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Researchers show how investigational antiviral drug stops coronavirus

A team of academic and industry researchers is reporting new findings about how exactly an investigational antiviral drug stops coronaviruses.

28 Feb 2020

New approach to identify pathogenic genes in virus strains at a glance

When new viruses or bacteria spread to humans, it is essential to clarify their special characteristics as quickly as possible.

27 Feb 2020

Scientists reveal ability to reverse Huntington's disease-causing DNA repeat mutations in the lab

Neurodegenerative diseases, like Huntington's disease and myotonic dystrophy, are often referred to as DNA repeat diseases, named because of long repeated sequences in the DNA of patients. Increasing repeat expansion length in the affected tissues contribute to earlier age of disease onset and worsen the progression and severity of the disease over time.

27 Feb 2020

First human vaginal non-redundant gene catalog released

University of Maryland School of Medicine's Institute for Genome Sciences researchers have created the first catalog of genes that comprise the community of microbes, which inhabit the human vagina.

26 Feb 2020

Study reveals the effects of pre-surgical chemotherapy on breast cancer genome

Results from one of the first studies to determine the effects of pre-surgical, or neoadjuvant, chemotherapy on the breast cancer genome offer up two key insights.

26 Feb 2020

New method to deliver an immune system 'uncloaking' device directly to cancer cells

Scientists at Johns Hopkins report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals' immune systems.

26 Feb 2020

New form of gene editing slows ALS progression in mice

With a new CRISPR gene-editing methodology, scientists from the University of Illinois at Urbana-Champaign inactivated one of the genes responsible for an inherited form of amyotrophic lateral sclerosis - a debilitating and fatal neurological disease for which there is no cure.

26 Feb 2020

Study identifies novel anti-aging targets

A recent study published in Nature has reported two conserved epigenetic regulators as novel anti-aging targets.

26 Feb 2020

Biomarkers in blood samples can predict clinical response to immunotherapy in metastatic NSCLC

Non-small cell lung cancer patients with higher measures of tumor mutations that show up in a blood test generally have a better clinical response to PD-1-based immunotherapy treatments than patients with a lower measure of mutations.

26 Feb 2020

Promega's custom manufacturing capabilities support rapid development of Logix Smart COVID-19 Test

Promega Corporation is being recognized by Utah-based Co-Diagnostics, Inc.

From Promega Corporation 26 Feb 2020

Gene-editing is more error-prone than thought, new findings suggest

The standard gene-editing tool, CRISPR-Cas9, frequently produces a type of DNA mutation that ordinary genetic analysis misses, claims new research published in the journal Proceedings of the National Academy of Sciences.

26 Feb 2020

Large non-protein coding gene regulates process vital to placental implantation in early pregnancy

Abnormal formation and growth of the placenta is considered an underlying cause of various pregnancy complications such as miscarriages, preeclampsia and fetal growth restriction.

25 Feb 2020

Genome research collaboration in Finland welcomes Janssen and Maze Therapeutics

FinnGen, a large-scale academic - industry, genome research collaboration in Finland now includes eleven industry partners with the addition of the Janssen Pharmaceutical Companies of Johnson & Johnson and Maze Therapeutics.

25 Feb 2020

Cultural transition to agriculture linked with emergence of human-adapted pathogens

Using Salmonella enterica genomes recovered from human skeletons as old as 6,500 years, an international team of researchers illustrates the evolution of a human pathogen and provides the first ancient DNA evidence in support of the hypothesis that the cultural transition from foraging to farming facilitated the emergence of human-adapted pathogens that persist until today.

25 Feb 2020

Promega introduces Wizard HMW DNA Extraction Kit ahead of AGBT 2020

Promega, a global biotechnology manufacturer, today launched its new Wizard HMW DNA Extraction Kit for researchers working with large fragments of genomic DNA.

From Promega Corporation 25 Feb 2020

Ancient DNA analysis provides insight into genetic history of Sardinia

A new study of the genetic history of Sardinia, a Mediterranean island off the western coast of Italy, tells how genetic ancestry on the island was relatively stable through the end of the Bronze Age, even as mainland Europe saw new ancestries arrive.

24 Feb 2020

DNA topological problems may cause lymphoma, study shows

Researchers from the Spanish National Cancer Research Centre, Madrid, and the Andalusian Molecular Biology and Regenerative Medicine Centre, Seville, published today a paper in Nature Communications that shows that DNA topological problems may cause endogenous DNA breaks that have a causal relationship with cancer.

24 Feb 2020

New way to chart human genome with CRISPR/nanopore sequencing technique

In search of new ways to sequence human genomes and read critical alterations in DNA, researchers at Johns Hopkins Medicine say they have successfully used the gene cutting tool CRISPR to make cuts in DNA around lengthy tumor genes, which can be used to collect sequence information.

24 Feb 2020

IDT's new xGen Prism DNA Library Prep Kit launched

Integrated DNA Technologies, a leading comprehensive genomics solutions provider, has launched the xGen Prism DNA Library Prep Kit, designed to produce high-quality Next Generation Sequencing data from precious but challenging samples, assisting in the early detection of cancer mutations and other applications.

From Integrated DNA Technologies 24 Feb 2020

Coriell researchers find new genetic indicator of obesity risk

Obesity is among the most common complex diseases in the United States and has been a stubborn public health challenge for decades. Its causes are wide ranging, but genetic heritability is increasingly understood to be an influential factor in determining a person's risk for the disease.

23 Feb 2020