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Data on Alexion Pharmaceuticals' Soliris to be presented at the ASH meeting

Alexion Pharmaceuticals, Inc. today announced that researchers are scheduled to present data relating to Soliris® (eculizumab) as a treatment for patients with paroxysmal nocturnal hemoglobinuria (PNH) during the 51st Annual Meeting of the American Society of Hematology (ASH), to be held December 5 – 8, 2009 at the Ernst N. Morial Convention Center in New Orleans.

11 Nov 2009

Levulan PDT may reduce the rate of recurrence of SCCs in solid organ transplant recipients: Study

The results of an independent investigator study just published in the online version of Dermatologic Surgery demonstrate that Levulan(®) Photodynamic Therapy (PDT) may reduce the rate of recurrence of squamous cell carcinomas (SCCs) in solid organ transplant recipients (SOTRs), a population with a high incidence of nonmelanoma skin cancer.

10 Nov 2009

Baxter International lauds new Medicare education benefit for chronic kidney disease patients

Baxter International Inc. commends the Centers for Medicare and Medicaid Services (CMS) on announcing implementation plans for a new Medicare benefit that will provide Stage 4 chronic kidney disease patients with coverage for up to six sessions explaining their treatment options, such as transplantation, home peritoneal dialysis (PD), home hemodialysis (HHD) or clinic-based hemodialysis (HD).

From Baxter International Inc. 10 Nov 2009

Lesser rates of kidney/pancreas transplants for African Americans: Is physician bias the reason?

Physician bias might be the reason why African Americans are not receiving kidney/pancreas transplants at the same rate as similar patients in other racial groups. Dr. Keith Melancon, director of kidney and pancreas transplantation at Georgetown University Hospital and associate professor of surgery at Georgetown University Medical Center, and colleagues explore this phenomenon in the November issue of the American Journal of Transplantation.

10 Nov 2009

Study suggests a new improved treatment option for children with Hurler's syndrome

Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme - preventing or reducing organ and central nervous system damage from the often-fatal genetic disorder Hurler's syndrome.

10 Nov 2009

Astellas receives exclusive rights to develop and commercialize linaclotide compound in Asia

Ironwood Pharmaceuticals, Inc. and Astellas Pharma Inc. today announced that they have entered into an agreement providing Astellas exclusive rights to develop and commercialize the investigational compound linaclotide in Japan, Indonesia, Korea, the Philippines, Taiwan, and Thailand.

10 Nov 2009

Beta-Pro helps meet growing demand for human pancreatic islets

Beta-Pro LLC, a biotechnology firm that provides diabetes researchers with custom cellular and consulting services, has entered a new phase of growth as it bridges the widening gap between an inconsistent, low quality supply of human pancreatic islets and skyrocketing demand.

10 Nov 2009

FDA approved stem cell therapy restores limb function in rats with neck spinal cord injuries

The first human embryonic stem cell treatment approved by the FDA for human testing has been shown to restore limb function in rats with neck spinal cord injuries - a finding that could expand the clinical trial to include people with cervical damage.

10 Nov 2009

New technique to identify patients more likely to survive advanced melanoma

Although the chances of surviving advanced melanoma aren't very good with current therapies, some patients can live for years with cancer that has spread beyond the skin to other organs. Now it may be possible to identify which patients are more likely to survive by analyzing the activity of hundreds of genes involved in the immune response and gene proliferation, according to researchers at NYU Langone Medical Center.

10 Nov 2009

Covidien contraindicates use of its Optimark gadoversetamide injection

Covidien, a leading global provider of healthcare products, today announced that it will voluntarily contraindicate the use of its Optimark™ gadoversetamide injection, a gadolinium-based contrast agent (GBCA), in magnetic resonance imaging (MRI) procedures involving patients with severe renal impairment.

9 Nov 2009

NewYork-Presbyterian Hospital celebrates 25th anniversary of pediatric heart transplantation

NewYork-Presbyterian Morgan Stanley Children's Hospital is celebrating the 25th anniversary of pediatric heart transplantation. In 1984, the Hospital's surgeons performed the world's first successful heart transplant, giving the gift of life to a 4-year-old boy.

7 Nov 2009

Genetix Pharmaceuticals develops a gene therapy product to treat ALD

Genetix Pharmaceuticals, a leader in gene therapy of somatic stem cells, announced today the company’s clinical program to treat Adrenoleukodystrophy (ALD). The company is developing a gene therapy product in collaboration with Professor Patrick Aubourg and Doctor Nathalie Cartier of the National Institute of Health and Medical Research (INSERM).

