Nerve News and Research

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Scientists uncover TDP-43 protein as possible target for treatment of ALS, FTD

Neuroscientists at Georgetown University Medical Center say they have new evidence that challenges scientific dogma involving two fatal neurodegenerative diseases - amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD) - and, in the process, have uncovered a possible therapeutic target as a novel strategy to treat both disorders.

20 Dec 2012

New therapeutic ultrasound approach could lead to an invisible knife for noninvasive surgery

A carbon-nanotube-coated lens that converts light to sound can focus high-pressure sound waves to finer points than ever before. The University of Michigan engineering researchers who developed the new therapeutic ultrasound approach say it could lead to an invisible knife for noninvasive surgery.

20 Dec 2012

Scientists map sensory nerves in mouse skin

Johns Hopkins scientists have created stunning images of the branching patterns of individual sensory nerve cells. Their report, published online in the journal eLife on Dec. 18, details the arrangement of these branches in skin from the backs of mice.

20 Dec 2012

Link made between muscular dystrophy and defective nerve wiring

Working with mice, Johns Hopkins scientists have discovered that a particular protein helps nerve cells extend themselves along the spinal cord during mammalian development. Their results shed light on the subset of muscular dystrophies that result from mutations in the gene that holds the code for the protein, called dystroglycan, and also show how the nerve and muscle failings of the degenerative diseases are related.

20 Dec 2012

AAV-based gene therapy cocktail may help extend lives of children with Canavan disease

Results of a clinical trial that began in 2001 show that a gene therapy cocktail conveyed into the brain by a molecular special delivery vehicle may help extend the lives of children with Canavan disease, a rare and fatal neurodegenerative disorder.

20 Dec 2012

Lou Gehrig's disease may be treatable using neural stem cells

Promising new research provides evidence that ALS, amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, may be treatable using neural stem cells.

20 Dec 2012

People with chronic shortness of breath may soon have new way to help alleviate their discomfort

People experiencing chronic shortness of breath may soon have a new way to help alleviate their discomfort, according to a Penn State College of Medicine pulmonology researcher.

20 Dec 2012

‘Sensory’ block promise for postop knee pain

Using adductor canal block rather than femoral nerve block for analgesia after knee surgery could minimize muscle weakness and risk for falls, a study in Anesthesiology suggests.

19 Dec 2012

Biologic changes after delivery may prevent development of chronic pain

Chronic pain from childbirth is remarkably rare, according to a study from the January issue of Anesthesiology. Additionally, in a second study, researchers at Wake Forest School of Medicine, Winston-Salem, N.C., found the biologic changes after delivery may prevent the development of pain.

19 Dec 2012

Ion channel acts as powerful ‘brake’ after epileptic seizures

Given that epilepsy impacts more than 2 million Americans, there is a pressing need for new therapies to prevent this disabling neurological disorder. New findings from the neuroscience laboratory of Mark S. Shapiro, Ph.D., at The University of Texas Health Science Center at San Antonio, published Dec. 20 in the high-impact scientific journal, Neuron, may provide hope.

19 Dec 2012

Kids misuse holiday baking ingredients for drug-like effect

Watch your kitchen cupboards this season as thrillseekers look to common holiday baking ingredients for a rise - cinnamon, nutmeg and even marshmallows are the primary ingredient in trendy risky behavior.

19 Dec 2012

High AngII levels put stress on the ER and cause hypertension

When the heart works too hard, the brain may be to blame, says new Cornell University research that is changing how scientists look at high blood pressure (hypertension). The study, published in the Journal of Clinical Investigation in November, traces hypertension to a newfound cellular source in the brain and shows that treatments targeting this area can reverse the disease.

18 Dec 2012

University of North Carolina awards 13th Perl prize to two NTNU-Trondheim scientists

The University of North Carolina at Chapel Hill has awarded the 13th Perl-UNC Neuroscience prize jointly to Edvard and May-Britt Moser at the Norwegian University of Science and Technology (NTNU-Trondheim) in Trondheim, Norway.

17 Dec 2012

Glutamate linked to suicidal behavior

Researchers have found the first proof that a chemical in the brain called glutamate is linked to suicidal behavior, offering new hope for efforts to prevent people from taking their own lives.

15 Dec 2012

Cedars-Sinai physician-scientist receives grant to study Charcot-Marie-Tooth disease

A Cedars-Sinai physician-scientist has been awarded a $3 million grant from the California Institute for Regenerative Medicine to study with new stem cell technology Charcot-Marie-Tooth disease, the most common inherited neurological disorder and which damages nerves that control muscles.

14 Dec 2012

Cedars-Sinai scientist to study Charcot-Marie-Tooth disease

14 Dec 2012

TUBB5 gene responsible for microcephaly: IMP study

Neurobiologists at the Research institute of Molecular Pathology (IMP) in Vienna have discovered one of the key genes required to make a brain. Mutations in this gene, called TUBB5, cause neurodevelopmental disease in children.

14 Dec 2012

Fingolimod associated with modest, rapid increase in macular volume

Patients with multiple sclerosis treated with fingolimod undergo a modest but rapid increase in macular volume, research shows.

13 Dec 2012

Skin vibrations convey information to the brain much the same way as auditory system

When you walk into a darkened room, your first instinct is to feel around for a light switch. You slide your hand along the wall, feeling the transition from the doorframe to the painted drywall, and then up and down until you find the metal or plastic plate of the switch. During the process you use your sense of touch to develop an image in your mind of the wall's surface and make a better guess for where the switch is.

12 Dec 2012

Viewpoints: Sen. Portman's Rx for deficit talks; Gerson says Obama needs to give Boehner political cover to make a deal

Washington needs to pursue structural reforms in the country's important but unsustainable entitlement programs and in an inefficient, outdated tax code. By doing so, lawmakers can responsibly avoid the immediate cliff while addressing the long-term fiscal crisis and spurring job creation.

12 Dec 2012