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Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020

Tulane establishes COVID-19 research program to develop a vaccine and test treatments

From working to develop one of the first nonhuman primate models for the 2019 novel coronavirus disease (COVID-19) to designing new therapeutic strategies and nanotechnology-based tests to rapidly diagnose infections, researchers at Tulane University are responding across disciplines to the emerging coronavirus epidemic.

21 Feb 2020

Scientists think they've found the earliest interbreeding event

A new study published in the journal Science Advances in February 2020 reports that it has found the earliest interbreeding event between different human populations ever, where the "super-archaics" of Eurasia interbred with another group known as the Neanderthal-Denisovan population long ago.

20 Feb 2020

New study uncovers human genes controlling HIV infection

Viruses are parasites. The only way they can grow is by hijacking their hosts. When they infect a human host, viruses use human proteins to multiply and modify the human cells to sustain the infection. At the same time, the human host activates defense mechanisms to fight the infection.

20 Feb 2020

New biomarkers for diagnosis and prognosis of lung cancer identified

Applying bioinformatics to resolve biological problems. This is the objective of the research group of the University of Malaga "BI4NEXT", which, in one of its latest studies, developed in the Supercomputing and Bioinnovation Center based on biobank samples, has identified new biomarkers for the diagnosis, prognosis and even treatment of lung cancer.

20 Feb 2020

New C. elegans model will accelerate study of a rare disease

The model will permit to accelerate and reduce the price of the research, which is studying the mechanisms and the possible pharmacological targets for the neuronal alterations of this disease.

20 Feb 2020

Marine herbivorous fish could be the new source of protein for humans

A secret to survival amid rising global temperatures could be dwelling in the tidepools of the U.S. West Coast.

19 Feb 2020

Supersensitive nanomaterials hold promise for DNA analysis and next-generation drugs

In 1900, German physician Paul Ehrlich came up with the notion of a "magic bullet." The basic idea is to inject a patient with smart particles capable of finding, recognizing, and treating a disease. Medicine has pursued the magic bullet ever since.

19 Feb 2020

Study identifies new CoV responsible for the Wuhan outbreak

The 2019 novel coronavirus causes fatal pneumonia that has claimed over 1300 lives, with more than 52000 confirmed cases of infection by February 13, 2020, all in the span of just over a month.

18 Feb 2020

IU researcher identifies new genomic regions that increase skin cancer risk

An Indiana University cancer researcher has identified eight new genomic regions that increase a person's risk for skin cancer.

18 Feb 2020

Increased risk of uterine cancer linked to 24 gene variants

The risk of uterine endometrial cancer is increased by 24 gene variants that code for different cellular processes such as cell growth and death, gene regulation, and estrogen metabolism, according to a comprehensive review published in the Journal of Medical Genetics.

17 Feb 2020

Researchers map key atomic structures in measles, mumps, flu and RSV

Northwestern University researchers have, for the first time, determined the 3D atomic structure of a key complex in paramyxoviruses, a family of viruses that includes measles, mumps, human parainfluenza and respiratory syncytial virus.

17 Feb 2020

UT Southwestern scientists discover potential vulnerabilities in new coronavirus

UT Southwestern Medical Center data scientists analyzing genetic sequences of the COVID-19 coronavirus have identified potential vulnerabilities that could help in vaccine development and further study of the infectious disease now spreading worldwide.

17 Feb 2020

Novel technique to study gene splicing reveals new insights into the process

Genes are like instructions, but with options for building more than one thing. Daniel Larson, senior investigator at the National Cancer Institute, studies this gene "splicing" process, which happens in normal cells and goes awry in blood cancers like leukemia.

16 Feb 2020

Dormancy emerges as a natural evolutionary response to over-predation, study finds

Why do predators sometimes lay dormant eggs -- eggs which are hardy, but take a long time to hatch, and are expensive to produce?

16 Feb 2020

Generating genomes and encoding new abilities into artificial DNA

A new study to be presented at the American Association for the Advancement of Science (AAAS) in February 2020 will report on the generation of the world’s first artificially created bacterial genome using a digital design algorithm along with the synthesis of DNA building blocks on a large scale. This genome takes form by chemical rather than template-based synthesis. The research is published in the journal Proceedings of the National Academy of Sciences.

16 Feb 2020

Research reveals new pathogenic mechanism for influenza NS1 protein

Influenza is a deadly virus, with about 290,000 to 650,000 deaths worldwide each year. When pandemics hit, the toll can soar: The Spanish flu of 1918 caused 40 million to 50 million deaths, the Asian flu of 1957 caused 2 million deaths, and the Hong Kong flu of 1968 caused 1 million deaths.

16 Feb 2020