7 Nov 2009

Third-quarter 2009 financial results announced by Inhibitex

Inhibitex, Inc., today announced its financial results for the third quarter ended September 30, 2009. The Company held cash, cash equivalents and short-term investments of $21.1 million at September 30, 2009, as compared to $33.1 million at December 31, 2008.

6 Nov 2009

Gene therapy saves two children with adrenoleukodystrophy

The ELA association and Zinedine Zidane, its emblematic ambassador, are proud to announce a world premiere: the results regaring the gene therapy in adrenoleukodystrophy conducted in France have just been published in the prestigious journal Science. Two children have been treated and their diseases have been halted. The children are doing well, which is unexpected for a disease destroying the brain in a few months. This discovery opens up treatment perspectives for numerous widespread diseases.

6 Nov 2009

Successful leukemia treatment with a radiolabeled antibody followed by stem cell transplant

For the first time, researchers at Fred Hutchinson Cancer Research Center have reported the use of a radiolabeled antibody to deliver targeted doses of radiation, followed by a stem cell transplant, to successfully treat a group of leukemia and pre-leukemia patients for whom there previously had been no other curative treatment options.

6 Nov 2009

SynCardia Systems submits an IDE application for study of its Freedom discharge driver

On Nov. 5, SynCardia Systems, Inc., manufacturer of the SynCardia temporary CardioWest™ Total Artificial Heart, announced it has submitted an application to the FDA to conduct an Investigational Device Exemption (IDE) clinical study of the Freedom™ discharge driver, designed to power the Total Artificial Heart outside the hospital.

6 Nov 2009

Pfizer extends JAK3 research collaboration with Ligand Pharmaceuticals

Ligand Pharmaceuticals Incorporated announced today that its research collaboration with Pfizer for JAK3 has been extended by one year. The Research and License Agreement entered into in December 2006 with Wyeth provided for an initial three year research term. Under this extension, Ligand will receive $3.1 million in research payments to continue conducting drug discovery and lead candidate optimization.

6 Nov 2009

Study demonstrates potential of human Serum Amyloid P to block very aggressive fibrotic pathology

Promedior, Inc., a leader in the development of novel therapeutics for the treatment of fibrotic diseases and tissue remodeling, announced today the publication of results from preclinical studies demonstrating that human Serum Amyloid P (hSAP) potently inhibited fibrosis in two independent model systems of kidney fibrosis.

5 Nov 2009

Medivir presents OPERA-1 Phase IIa trial data at the AASLD meeting

Data were presented from the phase IIa trial (OPERA-1) for TMC435 at the ongoing 60th annual meeting of the American Association for the Study of Liver Diseases in Boston, USA.

4 Nov 2009

GI and hepatology societies take initiative to evaluate the current medical school curriculum

Due to the increasing complexities of treating digestive diseases, allowing gastroenterological (GI) trainee physicians the opportunity to develop enhanced abilities and experiences in specific disease areas or procedures will be a great benefit to patients, according to a "Report of the Multisociety Task Force on GI Training."

4 Nov 2009

Transplant News and Research

Data on Alexion Pharmaceuticals' Soliris to be presented at the ASH meeting

Levulan PDT may reduce the rate of recurrence of SCCs in solid organ transplant recipients: Study

Baxter International lauds new Medicare education benefit for chronic kidney disease patients

Lesser rates of kidney/pancreas transplants for African Americans: Is physician bias the reason?

Study suggests a new improved treatment option for children with Hurler's syndrome

Astellas receives exclusive rights to develop and commercialize linaclotide compound in Asia

Beta-Pro helps meet growing demand for human pancreatic islets

FDA approved stem cell therapy restores limb function in rats with neck spinal cord injuries

New technique to identify patients more likely to survive advanced melanoma

Covidien contraindicates use of its Optimark gadoversetamide injection

NewYork-Presbyterian Hospital celebrates 25th anniversary of pediatric heart transplantation

Genetix Pharmaceuticals develops a gene therapy product to treat ALD

Third-quarter 2009 financial results announced by Inhibitex

Gene therapy saves two children with adrenoleukodystrophy

Successful leukemia treatment with a radiolabeled antibody followed by stem cell transplant

SynCardia Systems submits an IDE application for study of its Freedom discharge driver

Pfizer extends JAK3 research collaboration with Ligand Pharmaceuticals

Study demonstrates potential of human Serum Amyloid P to block very aggressive fibrotic pathology

Medivir presents OPERA-1 Phase IIa trial data at the AASLD meeting

GI and hepatology societies take initiative to evaluate the current medical school curriculum

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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