks and outcomes

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as nonalcoholic fatty liver disease (NAFLD), impacts roughly 30% of the global adult population.

9 Dec 2024

Depression genes amplify women's heart disease risk

Study reveals a sex-specific link between genetic risks for psychiatric disorders and cardiovascular diseases (CVDs), with women showing a higher risk of atrial fibrillation, coronary artery disease, and heart failure linked to genetic predisposition to major depression. Menopause and modifiable factors like BMI and smoking amplify these risks.

8 Dec 2024