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Study shows SARS-CoV-2 cell receptor is a novel target of the gamma-secretase enzyme complex

Based on structural similarities with other targets of the gamma-secretase system, researchers from Columbia University Irving Medical Center in the United States show that the SARS-CoV-2 receptor for cell entry may be affected by its proteolytic activity. Their results are currently freely available in a bioRxiv preprint paper.

6 Sep 2020

Antibody responses against seasonal common cold coronaviruses may protect against SARS-CoV-2

With the use of an accurate high throughput assay, researchers from the Weizmann Institute of Science and Magen David Adom Blood Services in Israel showed substantial inter-individual variability and antibody cross-reactivity against seasonal coronaviruses upon SARS-CoV-2 infection, with important implications for immune surveys and vaccines. The study is currently available on the medRxiv* preprint server.

6 Sep 2020

Transparent Government builds trust and successful COVID-19 containment

The combined impact of the pandemic and these non-pharmaceutical interventions (NPIs) has taken a heavy toll on society, and this has led to much discussion as to the relative merits of these measures. A recent study published on the preprint server medRxiv in September 2020 shows that public trust is vital for the success of any such intervention.

6 Sep 2020

Twitter-propagated COVID-19 misinformation from credible sources has a huge impact

In March, in the early days of the coronavirus pandemic in Europe, a tweet from the French Health Minister, Olivier Verán, advised patients with COVID-19 not to take ibuprofen, an anti-inflammatory drug with analgesic and antipyretic properties.

5 Sep 2020

Monitoring the activity of unconventional T cells could predict COVID-19 severity

Researchers in France have discovered that patients suffering from severe COVID-19 show changes in a class of immune cells known as unconventional T cells.

5 Sep 2020

MIS-C linked to COVID-19 damages children's hearts

Multisystem inflammatory syndrome in children (MIS-C), believed to be linked to COVID-19, damages the heart to such an extent that some children will need lifelong monitoring and interventions, said the senior author of a medical literature review published Sept. 4 in EClinicalMedicine, a journal of The Lancet.

5 Sep 2020

Mason researchers to provide biostatistics and bioinformatic analysis for new project

Virginia Espina, Research Associate Professor, Applied Proteomics and Molecular Medicine, received $21,000 from Baylor Research Institute for a project in which Mason researchers are providing biostatistics and bioinformatic analysis for integrating multi-omic data sets from a breast cancer cohort.

5 Sep 2020

Study may provide the basis for better diagnostic, therapeutic approaches to blood diseases

The hemoglobin in the red blood cells ensures that our body cells receive sufficient oxygen. When the blood pigment is broken down, "heme" is produced, which in turn can influence the protein cocktail in the blood.

5 Sep 2020

Common class of drugs may be associated with increased risk of cognitive decline

A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad array of conditions, from allergies and colds to hypertension and urinary incontinence, may be associated with an increased risk of cognitive decline, particularly in older adults at greater risk for Alzheimer's disease.

5 Sep 2020

IU researcher receives NCI grant to study side effects of cancer treatment

A researcher at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center has been awarded a five-year, $5.7 million National Cancer Institute grant to evaluate long-term health outcomes for cancer patients who receive platinum-based chemotherapies.

5 Sep 2020

Maternal dietary imbalance triggers overeating in mice offspring

Pregnant mice fed a diet high in omega-6 fats and low in omega-3 fats produce offspring that go on to exhibit "hedonic"--pleasurable but excessive--levels of consumption of hyper-caloric diets, according to researchers at Hiroshima University.

5 Sep 2020

Tailored obesity intervention program offers hope for weight loss in underserved patients

Low-income Louisiana patients enrolled in a tailored obesity intervention program lost much more weight than counterparts receiving usual care. Study results were published this week in The New England Journal of Medicine.

5 Sep 2020

Patient priorities for optimal transplant and living donor advocacy during COVID-19 and beyond

In a newly published paper, the authors first paint the vision of what optimal patient advocacy can do to overcome the challenges described by kidney transplant patients and donors and then describe how to make that vision a reality, especially during the COVID-19 pandemic.

5 Sep 2020

Activation of fatty acid receptor causes masculinization of Japanese rice fish

A research collaboration based at Kumamoto University (Japan) has found that activation of PPARα, a fatty acid receptor that detects fatty acids in cells and regulates physiological functions, causes masculinization of Japanese rice fish (medaka).

5 Sep 2020

Study addresses evolutionary rates of larval and adult life stages at a large scale

If you have any children in your life, imagine for a moment that they don't look anything like their parents, they don't eat anything humans normally eat, and they're active only while adults sleep.

5 Sep 2020

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Results from two early-phase Russian non-randomised vaccine trials (Sputnik V) in a total of 76 people are published today in The Lancet, finding that two formulations of a two-part vaccine have a good safety profile with no serious adverse events detected over 42 days, and induce antibody responses in all participants within 21 days.

5 Sep 2020

Research News and Research

Study shows SARS-CoV-2 cell receptor is a novel target of the gamma-secretase enzyme complex

Antibody responses against seasonal common cold coronaviruses may protect against SARS-CoV-2

Transparent Government builds trust and successful COVID-19 containment

Twitter-propagated COVID-19 misinformation from credible sources has a huge impact

Monitoring the activity of unconventional T cells could predict COVID-19 severity

MIS-C linked to COVID-19 damages children's hearts

Mason researchers to provide biostatistics and bioinformatic analysis for new project

Study may provide the basis for better diagnostic, therapeutic approaches to blood diseases

Common class of drugs may be associated with increased risk of cognitive decline

IU researcher receives NCI grant to study side effects of cancer treatment

Maternal dietary imbalance triggers overeating in mice offspring

Tailored obesity intervention program offers hope for weight loss in underserved patients

Patient priorities for optimal transplant and living donor advocacy during COVID-19 and beyond

Activation of fatty acid receptor causes masculinization of Japanese rice fish

Study addresses evolutionary rates of larval and adult life stages at a large scale

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

New project to increase provision for trauma and emergency care in Zambia during COVID-19 pandemic

Historical case studies: Pandemics in past societies

Two researchers from Bielefeld University receive ERC Starting Grants

Study unravels why people with knee osteoarthritis experience varying pain patterns

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