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Anthrax capsule vaccine offers protection from deadly anthrax infection in monkeys

Vaccination with the anthrax capsule--a naturally occurring component of the bacterium that causes the disease--completely protected monkeys from lethal anthrax infection, according to a study published online this week in the journal VACCINE.

27 Jun 2016

Scientists elucidate why acute leukemias with same genetic abnormality vary in aggressiveness

Scientists at the Friedrich Miescher Institute for Biomedical Research and the University of Basel have discovered why acute leukemias with the same genetic abnormality vary in their aggressiveness based on their cellular origin.

24 Jun 2016

Inflammatory response to mosquito bites can help spread viral infections

Mosquito bite sites are not just itchy, irritating nuisances - they also make viral infections spread by the insects far worse, new research has found.

22 Jun 2016

VUMC researchers aim to decode genetic underpinnings of human immune system

Researchers at Vanderbilt University Medical Center this month began recruiting volunteers to participate in a clinical trial aimed at decoding the human "immunome," the genetic underpinnings of the immune system.

22 Jun 2016

Salk Institute researchers use super-resolution microscope to image vital receptors in lymph nodes

When the body is fighting an invading pathogen, white blood cells--including T cells--must respond. Now, Salk Institute researchers have imaged how vital receptors on the surface of T cells bundle together when activated.

16 Jun 2016

IGF-1 protein may be key to prevent heart disease in older adults

As men and women grow older, their chances for coronary heart disease also increase. Atherosclerosis is a condition in which plaque builds up inside the arteries, which can lead to serious problems, including heart attacks, strokes or even death.

16 Jun 2016

Researchers find unexpected connection between two types of calming immune cells

Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit our guts pose a constant risk of infection--and all that separates us from these foreign entities is a delicate boundary made of a single layer of cells.

15 Jun 2016

Autologous stem cell transplant safe, effective for HIV-associated lymphoma patients

New research published online today in Blood Journal of the American Society of Hematology (ASH), challenges the generally held belief that individuals with HIV and aggressive lymphoma are not candidates for standard treatment.

14 Jun 2016

T memory cells with naive phenotype can help boost immunity in older adults

Sixty-five is the age when many people retire, kick back and take it easy. And so it often is with the human immune system.

14 Jun 2016

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors.

10 Jun 2016

Utah researchers find way to use power of protease to destroy budding AIDS virus

When new AIDS virus particles bud from an infected cell, an enzyme named protease activates to help the viruses mature and infect more cells. That's why modern AIDS drugs control the disease by inhibiting protease.

10 Jun 2016

New drug ixekizumab helps clear severe psoriasis symptoms

About 80 percent of patients with moderate to severe psoriasis saw their disease completely or almost completely cleared with a new drug called ixekizumab, according to three large, long-term clinical trials led by Northwestern Medicine.

10 Jun 2016

Simple blood test can help track rising levels of eosinophils linked to regrowth of sinus polyps

In an effort to identify a simple, reliable way to track the course of nasal polyps in chronic sinus disease, Johns Hopkins Medicine researchers say they've linked rising levels of immune system white blood cells, called eosinophils, with regrowth of polyps removed by surgery.

9 Jun 2016

Study provides new insights into development of skin-depigmenting disease vitiligo

Researchers at the University of Bonn and the Ludwig-Maximilians-Universität of Munich have decoded a new mechanism of how the immune system can specifically attack pigmented cells of the skin.

8 Jun 2016

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

A drug, more commonly used in the treatment of angina, could be the focus of a new strategy in fighting the fatal fungal infection cryptococcosis

8 Jun 2016

Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Researchers at the University of Cincinnati College of Medicine have found that adding increasing doses of an approved Type 2 diabetes drug, metformin, to a chemotherapy and radiation treatment regimen in head and neck cancer patients is not well tolerated if escalated too quickly, but allowing slower escalation could be beneficial.

6 Jun 2016

Nivolumab drug shows better response rate in metastatic bladder cancer patients

The immune checkpoint blockade drug nivolumab reduced tumor burden in 24.4 percent of patients with metastatic bladder cancer, regardless of whether their tumors had a biomarker related to the drug's target, according to clinical trial results from The University of Texas MD Anderson Cancer Center.

6 Jun 2016

HLA genetic risk burden extends to MS outcomes

Human leukocyte antigen alleles not only increase susceptibility to multiple sclerosis, but also influence the course of the disease, suggests research.

3 Jun 2016

Enzyme protein neutrophil elastase may be key contributor to development of muscular dystrophy

Scientists at the University of Liverpool have discovered that muscle cells affected by muscular dystrophy contain high levels of an enzyme that impairs muscle repair. This finding provides a new target for potential drug treatments for the disease, which currently has no cure.

2 Jun 2016

Slime mold provides key to understanding directional ability of immune cells

How white blood cells in our immune systems home in on and engulf bacterial invaders--like humans following the scent of oven-fresh pizza--has long been a mystery to scientists.

28 May 2016

Leukocyte News and Research

Anthrax capsule vaccine offers protection from deadly anthrax infection in monkeys

Scientists elucidate why acute leukemias with same genetic abnormality vary in aggressiveness

Inflammatory response to mosquito bites can help spread viral infections

VUMC researchers aim to decode genetic underpinnings of human immune system

Salk Institute researchers use super-resolution microscope to image vital receptors in lymph nodes

IGF-1 protein may be key to prevent heart disease in older adults

Researchers find unexpected connection between two types of calming immune cells

Autologous stem cell transplant safe, effective for HIV-associated lymphoma patients

T memory cells with naive phenotype can help boost immunity in older adults

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Utah researchers find way to use power of protease to destroy budding AIDS virus

New drug ixekizumab helps clear severe psoriasis symptoms

Simple blood test can help track rising levels of eosinophils linked to regrowth of sinus polyps

Study provides new insights into development of skin-depigmenting disease vitiligo

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients

Nivolumab drug shows better response rate in metastatic bladder cancer patients

HLA genetic risk burden extends to MS outcomes

Enzyme protein neutrophil elastase may be key contributor to development of muscular dystrophy

Slime mold provides key to understanding directional ability of immune cells

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