Biochemistry News and Research

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Researchers attempt to quantify processes underlying cell heterogeneity

Combining the latest methods in gene splicing and computer modeling, Rice University researchers are trying to develop a predictive framework for one of the most basic and complex biological phenomena — cellular heterogeneity, or the ability of genetic clones to act and behave differently when exposed to the same set of environmental stimuli.

8 Nov 2004

Prevalence of occult HBV in hemodialysis patients is 4 to 5 times higher than standard HBsAg testing would suggest

Some kidney dialysis patients contract hepatitis B virus (HBV) during the course of their treatment, possibly from other members of the dialysis population with occult HBV.

8 Nov 2004

Atomic switch capable of discriminating color in a bacterial membrane protein

Researchers using extremely high resolution imaging have found an atomic switch capable of discriminating color in a bacterial membrane protein.

5 Nov 2004

Trial of new type of drug that attacks amyloid

Neuroscientists at the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia will begin a clinical trial testing a new type of drug that attacks amyloid, the protein substance that accumulates in the brains of Alzheimer’s disease patients.

4 Nov 2004

Study results suggest that metronidazole and clindamycin differ in their effects on microbes in women with bacterial vaginosis

In the first study to directly compare the emergence of antibiotic resistance following topical treatment between two antibiotics routinely prescribed for a common vaginal infection, researchers from the Magee-Womens Research Institute have found antibiotic-resistant bacteria more likely to develop with the drug clindamycin than metronidazole.

1 Nov 2004

Patent issued for nanotechnology bone biomaterial

Competitive Technologies announced today that patent number 6,808,561 has been issued by the US Patent Office for Dr. Brian R. Genge's nanotechnology bone biomaterial developed at the University of South Carolina (USC).

1 Nov 2004

First home-testing device for phenylketonuria (PKU) patients

Home-testing kits have made it easier for diabetics and hypertension patients to track their conditions, but such self-monitoring hasn’t been possible for people with phenylketonuria (PKU).

1 Nov 2004

Grant to develop high speed DNA sequence reader

Sequencing of the human genome is one of the major scientific advances of our time. But with 3 billion base pairs, initial sequencing of the human genome took 11 years and cost $1 billion to complete in 2002. Today, it costs up to $50 million to sequence 3 billion base pairs.

1 Nov 2004

Researchers help define Apolipoprotein E's role in the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease

A research team led by University of South Florida neuroscientist Huntington Potter, PhD, CEO of the Johnnie B. Byrd Sr. Alzheimer's Center & Research Institute, for the first time has defined how the protein Apolipoprotein E (ApoE) contributes to both the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease.

1 Nov 2004

Scientists identify crucial elements necessary for repairing damaged DNA

A team of University of Sussex-led scientists has identified crucial elements necessary for repairing damaged DNA - the blueprint for all living cells.

25 Oct 2004

Newly discovered gene could be a significant contributor to diabetes in Americans

A gene involved in the action of insulin is associated with type 2 diabetes and the body’s response to insulin, report scientists at Wake Forest University Baptist Medical Center.

25 Oct 2004

Discovery of new protein involved in regulating the second most commonly mutated tumor suppressor in human tumors

Scientists in Tokyo have discovered a new protein, named PICT-1, that is involved in regulating PTEN, the second most commonly mutated tumor suppressor in human tumors.

22 Oct 2004

Key discovery toward understanding mechanism associated with uncontrollable muscular movements

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Lou Gehrig's and Huntington's exhibit loss of nerve function in different ways, from memory lapses to uncontrollable muscular movements, but it is now believed that these diseases share many common molecular mechanisms.

22 Oct 2004

Molecule that helps DNA replicate may make good target for cancer therapy

In order to divide, cells must first replicate their chromosomes. Cells use an array of proteins to accomplish the job, including a large enzyme complex that synthesizes new strands of DNA.

21 Oct 2004

Researchers are one step closer to understanding how high carbohydrate diets lead to obesity and diabetes

Researchers at UT Southwestern Medical Center at Dallas are one step closer to understanding how high carbohydrate diets lead to obesity and diabetes.

19 Oct 2004

Discovery might improve design, effectiveness of anti-cancer drugs

Working with an enzyme that degrades anti-cancer drugs in humans, University of North Carolina at Chapel Hill biochemists and colleagues have made a discovery that they believe eventually could help improve such drugs’ design and effectiveness.

18 Oct 2004

New research collaboration investigates disease in newborn and elderly

The University of Otago's Christchurch School of Medicine and Health Sciences' 30 year expertise in free radical research will be a vital component of a new collaborative Centre of Research Excellence (CoRE), recently backed by major Government funding.

13 Oct 2004

Bionanotechnology that combines the strengths of nanotechnology and biochemistry to generate a new type of bionanomaterial

A team of University of Florida researchers has created tiny hybrid particles that can speedily root out even one isolated E. coli bacterium lurking in ground beef or provide a crucial early warning alarm for bacteria used as agents of bioterrorism and for early disease diagnosis.

11 Oct 2004

Studies reveal complex molecular choreography with implications for human health and disease

As interactions of cellular proteins increasingly take center stage in basic biomedical research, studies are revealing a complex molecular choreography with implications for human health and disease.

10 Oct 2004

Best way to protect yourself from digestive cancers is by eating right, not taking a pill

“The bottom line is to forget the antioxidant supplement and eat lots of whole grains, fresh fruits and vegetables,” said William Hart, Ph.D., R.D., associate professor of nutrition and dietetics at Saint Louis University. “Limit meat, high fat milk products and all other sources of fat.”

8 Oct 2004

Biochemistry News and Research

Researchers attempt to quantify processes underlying cell heterogeneity

Prevalence of occult HBV in hemodialysis patients is 4 to 5 times higher than standard HBsAg testing would suggest

Atomic switch capable of discriminating color in a bacterial membrane protein

Trial of new type of drug that attacks amyloid

Study results suggest that metronidazole and clindamycin differ in their effects on microbes in women with bacterial vaginosis

Patent issued for nanotechnology bone biomaterial

First home-testing device for phenylketonuria (PKU) patients

Grant to develop high speed DNA sequence reader

Researchers help define Apolipoprotein E's role in the formation of amyloid brain lesions and the memory loss associated with Alzheimer's disease

Scientists identify crucial elements necessary for repairing damaged DNA

Newly discovered gene could be a significant contributor to diabetes in Americans

Discovery of new protein involved in regulating the second most commonly mutated tumor suppressor in human tumors

Key discovery toward understanding mechanism associated with uncontrollable muscular movements

Molecule that helps DNA replicate may make good target for cancer therapy

Researchers are one step closer to understanding how high carbohydrate diets lead to obesity and diabetes

Discovery might improve design, effectiveness of anti-cancer drugs

New research collaboration investigates disease in newborn and elderly

Bionanotechnology that combines the strengths of nanotechnology and biochemistry to generate a new type of bionanomaterial

Studies reveal complex molecular choreography with implications for human health and disease

Best way to protect yourself from digestive cancers is by eating right, not taking a pill

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