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RCas9 gene therapy clears toxic RNA buildup in mouse model of myotonic dystrophy

Myotonic dystrophy type I is the most common type of adult-onset muscular dystrophy. People with the condition inherit repeated DNA segments that lead to the toxic buildup of repetitive RNA, the messenger that carries a gene's recipe to the cell's protein-making machinery.

14 Sep 2020

Combining nanotechnology with immunotherapy to fight deadly metastatic breast cancer

A team of scientists led by a researcher at the Case Western Reserve University School of Medicine is making strides to fight deadly metastatic breast cancer by combining nanotechnology with immunotherapy.

14 Sep 2020

HSC researchers win NIH grant to expand innovative research into Alzheimer's disease

Researchers at HSC Fort Worth were awarded a grant expected to total $45 million from the National Institute on Aging, part of the National Institutes of Health, to expand innovative research into Alzheimer's disease and the biological differences that cause the disease to disproportionately afflict Mexican Americans.

14 Sep 2020

Immune system study helps illuminate a surprising mind-body connection

New research at Washington University School of Medicine in St. Louis helps illuminate a surprising mind-body connection.

14 Sep 2020

Rheumatology providers and patient advocates urge lawmakers to address healthcare challenges

The American College of Rheumatology will hold its first virtual Advocates for Arthritis event on Tuesday, Sept. 15, where more than 120 rheumatologists, rheumatology health professionals, and patient advocates will meet with lawmakers via video to discuss the healthcare challenges they are facing in the midst of COVID-19.

14 Sep 2020

Research provides insight into how muscles and fat tissue communicate to improve fitness

Why does exercise training make you more fit? It's well established that exercising enhances insulin sensitivity and improves our metabolism that, in turn, increases exercise performance. But the biological mechanisms underlying this adaptation are not fully understood.

14 Sep 2020

SMART researchers discover a new way to manufacture human red blood cells

Researchers from Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have discovered a new way to manufacture human red blood cells (RBCs) that cuts the culture time by half compared to existing methods and uses novel sorting and purification methods that are faster, more precise and less costly.

14 Sep 2020

RUDN geneticist finds a bifidobacterial protein that can reduce inflammation in COVID-19

A geneticist from RUDN University studied the effect of Bifidobacterium (intestinal bacteria) on the inflammatory process and discovered that their surface protein is capable of stopping excessive or uncontrollable inflammation, like the one observed in COVID-19 patients.

14 Sep 2020

NIH awards $26.56 million grant to create new Framingham Heart Study Brain Aging Program

Since 1976, the Framingham Heart Study (FHS)--the longest running multi-generational epidemiological study in the world--has followed participants for incident dementia.

14 Sep 2020

3D bioengineered model could reveal new treatments for deadly lung disease

A 3D bioengineered model of lung tissue built by University of Michigan researchers is poking holes in decades worth of flat, Petri dish observations into how the deadly disease pulmonary fibrosis progresses.

14 Sep 2020

Researchers receive $2.5 million grant to develop and analyze breast tumor organoids

Breast cancer is the second most common cancer diagnosed in women in the United States after skin cancer, and women with comorbidities (the presence of more than one condition/disease) often fare worse in terms of their breast cancer.

14 Sep 2020

Georgetown experts release report on pandemic preparedness and COVID-19 lessons

In a new report commissioned by the Global Preparedness Monitoring Board (GPMB), Georgetown global health experts say the success of any effort to redress pandemic preparedness failures demonstrated by COVID-19 requires a re-centering of governance that would include greater accountability, transparency, equity, participation and the rule of law.

14 Sep 2020

Researchers find coping techniques linked with positive mental health during COVID-19

The early days of the COVID-19 pandemic contributed to negative mental health effects for many in the U.S., according to new Penn State research. But the researchers also found that some coping techniques -- like wearing masks and focusing on self-care -- were linked with positive mental health.

14 Sep 2020

Tiny antibody component shows high potency in SARS-CoV-2 animal models

University of Pittsburgh School of Medicine scientists have isolated the smallest biological molecule to date that completely and specifically neutralizes the SARS-CoV-2 virus, which is the cause of COVID-19.

14 Sep 2020

IU School of Medicine and partners receive funding to deploy collaborative dementia care model

Supported by a $1.3 million grant from the U.S. Administration for Community Living, Department of Health and Human Services, Indiana University School of Medicine and its partners have launched a 36-month venture to enhance, strengthen and expand supports for people with Alzheimer's Disease and Related Dementias (ADRD) and their caregivers in 34 Indiana counties.

14 Sep 2020

Circadian rhythm affects SARS-CoV-2 infection and host immune response

In an interesting bioRxiv preprint paper, French researchers show that the time day can affect infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as guide subsequent host immune response – implying that circadian rhythm may well be a novel target for managing viral progression.

14 Sep 2020

Research News and Research

RCas9 gene therapy clears toxic RNA buildup in mouse model of myotonic dystrophy

Combining nanotechnology with immunotherapy to fight deadly metastatic breast cancer

HSC researchers win NIH grant to expand innovative research into Alzheimer's disease

Immune system study helps illuminate a surprising mind-body connection

Rheumatology providers and patient advocates urge lawmakers to address healthcare challenges

Research provides insight into how muscles and fat tissue communicate to improve fitness

SMART researchers discover a new way to manufacture human red blood cells

RUDN geneticist finds a bifidobacterial protein that can reduce inflammation in COVID-19

NIH awards $26.56 million grant to create new Framingham Heart Study Brain Aging Program

3D bioengineered model could reveal new treatments for deadly lung disease

Researchers receive $2.5 million grant to develop and analyze breast tumor organoids

Georgetown experts release report on pandemic preparedness and COVID-19 lessons

Researchers find coping techniques linked with positive mental health during COVID-19

Tiny antibody component shows high potency in SARS-CoV-2 animal models

IU School of Medicine and partners receive funding to deploy collaborative dementia care model

Circadian rhythm affects SARS-CoV-2 infection and host immune response

Drug for liver cirrhosis shows potential to treat dementia and motor neuron disease

Research finds genetic factors that protect from chronification of migraines

Earlier treatment with steroids reduces adverse outcomes in patients with septic shock

Phosphate binder drug does not reduce heart disease risk in people with chronic kidney disease

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