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Researchers use silk fibers to grow stem cells into salivary gland cells

The silkworm, which produces the essential ingredient for fine silk fabric, also plays a critical role in a new process designed to provide relief for millions of individuals with dry mouth, a devastating oral and systemic health issue.

28 Jul 2015

Amgen announces submission of supplemental New Drug Application to FDA for Kyprolis (carfilzomib)

Amgen today announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration for Kyprolis (carfilzomib) for Injection to seek an expanded indication for the treatment of patients with a form of blood cancer, relapsed multiple myeloma, who have received at least one prior therapy.

23 Jul 2015

Heidelberg University scientists gain new insight into cytotoxic effect of Ebola virus

In the course of basic research in membrane biochemistry scientists at Heidelberg University have gained new insight into the cytotoxic effect of the Ebola virus. Employing biochemical and cell biological methods they have shed light on the molecular relationships between the Ebola glycoprotein and its role in mediating cytotoxicity.

22 Jul 2015

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

The Salk Institute today announced that Rusty Gage, Salk professor in the Laboratory of Genetics, has been selected as one of five recipients of the Paul G. Allen Family Foundation's Allen Distinguished Investigator (ADI) program and will be awarded $1.5 million to conduct his research. These researchers have projects aimed at uncovering the elusive biological foundations of Alzheimer's disease.

15 Jul 2015

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

The Paul G. Allen Family Foundation announced today the award of Allen Distinguished Investigator (ADI) grants to five teams of researchers with projects that will open new and innovative avenues of research in Alzheimer's disease by uncovering its elusive biological roots.

14 Jul 2015

UCSD researchers discover cell signaling pathway that controls initiation, progression of colorectal cancer

Researchers at University of California, San Diego School of Medicine have discovered a cell signaling pathway that appears to exert some control over initiation and progression of colorectal cancer, the third leading cause of cancer-related death in the United States. A key protein in the pathway also appears to be predictive of cancer survival rates.

1 Jul 2015

CMC Biologics expands North American manufacturing facility with addition of Bioreactor 6Pack facility

CMC Biologics, Inc., a global leader in clinical and commercial manufacturing of monoclonal antibodies and other therapeutic proteins, announced today that, as part of its global manufacturing capacity expansion strategy, it has completed the expansion of its North American manufacturing facility in Bothell, Washington with the addition of a single-use Bioreactor 6Pack™ facility.

30 Jun 2015

BIOCITECH, Seine-Saint-Denis CCI announce winners of first BIOCITECH Funding Day

BIOCITECH, the city complex for healthcare and biotechnology businesses and the Seine-Saint-Denis Chamber of Commerce and Industry (CCI), today announce the three winners of the first BIOCITECH Funding Day.

27 Jun 2015

New 3D cell culture system could facilitate search for therapeutic agents for Parkinson's disease

The progressive loss of neurons in the brain of Parkinson's patients is slow yet inexorable. So far, there are no drugs that can halt this insidious process.

25 Jun 2015

Gene-encoded protein may be effective in early detection of pancreatic cancer

A protein encoded by the gene glypican-1 (GPC1) present on cancer exosomes may be used as part of a potential non-invasive diagnostic and screening tool to detect early pancreatic cancer, potentially at a stage amenable to surgical treatment, according to a study at The University of Texas MD Anderson Cancer Center.

24 Jun 2015

Benitec, ReNeuron collaborate to launch new exploratory cellular therapy program

Benitec Biopharma is pleased to announce the launch of a new exploratory cellular therapy program including exosome-based delivery utilising the Company's proprietary ddRNAi technology. Entry into these areas have been facilitated by the commencement of a collaboration with UK-based stem cell therapeutics company, ReNeuron.

22 Jun 2015

Planning for first clinical trial of MERS-CoV vaccine candidate now underway

Researchers from Ludwig-Maximilians-Universitaet in Munich have demonstrated, in a preclinical setting, the protective effect of a candidate vaccine directed against the coronavirus that causes Middle East Respiratory Syndrome. Planning for the first clinical trial is now underway.

22 Jun 2015

Researchers explore the science of exosomes in heart repair

A little more than a decade ago, researchers discovered that all cells secrete tiny communications modules jammed with an entire work crew of messages for other cells. Today, a team of researchers, led by stem cell researcher Raj Kishore, PhD, Director of the Stem Cell Therapy Program at the Center for Translational Medicine at Temple University School of Medicine, is harnessing the communications vesicles excreted by stem cells and using them to induce the damaged heart to repair itself.

