Inflammation News and Research

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Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

Researchers investigated the role of platelets in the adverse immune response against a COVID-19 vaccine.

16 Feb 2022

The long-term consequences of SARS-CoV-2 infection in people with HIV

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from the United States (US) analyzed a cohort of patients with human immunodeficiency virus (HIV) (PWH) recovering from coronavirus disease 2019 (COVID-19) and characterized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immune responses in these patients.

15 Feb 2022

Stem cell infusion improves the survival of mice with sepsis

A one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis, shows a study published today in eLife.

15 Feb 2022

Study uncovers most critical genes that cause coronary heart disease

The most critical genes that cause coronary heart disease and trigger heart attacks have been identified in a major new study.

15 Feb 2022

Cardiac MRI shows a similar injury pattern for vaccine-associated myocarditis

Vaccine-associated myocarditis shows a similar injury pattern on cardiac MRI compared to other causes of myocarditis, but abnormalities are less severe, according to a new study published in the journal Radiology.

15 Feb 2022

Novel promising biomarker correlates with the severity of facioscapulohumeral muscular dystrophy

There is currently no effective treatment for facioscapulohumeral muscular dystrophy (FSHD), one of the most common neuromuscular diseases, which is caused by an abnormal expression of the transcription factor DUX4.

15 Feb 2022

New approach to alter the skin microbiome and reduce acne lesions using bacteria

Acne on the face is often treated with topical antibiotics, which tend to be used for an extended period of time and contribute to the serious problem of antibiotic resistance.

15 Feb 2022

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

A new study may provide a partial explanation for the long-term immunologic phenomena associated with COVID-19.

15 Feb 2022

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Single-cell RNA sequencing, or "scRNA-seq" for short, is a technique that allows scientists to study the expression of genes in an individual cell within a mixed population – which is virtually how all cells exist in the body's tissues.

15 Feb 2022

Regulating inflammation in Alzheimer's disease using a nanocleaner

In this new article publication from Acta Pharmaceutica Sinica B, authors Ting Lei, Zhihang Yang, Xue Xia, Yuxiu Chen, Xiaotong Yang, Rou Xie, Fan Tong, Xiaolin Wang, Huile Gao from Sichuan University, Chengdu, China and Macau University of Science and Technology, Macau, China discuss how nanocleaners can specifically penetrate the blood‒brain barrier at lesions to clean toxic proteins and regulate inflammation in Alzheimer's disease.

14 Feb 2022

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

A recent study posted to the bioRxiv* pre-print server investigated the antiviral potential of N-acylethanolamine acid amidase (NAAA) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the Zika virus (ZIKV).

14 Feb 2022

Research highlights the need to include diverse populations in immunogenetic studies

Disease and health are the result of a complex interaction between humans and their pathogens. Genetic factors that partly determine host defenses sometimes differ significantly between people and populations.

14 Feb 2022

Antihistamines may offer hope for long COVID patients

Researchers offer hope that an inexpensive over-the-counter medication could improve long COVID symptoms for a large proportion of these patients.

14 Feb 2022

Structural protein vimentin facilitates SARS-CoV-2 entry into endothelial cells

Researchers suggest that extracellular vimentin may act as a coreceptor to allow for SARS-CoV-2 entry into cells.

14 Feb 2022

Study identifies a link between mortality of newborns on ECMO and red blood cell transfusion volume

Newborns in respiratory failure who require the life-sustaining support of ECMO also require transfusion of red blood cells. But a new study indicates that the higher volume of these oxygen-carrying blood cells the babies receive, the higher their mortality rate.

14 Feb 2022

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

In a study posted to the bioRxiv* preprint server, a team of researchers from the United States evaluated the protective effect of the preclinical version of the current Moderna Omicron-targeted mRNA-1273.529 vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 Omicron infection in mice.

14 Feb 2022

Novel tool for better dietary management in cancer patients

A new dietary tool to quickly and accurately assess micronutrient levels aims to help cancer patients fight disease, paving the way to find better nutritional solutions for oncology services, Flinders University researchers say.

14 Feb 2022

Testes found to be a viral reservoir for SARS-CoV-2 replication

In a recent study posted to the medRxiv* pre-print server, researchers used a suite of methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the testis of patients who died from coronavirus disease 2019 (COVID-19) to gain insights into SARS-CoV-2 tropism inside testis and its impact on male fertility.

13 Feb 2022

Hollings researcher receives grant to fight complications after pediatric bone marrow transplant

MUSC Hollings Cancer Center researcher Sophie Paczesny, M.D., Ph.D., recently received a four-year grant from the National Heart, Lung, and Blood Institute to investigate solutions to help doctors to fight complications after pediatric bone marrow transplantation (BMT).

12 Feb 2022

Pharmacological manipulation could restore microglia function after exposure to industrial toxin in utero

New research shows that exposure to the industrial byproduct TCDD in utero could cause the brain's immune system to go array later in life, damaging important brain circuits, and potentially giving rise to neurodevelopmental disorders, such as autism and ADHD.

11 Feb 2022

Inflammation News and Research

Features of platelet-immune crosstalk in healthy recipients of two doses of mRNA-based SARS-CoV-2 vaccine BNT162b2

The long-term consequences of SARS-CoV-2 infection in people with HIV

Stem cell infusion improves the survival of mice with sepsis

Study uncovers most critical genes that cause coronary heart disease

Cardiac MRI shows a similar injury pattern for vaccine-associated myocarditis

Novel promising biomarker correlates with the severity of facioscapulohumeral muscular dystrophy

New approach to alter the skin microbiome and reduce acne lesions using bacteria

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Regulating inflammation in Alzheimer's disease using a nanocleaner

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

Research highlights the need to include diverse populations in immunogenetic studies

Antihistamines may offer hope for long COVID patients

Structural protein vimentin facilitates SARS-CoV-2 entry into endothelial cells

Study identifies a link between mortality of newborns on ECMO and red blood cell transfusion volume

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

Novel tool for better dietary management in cancer patients

Testes found to be a viral reservoir for SARS-CoV-2 replication

Hollings researcher receives grant to fight complications after pediatric bone marrow transplant

Pharmacological manipulation could restore microglia function after exposure to industrial toxin in utero

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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