Nerve News and Research

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BDNF molecule appears to play a direct role in regulation of blood pressure

Researchers at Oregon Health & Science University's School of Dentistry have made an important connection between a molecule critical to nerve cells and high blood pressure. Production of the molecule Brain-Derived Neurotrophic Factor (BDNF) appears to increase dramatically in blood pressure-sensing nerve cells during hypertension.

7 Dec 2012

Ketogenic diet and fasting can reduce seizures in children

Children with persistent and drug-resistant seizures treated with the high-fat, low-carbohydrate ketogenic diet may get an added therapeutic benefit from periodic fasting, according to a small Johns Hopkins Children's Center study.

7 Dec 2012

People with glaucoma show delayed eye movement reaction times

Rapid eye movements are significantly delayed in patients with glaucoma, even those in the early stages of the disease, research has found.

7 Dec 2012

Electrotherapy not effective pain treatment in the aftermath of pancreatic surgery

Osteopathy may help reduce chronic pain and stiffness after thoracic surgery. However, electrotherapy is not effective pain treatment in the aftermath of pancreatic surgery. These are the findings of a thesis from Sahlgrenska Academy, University of Gothenburg, Sweden, that studied complementary and alternative therapies.

6 Dec 2012

CINJ urologic oncology chief completes 1,000th robotic prostatectomy at RWJUH

Marking a major milestone in what has become a fast-growing standard of care in prostate cancer surgery, the chief of urologic oncology at The Cancer Institute of New Jersey has completed his 1,000th robotic prostatectomy at Robert Wood Johnson University Hospital (RWJUH), the Flagship Hospital of The Cancer Institute of New Jersey, which is a Center of Excellence of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School.

6 Dec 2012

Bisphenol A blocks calcium channels in cell membranes

Bisphenol A, a substance found in many synthetic products, is considered to be harmful, particularly, for fetuses and babies. Researchers from the University of Bonn have now shown in experiments on cells from human and mouse tissue that this environmental chemical blocks calcium channels in cell membranes. Similar effects are elicited by drugs used to treat high blood pressure and cardiac arrhythmia. The results are now presented in the journal "Molecular Pharmacology."

6 Dec 2012

No serious complications of regional nerve blocks in children

A review of more than 15,000 nerve block procedures performed in children at U.S. hospitals finds little or no risk of permanent complications or death, reports a study in the December issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

6 Dec 2012

Scientists develop MitoFish for in vivo studies of mitochondria transport in nerve cells

Scientists have demonstrated a new way to investigate mechanisms at work in Alzheimer's and other neurodegenerative diseases, which also could prove useful in the search for effective drugs. For new insights, they turned to the zebrafish, which is transparent in the early stages of its life. The researchers developed a transgenic variety, the "MitoFish," that enables them to see - within individual neurons of living animals - how brain diseases disturb the transport of mitochondria, the power plants of the cell.

6 Dec 2012

University of Florida initiates enrollment in SPI-1005 Phase II trial for sensorineural hearing loss

The University of Florida (UF) has started enrolling subjects in a new study testing the oral drug developed by Sound Pharmaceuticals, Inc. (SPI-1005) to prevent hearing loss caused by loud music. Loud music or noise can induce temporary and permanent auditory threshold shifts (TTS or PTS).

6 Dec 2012

Nerve stimulation improves hand use in spinal cord injury patients

A method combining transcranial magnetic stimulation with electrical stimulation of peripheral nerves in the wrist temporarily improves hand use in spinal cord injury patients, show research findings published in Current Biology.

5 Dec 2012

Selective targeting of neurotransmitters may allow for new medication therapies for GI conditions

Selective targeting of the neurotransmitter that differentially affects brain cells that control the two distinct functions of the pancreas may allow for new medication therapies for conditions like diabetes, dyspepsia and gastro-esophageal reflux, according to Penn State College of Medicine researchers.

