Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Targeting VEGFA signaling in the epidermis can prevent psoriasis development

Psoriasis is a frequent skin inflammatory disorder affecting 3% of the population. Psoriasis is characterized by hyperproliferation and defect of epidermal differentiation, leading to the scaly appearance of the skin. The psoriasis skin also presents an increase in blood vessels, leading to the redness of the skin lesions and is associated with immune infiltration.

9 Jan 2020

Timing is key: preventing infant SHIV infection by PEP

Researchers tested methods to prevent development of SHIV, an infection similar to HIV, in infant macaque monkeys.

9 Jan 2020

Maternal microbiota is a source of newborn immunity, shows study

Mother's milk has been long touted for its salutary effects on the newborn and its ability to shield infants from certain infections.

9 Jan 2020

Researchers one step closer to developing vaccines that protect infants against infections

A new Penn Medicine study puts researchers within closer reach of vaccines that can protect infants against infections by overcoming a mother's antibodies, which are known to shut down immune defenses initiated by conventional vaccines.

9 Jan 2020

New test could help medics to quickly diagnose urinary tract infections

Biological Engineers at the University of Bath have developed a test that could help medics quickly diagnose urinary tract infections, using a normal smartphone camera.

8 Jan 2020

Pancreatic cancer cells release signal to suppress immune system's attack on tumors

A key immune signal has a previously unknown role in turning off the immune system's attack on pancreatic cancer cells, a new study finds.

8 Jan 2020

Single dose of antibody-based treatment can beat HIV in newborn babies

A single dose of an antibody-based treatment can prevent HIV transmission from mother to baby, new nonhuman primate research suggests for the first time. The findings are being published in the journal Nature Communications.

7 Jan 2020

New antibody-drug conjugate shows promising activity in salivary gland tumors

The antibody-drug conjugate ado-trastuzumab emtansine (T-DM1) has promising activity in HER2 amplified salivary gland tumors, according to data published in the Annals of Oncology.

7 Jan 2020

New sweat test could help detect a person’s marijuana-use

Forensic chemist Jan Halámek is proving that our own perspiration not only gives away how drunk we are – but if we are high, too.

6 Jan 2020

ART may not be completely effective in restoring immune protection, study suggests

A study led by researchers from SUNY Downstate Health Sciences University and Oregon Health & Science University, published in the Journal of Infectious Diseases, showed that, despite successful antiretroviral therapy, antigen specific memory to vaccinations that occurred before HIV infection did not recover, even after immune reconstitution.

6 Jan 2020

Researchers reveal how antibodies assemble to form a circle for defensive attack

Antibodies are key players in our immune system. These antibodies recognize antigens displayed on foreign cell membranes and thereby recruit attacking forces, called complements.

6 Jan 2020

Study shows the feasibility of using gene therapy to treat chronic traumatic encephalopathy

A new study shows the feasibility of using gene therapy to treat the progressive neurodegenerative disorder chronic traumatic encephalopathy.

3 Jan 2020

Measuring glycans in samples of antibodies

When Lorna De Leoz invited laboratories to participate in her glycomics study, she hoped for 20 responses. Instead, she was deluged by emails from around the world.

2 Jan 2020

Studying Alzheimer’s and Parkinson’s Disease using Pre-Formed Fibrils

Ariel Louwrier discusses the development of pre-formed tau and alpha-synuclein fibrils for research into Alzheimer's and Parkinson's disease.

From StressMarq Biosciences Inc. 2 Jan 2020

Common plasticizer leads to fertility problems in roundworms

A new study published 9th January in PLOS Genetics by Mónica Colaiácovo of Harvard Medical School and colleagues reports that the most commonly used plasticizer, diethylhexyl phthalate, leads to fertility problems by causing an excess number of breaks in the DNA during egg production, and then interfering with the repair systems that fixes the breaks.

2 Jan 2020

Bile acids help norovirus to infect cells of the small intestine

A new study led by researchers at Baylor College of Medicine and published in the Proceedings of the National Academy of Sciences reveals that human noroviruses, the leading viral cause of foodborne illness and acute diarrhea around the world, infect cells of the small intestine by piggybacking on a normal cellular process called endocytosis that cells use to acquire materials from their environment.

31 Dec 2019

New dementia vaccine may proceed to clinical trials after successful testing

A preventive treatment for dementia may proceed to clinical trials after successful animal testing.

31 Dec 2019

New combination of antibodies leads to more effective tumor destruction

The simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors.

30 Dec 2019

Study helps explain why previous attempts to develop a staph vaccine have failed

Staph bacteria, the leading cause of potentially dangerous skin infections, are most feared for the drug-resistant strains that have become a serious threat to public health.

26 Dec 2019

Sphingotec's new biomarker bio-ADM identifies ICU patients who need immediate organ support

Diagnostics company SphingoTec GmbH today announced a publication in Critical Care1 with data on 2,000 ICU patients demonstrating that sphingotec's proprietary biomarker bio-ADM (Bioactive Adrenomedullin) not only identifies high-risk patients for septic shock at admission but also identifies patients in the general ICU patient population who require immediate life-saving therapeutic intervention.

23 Dec 2019