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Comprehensive analysis of antibody responses in COVID-19 patients can help develop effective vaccine

A comprehensive analysis of antibody responses in coronavirus disease 2019 (COVID-19) patients could inform the development of an effective vaccine, according to a study published September 10 in the open-access journal PLOS Pathogens by Chao Wu and Rui Huang of Nanjing University Medical School, and colleagues.

11 Sep 2020

Antibiotic molecule helps the body's own immune system to kill HIV infected cells

Ever since the first cases of a mysterious disease in the early 1980s exploded into the HIV/AIDS pandemic, researchers have been searching for ways to outsmart the deadly virus.

11 Sep 2020

Daily outdoor lessons in green spaces can boost self-regulation in young children

Amid one of the strangest back-to-school seasons in modern history, many teachers, parents, and caregivers are struggling to enrich their students' experiences beyond screen-based learning.

11 Sep 2020

Study highlights the importance of considering strain differences when designing therapies

Interferon (IFN) responses are one of the first defenses the body mounts against viral infections, and research has shown that it plays a role controlling viral replication.

11 Sep 2020

Study sheds light on the disproportionate impact of COVID-19

As the first wave of the COVID-19 pandemic was receding in mid-May, some 1.3 million working-age adults reported being home sick with symptoms they attributed to the coronavirus.

11 Sep 2020

New book gives overview of viruses and how they emerge to cause pandemics

Since the novel coronavirus SARS-Cov-2 emerged late last year, it has been virtually impossible to consume any news without encountering stories about the virus and how it spreads, potential treatments, and the development of new vaccines.

11 Sep 2020

Portable, low-field MRI device can be safely used at patient bedside, shows study

A portable, low-field magnetic resonance imaging (MRI) device can be safely used at bedside in complex clinical care settings to evaluate critically-ill patients for suspected stroke, traumatic brain injury (TBI), or other neurological problems, results of a proof-of-concept study show.

11 Sep 2020

Systematic efforts and clear structure are crucial for person-centered care

Systematic efforts and a clear structure are decisive factors in the transition to person-centred health care. A University of Gothenburg study, published in the scientific journal BMJ, reflects what is now a decade of experience and research in the field.

11 Sep 2020

Effective, simple, safe self-amplifying RNA vaccines

A recent review paper in the journal Current Opinion in Virology in September 2020 shows how a new generation of RNA vaccines called self-amplifying RNA vaccines are more potent than conventional mRNA vaccines and could hold the key to the global production of cost-effective potent COVID-19 vaccines.

11 Sep 2020

New study brings researchers closer to a universal COVID-19 antibody test

A new study released by Houston Methodist takes researchers a significant step closer to developing a uniform, universal COVID-19 antibody test.

11 Sep 2020

Researchers explore IgA response to SARS-CoV-2

A new study published on the preprint server bioRxiv* and conducted by researchers from The Rockefeller University in New York examined the role of IgA antibodies in preventing SARS-CoV-2 infection. In this study, the team analyzed the IgA response to SARS-CoV-2 infection in 149 individuals.

10 Sep 2020

Nonharmful stress promotes disease resilience in offspring, shows study

Research led by Jeff Gidday, PhD, Professor of Ophthalmology, Biochemistry, Neuroscience, and Physiology at LSU Health New Orleans School of Medicine, reports what is believed to be the first study in a mammalian model documenting the reprogramming of heritability to promote disease resilience in the next generation.

10 Sep 2020

Bedrails, door handles and ECG monitors hotspots for SARS-CoV-2 in hospital wards

A new study published in the journal Science of The Total Environment in September 2020 reports that the virus can be detected rapidly using already available technology, which will help to monitor viral spread within healthcare facilities more closely and enable better control of the pandemic.

10 Sep 2020

Male circumcision campaigns to reduce HIV transmission in Africa are based on systemic racism

World Health Organization-recommended campaigns to circumcise millions of African boys and men to reduce HIV transmission are based more on systemic racism and 'neocolonialism' than sound scientific research, according to a critical appraisal published in Developing World Bioethics.

10 Sep 2020

High blood pressure awareness and control worsening in the U.S.

Published in the journal JAMA, the study finds that a growing percentage of adults in the United States have uncontrolled high blood pressure, which is known as the “silent killer” and a significant risk factor for severe illness from the coronavirus disease (COVID-19).

10 Sep 2020

'One size fits all' clinical decision support systems not effective in reducing antibiotic prescriptions

Researchers at the University of Colorado College of Nursing at the Anschutz Medical Campus found that a unique set of factors of the emergency department (ED) makes standard Clinical Decision Support (CDS) systems not as effective in helping to reduce antibiotic overprescribing in that environment.

10 Sep 2020

People's emotion vocabulary indicates overall well-being

Vocabulary that one uses to describe their emotions is an indicator of mental and physical health and overall well-being, according to an analysis led by a scientist at the University of Pittsburgh School of Medicine and published today in Nature Communications.

10 Sep 2020

Study sheds light on how interferon-gamma drives response to immunotherapy in melanoma

A new study by researchers at the UCLA Jonsson Comprehensive Cancer Center sheds light on how interferon-gamma (IFN-y), an immune response-stimulating signaling molecule that helps activate immune cells, guides the treatment response in people with advanced melanoma who are treated with one of the leading immunotherapies - immune checkpoint blockade.

10 Sep 2020

Binge-drinkers have to put more effort to feel empathy for other people in pain

People who binge-drink show more extensive dysfunction across their brains than previously realized, a new study from the University of Sussex has shown.

10 Sep 2020

DLnano-vaccines may be a promising strategy for cancer immunotherapy

Researchers designed DLnano-vaccines displaying 60 copies of protein parts derived from the melanoma-specific antigens Trp2 and Gp100 and tested these in mouse models of melanoma, observing prolonged survival that depended on CD8 T cell activation both in therapeutic and prophylactic settings.

10 Sep 2020

Research News and Research

Comprehensive analysis of antibody responses in COVID-19 patients can help develop effective vaccine

Antibiotic molecule helps the body's own immune system to kill HIV infected cells

Daily outdoor lessons in green spaces can boost self-regulation in young children

Study highlights the importance of considering strain differences when designing therapies

Study sheds light on the disproportionate impact of COVID-19

New book gives overview of viruses and how they emerge to cause pandemics

Portable, low-field MRI device can be safely used at patient bedside, shows study

Systematic efforts and clear structure are crucial for person-centered care

Effective, simple, safe self-amplifying RNA vaccines

New study brings researchers closer to a universal COVID-19 antibody test

Researchers explore IgA response to SARS-CoV-2

Nonharmful stress promotes disease resilience in offspring, shows study

Bedrails, door handles and ECG monitors hotspots for SARS-CoV-2 in hospital wards

Male circumcision campaigns to reduce HIV transmission in Africa are based on systemic racism

High blood pressure awareness and control worsening in the U.S.

'One size fits all' clinical decision support systems not effective in reducing antibiotic prescriptions

People's emotion vocabulary indicates overall well-being

Study sheds light on how interferon-gamma drives response to immunotherapy in melanoma

Binge-drinkers have to put more effort to feel empathy for other people in pain

DLnano-vaccines may be a promising strategy for cancer immunotherapy

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