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Phosphate linked to cause high blood pressure and heart disease

Researchers find link between phosphate rich foods and an enzyme linked to cardiovascular disease. The findings also link phosphates to renal disease.

6 May 2014

Characterization of Cajal-Retzius cells during development in mouse model of Alzheimer's disease

Cajal-Retzius cells are reelin-secreting neurons in the marginal zone of the neocortex and hippocampus.

6 May 2014

Study reveals how ovarian cancer metabolism changes between early, late stages

A Rice University-led analysis of the metabolic profiles of hundreds of ovarian tumors has revealed a new test to determine whether ovarian cancer cells have the potential to metastasize, or spread to other parts of the body. The study also suggests how ovarian cancer treatments can be tailored based on the metabolic profile of a particular tumor.

6 May 2014

FABP5 protein enhances cognitive function

Case Western Reserve researchers have discovered that a protein previously implicated in disease plays such a positive role in learning and memory that it may someday contribute to cures of cognitive impairments.

5 May 2014

New technique to examine how proteins interact at level of single HIV viral particle

An interdisciplinary team of scientists from KU Leuven in Belgium has developed a new technique to examine how proteins interact with each other at the level of a single HIV viral particle.

5 May 2014

Researchers identify novel proceed to treat brittle bone disease

Researchers at Baylor College of Medicine have identified a new approach to treating brittle bone disease, a congenital disorder that results in fragile bones that break easily.

5 May 2014

Puzzle in breast cancer solved

In a new study published in Cell Reports, scientists at the Fred Hutchinson Cancer Research Center demonstrate that mice lacking one copy of a gene called CTCF have abnormal DNA methylation and are markedly predisposed to cancer.

5 May 2014

Research: Novel therapeutic approach to overcome chemoresistance in ovarian cancer

Inhibiting enzymes that cause changes in gene expression could decrease chemotherapy resistance in ovarian cancer patients, researchers at Georgia State University and the University of Georgia say.

5 May 2014

Researchers discover potential genetic variant that may make brains more resilient against Alzheimer's

Autopsies have revealed that some individuals develop the cellular changes indicative of Alzheimer's disease without ever showing clinical symptoms in their lifetime.

5 May 2014

Pregnant women with obstructive sleep apnea more likely to die in hospital

Pregnant women with obstructive sleep apnea are more than five times as likely to die in the hospital than those without the sleep disorder, a comprehensive national study by the University of South Florida researchers found.

5 May 2014

Obese teens are likely to suffer nutritional deficiencies, says study

A new study exposes the risk of nutritional deficiencies in severely obese teens - both those who had weight loss surgery and those who did not.

5 May 2014

Women with elevated levels of liver enzyme prior to pregnancy twice as likely to develop gestational diabetes

Women with high levels of a common liver enzyme measured prior to pregnancy were twice as likely to subsequently develop gestational diabetes than those with the lowest levels, according to a Kaiser Permanente study published today in the journal Diabetes Care.

5 May 2014

UAMS receives $1.8M grant to lead new treatments for herpes viruses and cancers

A surprise discovery that could lead to new treatments for herpes viruses that infect more than 90 percent of the world's adult population has led to a $1.8 million grant to the University of Arkansas for Medical Sciences (UAMS) from the National Cancer Institute (NCI) at the National Institutes of Health (NIH).

5 May 2014

Johns Hopkins biochemists figure out HIV-fighting activity of enzyme

Johns Hopkins biochemists have figured out what is needed to activate and sustain the virus-fighting activity of an enzyme found in CD4+ T cells, the human immune cells infected by HIV. The discovery could launch a more effective strategy for preventing the spread of HIV in the body with drugs targeting this enzyme, they say.

2 May 2014

Isis Pharmaceuticals reports final data from ISIS-APOCIIIRx Phase 2 study in patients with FCS

Isis Pharmaceuticals, Inc. announced the final data from its Phase 2 study of ISIS-APOCIIIRx as a monotherapy in patients with familial chylomicronemia syndrome, or FCS.

2 May 2014

New research suggests that Kindlin-3 regulates 2 major hallmarks of breast cancer

A protein believed to be limited to the hematopoietic system, called Kindlin-3, has been identified as a major player in both the formation and spread of breast cancer to other organs.

2 May 2014

3 rules of thumb to reduce childhood obesity

Kristopher Kaliebe, MD, Clinical Assistant Professor of Psychiatry at the LSU Health Sciences Center New Orleans School of Medicine, offers parents and caregivers three simple family-oriented goals to overcome the complex problem of childhood obesity and related mental disorders.

2 May 2014

Virginia researchers develop new combination therapy that could potentially treat multiple myeloma

Each year, more than 25,000 Americans are diagnosed with multiple myeloma, a form of blood cancer that often develops resistance to therapies.

2 May 2014

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Northwestern Medicine- scientists have newly identified a protein's key role in cell and physiological aging and have developed - in collaboration with Tohoku University in Japan -- an experimental drug that inhibits the protein's effect and prolonged the lifespan in a mouse model of accelerated aging.

2 May 2014

Scientists receive $2.3M grant to develop new technology to diagnose cancer, rheumatoid arthritis and colitis

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded a $2.3 million grant from the National Institute of General Medical Sciences of the National Institutes of Health to develop new technology to diagnose cancer, rheumatoid arthritis and colitis.

2 May 2014

G Protein News and Research

Phosphate linked to cause high blood pressure and heart disease

Characterization of Cajal-Retzius cells during development in mouse model of Alzheimer's disease

Study reveals how ovarian cancer metabolism changes between early, late stages

FABP5 protein enhances cognitive function

New technique to examine how proteins interact at level of single HIV viral particle

Researchers identify novel proceed to treat brittle bone disease

Puzzle in breast cancer solved

Research: Novel therapeutic approach to overcome chemoresistance in ovarian cancer

Researchers discover potential genetic variant that may make brains more resilient against Alzheimer's

Pregnant women with obstructive sleep apnea more likely to die in hospital

Obese teens are likely to suffer nutritional deficiencies, says study

Women with elevated levels of liver enzyme prior to pregnancy twice as likely to develop gestational diabetes

UAMS receives $1.8M grant to lead new treatments for herpes viruses and cancers

Johns Hopkins biochemists figure out HIV-fighting activity of enzyme

Isis Pharmaceuticals reports final data from ISIS-APOCIIIRx Phase 2 study in patients with FCS

New research suggests that Kindlin-3 regulates 2 major hallmarks of breast cancer

3 rules of thumb to reduce childhood obesity

Virginia researchers develop new combination therapy that could potentially treat multiple myeloma

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Scientists receive $2.3M grant to develop new technology to diagnose cancer, rheumatoid arthritis and colitis

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The role of UV-Vis in biopharma QC

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