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T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Researchers characterized humoral and SARS-CoV-2 S-specific T cell responses in IBD patients who received two-dose mRNA-based COVID-19 vaccination series.

25 Feb 2022

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection.

24 Feb 2022

Melatonin as a safe and potentially life-saving treatment for COVID-19

A new study discusses the possible role of melatonin, an antioxidant and anti-inflammatory agent, in treating COVID-19.

24 Feb 2022

Advanced gene therapy may prevent severe loss of muscle mass in elderly people

Researchers at NTNU have managed to restore muscle function in older mice with muscle loss using advanced gene therapy. The hope is that this method might eventually be used on humans to prevent severe loss of muscle mass.

24 Feb 2022

Genetic analysis reveals eosinophilic colitis as a unique disease

A condition called eosinophilic colitis is distinct from other, similar eosinophilic gastrointestinal diseases and inflammatory bowel disease, according to a genetic analysis published in Gastroenterology.

24 Feb 2022

Metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 Delta, Alpha, and Omicron variants

Researchers examined how SARS-CoV-2 variants of concern differentially use an additional metalloproteinase-dependent entry pathway to enter the host cells.

24 Feb 2022

Study examines the effect of sevoflurane on sleep disturbance caused by systemic inflammation

Getting a good night's sleep can sometimes be a challenge, but inflammation may make it even more difficult.

24 Feb 2022

Novel AI tool can spot difficult-to-diagnose cardiac conditions

Physician-scientists in the Smidt Heart Institute at Cedars-Sinai have created an artificial intelligence (AI) tool that can effectively identify and distinguish between two life-threatening heart conditions that are often easy to miss: hypertrophic cardiomyopathy and cardiac amyloidosis.

23 Feb 2022

Large study funded by $33.1 million grant focuses on risk and resilience in the aging brain

A large study that investigates just what keeps our brains sharp as we age and what contributes to cognitive decline has been launched by researchers from Washington University School of Medicine in St. Louis, Harvard University/Massachusetts General Hospital, the University of Minnesota Medical School and the University of California Los Angeles.

23 Feb 2022

White blood cell count as a prognostic indicator of COVID-19

Based on a new study, researchers concluded WBC count variations worsen clinical outcomes such as severity, mortality, and hospital discharge rates leading to a poorer prognosis in COVID-19 patients.

23 Feb 2022

Study explores the impact of COVID-19 on pancreatic cells

New study findings showed that SARS-CoV-2 caused a productive yet restricted infection of pancreatic islet cells and an insignificant inflammatory response.

23 Feb 2022

Why is it Important to Democratize Proteomics Data?

In this interview, we speak to Steve Kosteski from IsoPlexis about the importance of single-cell proteomics within the life sciences sector.

From Society for Laboratory Automation and Screening (SLAS) 23 Feb 2022

EULAR develops new recommendations for cardiovascular risk management

EULAR, the European Alliance of Associations for Rheumatology, has developed new recommendations for CVR management in people with gout, vasculitis, systemic sclerosis (SSc), myositis, mixed connective tissue disease (MCTD), Sjögren's syndrome (SS), systemic lupus erythematosus (SLE), and antiphospholipid syndrome (APS).

23 Feb 2022