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Study provides insights into genetics underlying debilitating pediatric kidney disease

New research provides insights into the genetics underlying a debilitating kidney disease in children. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, could lead to new diagnostics and, ultimately, treatments.

14 Jun 2018

African-American men with prostate cancer show stronger response to hormone therapy

African-American men with advanced prostate cancer might be more responsive than white men to an anti-androgen drug and steroids, according to a study led by Duke Cancer Institute researchers.

4 Jun 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

Sex hormone levels linked to higher risk of heart disease in post-menopausal women

In post-menopausal women, having a higher blood level of a male hormone (testosterone) and a higher ratio of the male-type to-female type (estrogen) of hormones is associated with a higher risk of heart disease later in life, according to research published today in the Journal of the American College of Cardiology.

28 May 2018

New case report reveals negative clinical impact of using biotin supplement

A new case report in the Journal of the Endocrine Society documents how a patient's use of a common biotin supplement, also known as vitamin B7, caused her to have clinically misleading test results, which prompted numerous consultations and unnecessary radiographic and laboratory testing.

21 May 2018

Clinical study supports usual medical care plus chiropractic care for low back pain

U.S military personnel with low back pain who received usual medical care plus chiropractic care reported moderate improvement in their pain intensity and disability compared with patients who received usual medical care alone.

18 May 2018

Guideline revisions for knee osteoarthritis have 'subtle but significant' impact on clinical practice

Recent updates in evidence-based recommendations have led to changes in the use of steroid and hyaluronic acid injection for patients with osteoarthritis of the knee, reports a study in the May 16, 2018 issue of The Journal of Bone & Joint Surgery.

18 May 2018

International study finds viable treatment option for people with mild asthma

A large international study led by a Hamilton researcher has found a patient-centric treatment that works for people with mild asthma.

17 May 2018

FDA allows KU Medical Center to begin clinical trial of novel cellular therapy for HR/SR aGvHD

The University of Kansas Medical Center announced that the U.S. Food and Drug Administration has cleared it to begin a first-in-human clinical trial of MSCTC-0010 in patients with de novo high-risk acute or steroid-refractory acute graft-versus-host disease (HR/SR aGvHD).

16 May 2018

Doctors use new non-invasive approach to treat nasal obstruction

Researchers at The Ohio State University Wexner Medical Center are exploring how small changes in the nasal cavity impact airflow and quality of life.

14 May 2018

Phase 2 study of dexpramipexole in hypereosinophilic syndromes meets its co-primary endpoints

Knopp Biosciences LLC today announced the publication of a report in the journal Blood that a Phase 2 study of dexpramipexole in hypereosinophilic syndromes met its co-primary endpoints.

10 May 2018

Study finds neuroinflammation in spinal cord, nerve roots of patients with chronic sciatica

A study by Massachusetts General Hospital investigators has found, for the first time in humans, that patients with chronic sciatica - back pain that shoots down the leg - have evidence of inflammation in key areas of the nervous system.

10 May 2018

Placental hormone level rises during pregnancy and reaches peak as fetuses approach full term

Just as a runner steadily builds up endurance in order to peak at just the right time, the placenta carefully calibrates how much of the hormone allopregnanolone it produces during pregnancy.

7 May 2018

Medical marijuana use reduces pain and need for opioid painkillers, finds study

A questionnaire of older men and women suffering from chronic pain who were given medical marijuana found that the drug significantly reduced pain and their need for opioid painkillers, Northwell Health researchers report.

2 May 2018

New studies could offer novel treatments for vision and eye conditions

Three new studies demonstrate research findings that could offer novel treatments for vision and eye conditions.

30 Apr 2018

Surgeons identify rates of C. difficile infection in patients undergoing common colon operations

Clostridium difficile infection is the most common hospital-acquired infection and a significant cause of increased hospital stay and cost for patients and payors alike.

11 Apr 2018

Quintupling inhaled steroid doses may not benefit children with asthma

Children with mild to moderate asthma do not benefit from a common practice of increasing their inhaled steroids at the first signs of an asthma exacerbation, according to clinical trial results published in The New England Journal of Medicine.

20 Mar 2018

Genetic variant discovery could improve safety, effectiveness of drugs for asthma and COPD

Research from the University of Liverpool, published today in Lancet Respiratory Medicine, identifies a genetic variant that could improve the safety and effectiveness of corticosteroids, drugs that are used to treat a range of common and rare conditions including asthma, and chronic obstructive pulmonary disease (COPD).

16 Mar 2018

New study shows connection between coffee and cannabis

It's well known that a morning cup of joe jolts you awake. But scientists have discovered coffee affects your metabolism in dozens of other ways, including your metabolism of steroids and the neurotransmitters typically linked to cannabis, reports a new study from Northwestern Medicine.

15 Mar 2018

EPA ramps up efforts to create high-throughput endocrine disruptor assays

Exposure to endocrine-disrupting chemicals can cause health effects, such as reduced fertility and increased incidences of obesity and diabetes. Two decades ago, Congress directed the U.S. Environmental Protection Agency to screen substances for this activity.

14 Mar 2018