Therapy News and Research

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ADHD drug could serve as a cocaine-replacement therapy

Cocaine use continues to be a public health problem, yet despite concerted efforts, no drugs have been approved to resolve cocaine addiction. Research suggests that the attention-deficit/hyperactivity disorder drug methylphenidate (MPH; Ritalin) could serve as a cocaine-replacement therapy, but clinical results have been mixed.

30 Aug 2023

Study finds potential HIV cure using existing cancer drug

An existing blood cancer drug has shown promise in killing 'silent' HIV cells and delaying reinfections – a significant pre-clinical discovery that could lead to a future cure for the disease.

30 Aug 2023

Man-made antibody successfully prevents organ rejection after transplantation

A man-made antibody successfully prevented organ rejection when tested in primates that had undergone a kidney transplant, Duke Health researchers report.

30 Aug 2023

New oral agent shows promise in treatment of relapsed multiple myeloma

A new agent that subverts myeloma cells from within while also subjecting them to an immune system attack produced impressive responses in combination with dexamethasone in patients with multiple myeloma that had relapsed and stopped responding to all currently available therapies, a clinical trial conducted by researchers at Dana-Farber Cancer Institute and around the world has found.

30 Aug 2023

New mechanism of action discovered for pulmonary distress in immunocompromised patients

When an immunocompromised person's system begins to recover and produce more white blood cells, it's usually a good thing – unless they develop a potentially deadly inflammatory condition.

30 Aug 2023

Exercise may help improve sexual function in prostate cancer patients

Prostate cancer is one of the most common forms of cancer in the world, but not only does it put the lives of those diagnosed at risk, but can also severely impact patient quality of life due to side-effects of treatment.

30 Aug 2023

Low-carbohydrate diets as strategies for improving glycemic control in diabetic patients

Researchers evaluated the impact of low-carbohydrate diets on glycemic regulation among individuals with diabetes mellitus type 2.

30 Aug 2023

A move to cut drug prices has patients with rare diseases worried

For people with cystic fibrosis, like Sabrina Walker, Trikafta has been a life-changer.

30 Aug 2023

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

Researchers evaluated the tolerability, safety, pharmacodynamics, and pharmacokinetic properties of muvalaplin.

30 Aug 2023

An array of early psychological therapies in response to traumatic childbirth may buffer PTSD development

Researchers systematically reviewed and quantitatively assessed clinical trials on preventing Childbirth-Related Post-Traumatic Stress Disorder.

30 Aug 2023

Floatation therapy may be a novel treatment for anorexia nervosa

A trailblazing study conducted by researchers at the Laureate Institute for Brain Research (LIBR) in Tulsa, Okla., has made significant strides with a novel technique for treating anorexia nervosa (AN), an eating disorder characterized by low body weight, body image abnormalities, and anxiety.

29 Aug 2023

Light-driven bacteria could be used to target and kill cancer cells

Targeting malignant tumors with high precision is challenging for biomedical researchers. However, this scenario is likely to witness a paradigm shift in the near future, through the use of specially engineered bacteria, that can eliminate malignant cells efficiently.

29 Aug 2023

Gene therapy reduces hearing loss associated with Norrie disease in mice

An international team led by researchers at UCL and the NIHR Great Ormond Street Hospital Biomedical Research Centre have developed in mice a gene therapy that significantly reduces the hearing loss associated with Norrie disease.

29 Aug 2023

Drug-encapsulated nanogels show potential for treating obesity and other liver diseases

A University of Massachusetts Amherst biomedical engineer has used a nanogel-based carrier designed in his lab to deliver a drug exclusively to the liver of obese mice, effectively reversing their diet-induced disease.

29 Aug 2023

Natriuresis-guided diuretic therapy improves decongestion in acute heart failure

A pragmatic natriuresis-guided diuretic approach in patients with acute heart failure significantly increases 24-hour natriuresis without impacting all-cause mortality or heart failure rehospitalization, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Extended P2Y12 inhibitor monotherapy reduces bleeding and ischemic events in ACS patients

Extended P2Y12 inhibitor monotherapy beyond 12 months after percutaneous coronary intervention (PCI) reduces bleeding and ischemic events in acute coronary syndrome (ACS) patients at high risk for both types of events.

29 Aug 2023

Early initiation of dapagliflozin in acute decompensated heart failure does not improve diuretic efficiency

Early initiation of the sodium glucose co-transporter 2 (SGLT2) inhibitor dapagliflozin did not result in a statistically significant improvement in diuretic efficiency relative to structured usual care in hospitalized patients with acute decompensated heart failure (ADHF), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Longer duration of anticoagulation therapy benefits cancer patients with isolated distal DVT

Twelve months of edoxaban is superior to three months for the reduction of thrombotic events in patients with cancer and distal deep vein thrombosis (DVT), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

£5 million awarded to 12 projects aimed at tackling fatal drug overdoses

12 projects awarded a share of £5 million to reduce rates of fatal drug overdoses, as part of Vaccine Taskforce style approach to tackle health challenges.

29 Aug 2023

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Researchers investigated whether bone marrow-derived cells contribute to colitis-associated colon cancer.

29 Aug 2023

Therapy News and Research

ADHD drug could serve as a cocaine-replacement therapy

Study finds potential HIV cure using existing cancer drug

Man-made antibody successfully prevents organ rejection after transplantation

New oral agent shows promise in treatment of relapsed multiple myeloma

New mechanism of action discovered for pulmonary distress in immunocompromised patients

Exercise may help improve sexual function in prostate cancer patients

Low-carbohydrate diets as strategies for improving glycemic control in diabetic patients

A move to cut drug prices has patients with rare diseases worried

Can muvalaplin achieve safe and tolerable plasma concentrations adequate to reduce steady-state Lp(a) levels without modulating plasminogen activity in humans?

An array of early psychological therapies in response to traumatic childbirth may buffer PTSD development

Floatation therapy may be a novel treatment for anorexia nervosa

Light-driven bacteria could be used to target and kill cancer cells

Gene therapy reduces hearing loss associated with Norrie disease in mice

Drug-encapsulated nanogels show potential for treating obesity and other liver diseases

Natriuresis-guided diuretic therapy improves decongestion in acute heart failure

Extended P2Y12 inhibitor monotherapy reduces bleeding and ischemic events in ACS patients

Early initiation of dapagliflozin in acute decompensated heart failure does not improve diuretic efficiency

Longer duration of anticoagulation therapy benefits cancer patients with isolated distal DVT

£5 million awarded to 12 projects aimed at tackling fatal drug overdoses

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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