19 Jun 2015

Florida Institute finalizes funding agreement with TransGenex Nanobiotech

The Florida Institute for the Commercialization of Public Research announced today that it has finalized a funding agreement with TransGenex Nanobiotech, Inc., a company that is developing nano-scale technologies for novel, cost-effective diagnostic and therapeutic agents against cancers and other inflammatory diseases.

19 Jun 2015

$Phase 3 study shows Vectibix meets primary endpoint in patients with chemorefractory wild-type KRAS mCRC$

Phase 3 study shows Vectibix meets primary endpoint in patients with chemorefractory wild-type KRAS mCRC

Amgen today announced that a Phase 3 study evaluating Vectibix (panitumumab) and best supportive care (BSC) met its primary endpoint, demonstrating a statistically significant improvement in overall survival (OS) in patients with chemorefractory wild-type KRAS (exon 2) metastatic colorectal cancer (mCRC) compared to those patients treated with BSC alone.

19 Jun 2015

Study identifies new biomarkers for prenatal risk assessment

NX Prenatal Inc., a privately held women's healthcare molecular diagnostic company, announced today that the American Journal of Perinatology has published the results of a blinded, retrospective study of 48 asymptomatic, healthy pregnant women that demonstrates the feasibility of assessing biomarkers associated with blood based microvesicles/exosomes for spontaneous preterm birth (SPTB) risk.

18 Jun 2015

TSRI chemists invent scalable method for synthesizing brain-protecting compound

Chemists at The Scripps Research Institute have invented the first practical, scalable method for synthesizing jiadifenolide, a plant-derived molecule that may have powerful brain-protecting properties.

17 Jun 2015

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

CQDM and Ontario Centres of Excellence will fund five highly innovative and unconventional game-changing research and development projects to accelerate drug discovery in the Quebec-Ontario Life Sciences Corridor. Partners are granting $1.5M to Quebec-based and, for the first time, Ontario-based researchers thanks to the partnership with OCE through CQDM's 2014 Explore Program, one of CQDM's flagship programs focusing on early concept validation of cutting-edge technologies that address the most crucial needs in drug discovery and development.

17 Jun 2015

SynGenXTM-1000 System adopted by Anthony Nolan Cell Therapy Centre

SynGen Inc., a company that focuses on the development and commercialization of instrument systems that harvest stem and progenitor cells from umbilical cord blood, bone marrow, peripheral blood, and cell culture, announced today that, after extensive review of competitive systems, The Anthony Nolan Cell Therapy Centre in Nottingham UK has chosen the SynGenXTM-1000 System and the CryoPRO Workstation to process its umbilical cord blood units. Anthony Nolan has signed a 5-year contract with Deva Medical Electronics Ltd, SynGen Inc.’s UK distributor, for the supply of SynGen’s products and all post-sales support, starting late summer 2015.

15 Jun 2015

Early neuronal lysosomal dysfunction could help predict AD

Blood levels of altered lysosomal proteins may help detect preclinical Alzheimer’s disease, researchers report.

12 Jun 2015

Exosomes News and Research

Researchers use silk fibers to grow stem cells into salivary gland cells

Amgen announces submission of supplemental New Drug Application to FDA for Kyprolis (carfilzomib)

Heidelberg University scientists gain new insight into cytotoxic effect of Ebola virus

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

UCSD researchers discover cell signaling pathway that controls initiation, progression of colorectal cancer

CMC Biologics expands North American manufacturing facility with addition of Bioreactor 6Pack facility

BIOCITECH, Seine-Saint-Denis CCI announce winners of first BIOCITECH Funding Day

New 3D cell culture system could facilitate search for therapeutic agents for Parkinson's disease

Gene-encoded protein may be effective in early detection of pancreatic cancer

Benitec, ReNeuron collaborate to launch new exploratory cellular therapy program

Planning for first clinical trial of MERS-CoV vaccine candidate now underway

Researchers explore the science of exosomes in heart repair

Florida Institute finalizes funding agreement with TransGenex Nanobiotech

Phase 3 study shows Vectibix meets primary endpoint in patients with chemorefractory wild-type KRAS mCRC

Study identifies new biomarkers for prenatal risk assessment

TSRI chemists invent scalable method for synthesizing brain-protecting compound

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

SynGenXTM-1000 System adopted by Anthony Nolan Cell Therapy Centre

Early neuronal lysosomal dysfunction could help predict AD

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