Immune System News and Research

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Multi-institution team receives prestigious award for breakthrough research on SARS-CoV-2

The Association for Computing Machinery (ACM) awarded its first ACM Gordon Bell Special Prize for High Performance Computing-Based COVID-19 Research to a multi-institution research team that included the U.S. Department of Energy's (DOE) Argonne National Laboratory.

20 Nov 2020

Scientists develop a new vaccine approach for HIV

Unlike so many other deadly viruses, HIV still lacks a vaccine. The virus--which continues to infect millions around the world--has proven especially tricky to prevent with conventional antibodies, in part because it evolves so rapidly in the body.

20 Nov 2020

Antibody combinations may be more effective at preventing, treating COVID-19

Pairs of antibodies may be more effective than single antibodies at preventing and treating COVID-19, according to a new study by researchers at the University of North Carolina at Chapel Hill and The Rockefeller University in New York.

19 Nov 2020

Texas Biomed awarded $1 million to evaluate MAb therapeutics for COVID-19

Texas Biomedical Research Institute in San Antonio, Texas, was awarded $1 million from the Bill & Melinda Gates Foundation to test the efficacy of human monoclonal antibodies (MAbs) for the treatment of SARS-CoV-2 infection.

19 Nov 2020

Study shows link between COPD and the gut microbiome

Research led by the Centenary Institute, the University of Technology Sydney and the University of Queensland has shown for the first time a link between chronic obstructive pulmonary disease (COPD), an often fatal lung condition, and the gut microbiome.

19 Nov 2020

UK’s COVID-19 vaccine shows similar safety and immunogenicity results in healthy older adults

The UK's vaccine against SARS-CoV-2 shows similar safety and immunogenicity results in healthy older adults (aged 56 years and over) to those seen in adults aged 18-55 years.

19 Nov 2020

Immune mechanism responsible for adverse inflammatory reactions after stem cell transplant identified

In the treatment of leukemia, stem cell transplantation subsequent to chemotherapy and radiation can often engender severe adverse inflammatory reactions - especially in the skin or in the gut, since these so-called barrier organs are more frequently affected.

19 Nov 2020

Triple RNA sequencing dissects gene expression of virus and fungi in infection processes

Organ and stem cell transplants are proven and frequently used methods in everyday modern clinical practice. However, even when performed regularly in specialized centers, some patients still experience a number of serious complications afterward.

19 Nov 2020

Brain protein plays a major role in the development and growth of pancreatic cancer

Researchers have discovered that a protein thought to only be involved in the development of neurons in the brain also plays a major role in the development and growth of pancreatic cancer.

18 Nov 2020

Immunotherapies effective against lung cancer, melanoma may also work against rare skin tumor

Cutaneous angiosarcoma is a rare, highly aggressive skin tumor found primarily on the scalps of older White people, but based on new research from the University of North Carolina School of Medicine and the Lineberger Comprehensive Cancer Center, immunotherapies effective against lung cancer and melanoma may also work against this cancer.

18 Nov 2020

Around 10 SARS-CoV-2 virions per cell in human body, study finds

A new study has found that there are about ten virus particles in each cell in the body. The research team from the Weizmann Institute of Science in Israel and the University of California in the USA estimate that each infected person carries around 109-1011 virions during peak infection.

18 Nov 2020

COVID-19 during pregnancy can cause placental inflammation and impaired immunity

A new study conducted by a team of researchers at Johns Hopkins University, USA, has observed how pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show stunted antiviral immune responses.

18 Nov 2020

Severe COVID-19 complications linked to gut barrier breakdown

A new study claims that severe COVID-19 is caused by a positive feedback loop triggered by systemic inflammation and mediated by abnormal gut permeability. This finding could potentially help open up new avenues of treatment.

18 Nov 2020

SARS-CoV-2 causes a unique cytokine storm, study finds

A new study published on the preprint server medRxiv* in November 2020 reports some of the unique elements of COVID-19-induced CRS and how understanding these distinctive characteristics of the disease could help in formulating specific interventions and therapies.

18 Nov 2020

COVID-19's harmful neurological effects are more common in patients with hypertension, diabetes

Some patients with COVID-19 are at higher risk of neurological complications like bleeding in the brain and stroke, according to a study being presented at the annual meeting of the Radiological Society of North America.

18 Nov 2020

Government-funded scientists laid the groundwork for billion-dollar vaccines

When he started researching a troublesome childhood infection nearly four decades ago, virologist Dr. Barney Graham, then at Vanderbilt University, had no inkling his federally funded work might be key to deliverance from a global pandemic.

18 Nov 2020

New study may shed light on the adaptive immune response to COVID-19

New research funded by the National Cancer Institute (NCI) aims to boost understanding of how the immune system responds to COVID-19, from the start of infection to recovery.

18 Nov 2020

Study reveals the metabolic signaling mechanisms that regulate function of eTreg cells

Effector regulatory T cells (eTreg cells) are a specialized subset of white blood cells that keep the immune system in check.

17 Nov 2020

UCLA researchers pinpoint how smoking causes more severe COVID-19 infection

UCLA researchers using a model of airway tissue created from human stem cells have pinpointed how smoking cigarettes causes more severe infection by SARS-CoV-2, the virus that causes COVID-19, in the airways of the lungs.

17 Nov 2020

SARS-CoV-2-specific IgM / IgG responses accurately predict COVID-19 outcome

Researchers from the Huazhong University of Science and Technology and Shanghai Jiao Tong University, China, recently built a proteome microarray with 20 out of the 28 predicted SARS-CoV-2 proteins to help understand IgM/IgG responses specific to SARS-CoV-2.

17 Nov 2020

Immune System News and Research

Multi-institution team receives prestigious award for breakthrough research on SARS-CoV-2

Scientists develop a new vaccine approach for HIV

Antibody combinations may be more effective at preventing, treating COVID-19

Texas Biomed awarded $1 million to evaluate MAb therapeutics for COVID-19

Study shows link between COPD and the gut microbiome

UK’s COVID-19 vaccine shows similar safety and immunogenicity results in healthy older adults

Immune mechanism responsible for adverse inflammatory reactions after stem cell transplant identified

Triple RNA sequencing dissects gene expression of virus and fungi in infection processes

Brain protein plays a major role in the development and growth of pancreatic cancer

Immunotherapies effective against lung cancer, melanoma may also work against rare skin tumor

Around 10 SARS-CoV-2 virions per cell in human body, study finds

COVID-19 during pregnancy can cause placental inflammation and impaired immunity

Severe COVID-19 complications linked to gut barrier breakdown

SARS-CoV-2 causes a unique cytokine storm, study finds

COVID-19's harmful neurological effects are more common in patients with hypertension, diabetes

Government-funded scientists laid the groundwork for billion-dollar vaccines

New study may shed light on the adaptive immune response to COVID-19

Study reveals the metabolic signaling mechanisms that regulate function of eTreg cells

UCLA researchers pinpoint how smoking causes more severe COVID-19 infection

SARS-CoV-2-specific IgM / IgG responses accurately predict COVID-19 outcome

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