Interferon News and Research

RSS

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

In severe Covid-19 patients, the metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order to fight the virus effectively.

28 Jul 2022

Highly specialized T cells remain in blood 20 months after COVID-19

researchers analyze T-cell reactivity following recovery from COVID-19.

27 Jul 2022

Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution

Researchers compared the potency of 17 human interferons (IFNs) against multiple SARS-CoV-2 variants.

27 Jul 2022

Study shows SARS-CoV-2 impairs interferon production through NSP2-induced repression of mRNA translation

Researchers discovered a SARS-CoV-2 non-structural protein 2 (NSP2)-mediated mechanism by which it suppresses the production of interferon-beta (IFN-β) in host cells.

27 Jul 2022

Scientists discover a surprising link between mitochondria, inflammation and DNMT3A and TET2 genes

Mitochondria are known as cells' powerhouses, but mounting evidence suggests they also play a role in inflammation. Scientists from the Salk Institute and UC San Diego published new findings in Immunity on July 26, 2022, where they examined human blood cells and discovered a surprising link between mitochondria, inflammation and DNMT3A and TET2 - two genes that normally help regulate blood cell growth but, when mutated, are associated with an increased risk of atherosclerosis.

26 Jul 2022

Scientists investigate how interferons interact with SARS-CoV-2 variants

Researchers at the University of Colorado Anschutz Medical Campus have investigated how antiviral proteins called interferons interact with SARS-CoV-2, the cause of COVID-19.

25 Jul 2022

Scientists identify papain-like protease inhibitor against COVID-19

In a new study, researchers identified a papain-like protease inhibitor for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

25 Jul 2022

Is monkeypox a global public-health emergency?

A summary of available knowledge on the monkeypox virus including pathogenicity, risk to the human population, and strategies that can help limit its spread.

20 Jul 2022

Scientists find a promising new combination therapy for certain types of lung tumors

Scientists at the Francis Crick Institute have found that using immunotherapy alongside a drug that blocks a common gene mutation in lung cancer could be a promising new combination therapy for certain types of lung tumors.

20 Jul 2022

Potential mRNA vaccines for influenza

Scientists discuss the benefits of shifting the global influenza vaccination system to a mRNA-based platform,

19 Jul 2022

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

Influence of chr12q24.13 domain on COVID-19 severity

Researchers evaluated the probable impact of the chr12q24.13 domain on the outcomes of laboratory-validated SARS-CoV-2 infection.

19 Jul 2022

Analyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cells

Researchers showed that the SARS-CoV-2 nucleocapsid (N) and spike (S) proteins did not activate γδ T cells and dendritic cells (DCs).

18 Jul 2022

The pathobiology, host response, and effects of SARS-CoV-2 on the respiratory and intestinal microbiome

Researchers investigated the effect of influenza A virus pre-exposure and SARS-CoV-2 infection in the elderly population using a 14-month-aged golden Syrian hamsters model.

18 Jul 2022

Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infection

A new study showed that 7DW8-5, an immunostimulatory glycolipid impeded three respiratory viral infections, including SARS-CoV-2, in vivo.

18 Jul 2022

Cytokine-based cancer immunotherapy: current progress and future prospects

In this interview, News-Medical talks to Dr. Shuang Zhou about cytokine-base cancer immunotherapy, the current state of the field, and future prospects.

From Sino Biological Inc. 18 Jul 2022

Study shows that older adults can generate robust, long-lived memory against SARS-CoV-2 following infection

Researchers reported on the benefit of immunity developed by previous SARS-CoV-2 infection for overcoming the age-associated decline in COVID-19 vaccine effectiveness.

18 Jul 2022

The potential of circular RNA COVID-19 vaccines

A new MedComm study describes the potential use of circular ribonucleic acid COVID-19 vaccines.

17 Jul 2022

Chemokine-DNA nanoparticles can induce chronic, dysfunctional immune responses

Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study by researchers at Weill Cornell Medicine and Hospital for Special Surgery (HSS).

15 Jul 2022

Minimally invasive skin biopsy can help assess tissue damage related to SARS-CoV-2 infection

Using skin biopsy samples, investigators found that patients with severe COVID-19 had clots in small venous and arterial blood vessels in skin that appears normal.

14 Jul 2022

Interferon News and Research

Study highlights impaired ketogenesis as a potential confounder of severe COVID-19

Highly specialized T cells remain in blood 20 months after COVID-19

Increased resistance to human interferons could be a potential driver of SARS-CoV-2 evolution

Study shows SARS-CoV-2 impairs interferon production through NSP2-induced repression of mRNA translation

Scientists discover a surprising link between mitochondria, inflammation and DNMT3A and TET2 genes

Scientists investigate how interferons interact with SARS-CoV-2 variants

Scientists identify papain-like protease inhibitor against COVID-19

Is monkeypox a global public-health emergency?

Scientists find a promising new combination therapy for certain types of lung tumors

Potential mRNA vaccines for influenza

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Influence of chr12q24.13 domain on COVID-19 severity

Analyzing whether SARS-CoV-2 nucleocapsid and spike proteins stimulate dendritic or γδ T cells

The pathobiology, host response, and effects of SARS-CoV-2 on the respiratory and intestinal microbiome

Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infection

Cytokine-based cancer immunotherapy: current progress and future prospects

Study shows that older adults can generate robust, long-lived memory against SARS-CoV-2 following infection

The potential of circular RNA COVID-19 vaccines

Chemokine-DNA nanoparticles can induce chronic, dysfunctional immune responses

Minimally invasive skin biopsy can help assess tissue damage related to SARS-CoV-2 infection

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Latest News