5 Dec 2012

Parasympathetic dysfunction underpins Gulf War Syndrome

Gulf War veterans with self-reported symptoms of autonomic dysfunction have objective evidence of underlying damage to central and peripheral cholinergic function, a study shows.

4 Dec 2012

Kona Medical completes Series C financing

Kona Medical, Inc. today announced it has completed its Series C financing with the addition of $10 million in equity and debt, bringing total proceeds to $40 million.

4 Dec 2012

Researchers discover first-ever mouse model of diffuse idiopathic skeletal hyperostosis

Researchers at Western University have made a breakthrough that could lead to a better understanding of a common form of arthritis that, until now, has eluded scientists.

4 Dec 2012

Obstructive sleep apnea affects women more severely than men

Women suffering from sleep apnea have, on the whole, a higher degree of brain damage than men with the disorder, according to a first-of-its-kind study conducted by researchers at the UCLA School of Nursing.

3 Dec 2012

Diabetes tests: an interview with Dr. Danielle Stowasser

Diabetes is a serious condition that causes high levels of glucose (a type of sugar) in the blood. There are three main types of diabetes: type 1 and type 2 diabetes, which are lifelong conditions, and gestational diabetes, which only occurs in women during pregnancy.

3 Dec 2012

Pain can be treated by targeting immune and nerve cells outside brain or spinal cord

The treatment of inflammatory pain can be improved by endogenous opioid peptides acting directly in injured tissue. Scientists at the Charité - Universitätsmedizin Berlin and the Université Paris Descartes showed that pain can be successfully treated by targeting immune and nerve cells outside the brain or spinal cord.

3 Dec 2012

Childhood trauma can leave permanent epigenetic marks on DNA

Abused children are at high risk of anxiety and mood disorders, as traumatic experience induces lasting changes to their gene regulation. Scientists from the Max Planck Institute of Psychiatry in Munich have now documented for the first time that genetic variants of the FKBP5 gene can influence epigenetic alterations in this gene induced by early trauma.

3 Dec 2012

Children with changes in bully genes have poor survival

In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia (CHOP) found that patients with changes in two genes, ARID1A and ARID1B, survive only a quarter as long as patients without the changes. The discovery could eventually lead to early identification of patients with aggressive neuroblastomas who may need additional treatments.

3 Dec 2012

Low-level exposure to organophosphates affects neurological and cognitive function

Scientists have found that low-level exposure to organophosphates (OPs) produces lasting decrements in neurological and cognitive function. Memory and information processing speed are affected to a greater degree than other cognitive functions such as language.

2 Dec 2012

Nerve News and Research

BDNF molecule appears to play a direct role in regulation of blood pressure

Ketogenic diet and fasting can reduce seizures in children

People with glaucoma show delayed eye movement reaction times

Electrotherapy not effective pain treatment in the aftermath of pancreatic surgery

CINJ urologic oncology chief completes 1,000th robotic prostatectomy at RWJUH

Bisphenol A blocks calcium channels in cell membranes

No serious complications of regional nerve blocks in children

Scientists develop MitoFish for in vivo studies of mitochondria transport in nerve cells

University of Florida initiates enrollment in SPI-1005 Phase II trial for sensorineural hearing loss

Nerve stimulation improves hand use in spinal cord injury patients

Selective targeting of neurotransmitters may allow for new medication therapies for GI conditions

Parasympathetic dysfunction underpins Gulf War Syndrome

Kona Medical completes Series C financing

Researchers discover first-ever mouse model of diffuse idiopathic skeletal hyperostosis

Obstructive sleep apnea affects women more severely than men

Diabetes tests: an interview with Dr. Danielle Stowasser

Pain can be treated by targeting immune and nerve cells outside brain or spinal cord

Childhood trauma can leave permanent epigenetic marks on DNA

Children with changes in bully genes have poor survival

Low-level exposure to organophosphates affects neurological and cognitive function

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