Respiratory News and Research

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Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Researchers evaluated the synergistic activity of drugs acting against non-structural protein 1 of SARS-CoV-2 to decrease the viral infectivity.

2 Mar 2022

Study shows the viability of lung transplants in patients with COVID-19-associated ARDS

Patients with COVID-19-associated acute respiratory distress syndrome who received lung transplants had similar outcomes, compared to transplant patients without COVID-19, according to a Northwestern Medicine study published in JAMA.

2 Mar 2022

Dual therapeutic potential of zapnometinib against COVID-19

Researchers assessed the impact of the drug zapnometinib on human immune response against coronavirus disease 2019.

2 Mar 2022

Similarities between SARS-CoV-2 and human retroelements explored

A new study investigated the similarities between SARS-CoV-2 and human retroelements.

2 Mar 2022

Durability of immunity to SARS-CoV-2 reinfection among initially unvaccinated individuals with previous SARS-CoV-2 infection

An new study published presents evidence that a prior history of infection with SARS-CoV-2 provides immunity that prevents reinfection for at least a year.

2 Mar 2022

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.

2 Mar 2022

The prevalence of SARS-CoV-2 in environment and animal samples from the Huanan seafood market

A new study describes the surveillance of SARS-CoV-2 within the Huanan seafood market.

2 Mar 2022

Antigenic differences between Omicron BA.1 and BA.2 SARS-CoV-2 variants

A new study identifies the antigenic differences that exist between the Omicron BA.2 and BA.1 variants.

2 Mar 2022

Short-term change of depressive and anxiety symptoms in relation to COVID-19 vaccination

Researchers assess the short-term impacts of vaccination on the mental health of Swedish adults, with a primary focus on depression and anxiety.

2 Mar 2022

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

In a recent study an immunoPET technique that the authors were using to analyze SIV was adapted to evaluate the spatiotemporal dynamics of SARS-CoV-2 infection in a rhesus macaque model.

2 Mar 2022

Serological test to assess presence of immunoglobulin isotypes targeted against antigens routinely used in COVID-19 diagnosis

The current study discusses a reliable ELISA that can detect three isotypes of antibody against three SARS-CoV-2 antigens.

2 Mar 2022

Understanding the evolutionary mutational patterns of chronic SARS-CoV-2 infection

In a new study, researchers elucidated the factors driving adaptive evolution in chronic SARS-CoV-2 infections.

2 Mar 2022

Study reports substantial loss of protection one month after complete SARS-CoV-2 BNT162b2 immunization in children

A new study evaluated the efficacy of Pfizer’s BNT162b2 vaccine in children aged 17 years or younger after the emergence of the SARS-CoV-2 Omicron variant.

2 Mar 2022

Population-level health and economic impact of the Pfizer-BioNTech COVID-19 vaccine in first year of rollout in the US

A new study shows the impact of the vaccine program on the state of public health in the USA.

2 Mar 2022

More evidence points to the Wuhan Market as a source of the COVID-19 pandemic

Independent research groups have determined that SARS-CoV-2 was arguably initially present in the Huanan Seafood Wholesale Market – spilling over to people on two separate occasions.

2 Mar 2022

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has been shown to be a promising strategy for treating polymyositis.

2 Mar 2022

People in England limited contact with others even outside of lockdown periods, suggests study

Transmission of respiratory viruses depends partly on the rate of close social contacts in a population. A study publishing March 1st in PLOS Medicine by Amy Gimma at the London School of Hygiene and Tropical Medicine, United Kingdom, and colleagues suggests that during the most restrictive period of lockdown in the United Kingdom, the number of reported contacts decreased by 75% from pre-pandemic levels.

2 Mar 2022

A ubiquitous protein may be key to the survival of neurons most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

1 Mar 2022

Vapers, hookah smokers may expose the nose and sinuses to more emissions than cigarette smokers

People who smoke e-cigarette and hookah are more than twice as likely to exhale particles through their nose compared with people who smoke cigarettes, who favor exhaling the emissions from their mouth, a new study shows.

1 Mar 2022

Face masks can play a crucial role in reducing the spread of Covid infection

An international research team from universities including Chalmers University of Technology, Sweden, the University of Padua and the University of Udine in Italy, and the University of Vienna, Austria, has developed a new theoretical model to better assess the risks of spreading viruses such as Covid-19 - with and without a face mask.

1 Mar 2022

Respiratory News and Research

Triple drug regimen proven effective against non-structural protein-1 of SARS-CoV-2

Study shows the viability of lung transplants in patients with COVID-19-associated ARDS

Dual therapeutic potential of zapnometinib against COVID-19

Similarities between SARS-CoV-2 and human retroelements explored

Durability of immunity to SARS-CoV-2 reinfection among initially unvaccinated individuals with previous SARS-CoV-2 infection

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

The prevalence of SARS-CoV-2 in environment and animal samples from the Huanan seafood market

Antigenic differences between Omicron BA.1 and BA.2 SARS-CoV-2 variants

Short-term change of depressive and anxiety symptoms in relation to COVID-19 vaccination

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

Serological test to assess presence of immunoglobulin isotypes targeted against antigens routinely used in COVID-19 diagnosis

Understanding the evolutionary mutational patterns of chronic SARS-CoV-2 infection

Study reports substantial loss of protection one month after complete SARS-CoV-2 BNT162b2 immunization in children

Population-level health and economic impact of the Pfizer-BioNTech COVID-19 vaccine in first year of rollout in the US

More evidence points to the Wuhan Market as a source of the COVID-19 pandemic

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

People in England limited contact with others even outside of lockdown periods, suggests study

A ubiquitous protein may be key to the survival of neurons most impacted by glaucoma

Vapers, hookah smokers may expose the nose and sinuses to more emissions than cigarette smokers

Face masks can play a crucial role in reducing the spread of Covid infection

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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