Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Thrasos presents positive results of THR-184 compound for treatment of acute kidney injury

Thrasos Therapeutics, a biotherapeutics company focused on delivering new solutions for kidney disease, today presented preclinical results showing that its lead development compound THR-184 can effectively protect against loss of kidney function following acute ischemic injury in rat.

4 Jun 2014

$Vitamin D with calcium can protect against risk of common bone fractures for seniors$

Vitamin D with calcium can protect against risk of common bone fractures for seniors

For seniors over the age of 65, taking a daily supplement of vitamin D with calcium—but not vitamin D alone—can offer some protection against the risk of common bone fractures, according to an updated review from The Cochrane Library.

4 Jun 2014

Findings could lead to treatments for blood disorders associated with iron deficiencies and overloads

A UCLA research team has discovered a new hormone called erythroferrone, which regulates the iron supply needed for red blood-cell production.

2 Jun 2014

Promedior reports positive preliminary data from PRM-151 Phase 2 trial for myelofibrosis

Promedior, Inc., today announced positive preliminary data from its Phase 2 trial of PRM-151, an anti-fibrotic immunotherapy, in patients with myelofibrosis which demonstrated biologic activity with improvements across clinically relevant measures, including bone marrow fibrosis, hemoglobin, platelets, spleen, and symptoms.

31 May 2014

Researchers create experimental blood test that determines BHI by gauging performance of mitochondria

Researchers at the University of Alabama at Birmingham School of Medicine have created an experimental blood test that, for the first time, determines a "Bioenergetic Health Index," or BHI, by gauging the performance of mitochondria, the cell's energy powerhouses.

30 May 2014

Reduced glomerular filtration rate is independent risk factor for renal and urothelial cancer

Researchers who investigated the level of kidney function and subsequent cancer risk in more than one million adults have found that reduced glomerular filtration rate (GFR) — a key measure of reduced kidney function and chronic kidney disease (CKD) — is an independent risk factor for renal and urothelial cancer but not other cancer types.

30 May 2014

People with diabetes have about double risk of premature death

People with diabetes have about double the risk of premature death as people of the same age without diabetes.

30 May 2014

Dialysis patients suffering from depression and anxiety have greatest impairments in physical exercise

With the rate of chronic kidney disease on the rise among older Americans, researchers seeking to improve patients' quality of life studied a group of adults undergoing hemodialysis and found their higher rates of depression and anxiety could be associated with their impaired physical exercise capability and reduced daily physical activity, according a new study published online by the Journal of Renal Nutrition.

29 May 2014

Study suggests that stiff arteries alone enough to cause high BP in "virtual human"

High blood pressure is highly age-related and affects more than 1 billion people worldwide. But doctors can't fully explain the cause of 90 per cent of all cases. A computer model of a "virtual human" suggests that stiff arteries alone are enough to cause high blood pressure.

27 May 2014

EKF affirms that novel sTNFR1/2 biomarkers can help predict end-stage renal disease

EKF, confirms scientific evidence as validation that soluble TNF Receptors 1 and 2 are strong biomarkers of progressive Diabetic Kidney Disease.

From EKF Diagnostics 23 May 2014

Kidney transplant recipients live longer than patients on intensive home hemodialysis

A first-ever study from a large Canadian centre found that kidney transplant recipients lived longer and had better treatment success than patients on intensive home hemodialysis, but also had an increased risk of being hospitalized within the first year.

23 May 2014

Walking shown to improve clinical outcomes in patients with kidney disease

A recent study indicates that walking can reduce the risks of premature death and the need for dialysis or kidney transplant among patients with kidney disease.

16 May 2014

Promedior to present interim data from PRM-151 Phase 2 trial at ASCO 2014 Annual Meeting

Promedior, Inc., a clinical stage biotechnology company developing novel therapeutics for the treatment of fibrosis, today announced that principal investigator, Srdan Verstovsek, MD, PhD, will present interim data from the Company's ongoing Phase 2 clinical trial of its lead product candidate, PRM-151, for the treatment of myelofibrosis, in a poster presentation on June 2, 2014 at the American Society for Clinical Oncology 2014 Annual Meeting.

15 May 2014

Fourteen businesses receive innovative funding to improve kidney care

NEW ideas and technologies that could prevent kidney disease, allow earlier diagnosis and give patients greater independence are to be developed thanks to an innovative funding competition developed.

From Randox Laboratories Ltd. 15 May 2014

Retrophin reports net loss of $70.6 million for first quarter 2014

Retrophin, Inc. today reported its financial results for the quarter ended March 31, 2014.

14 May 2014

Study reveals sea salt and table salt have equivalent sodium content

Pink Himalayan, Breton Gray and Hawaiian Alea - the newer offerings of salt may be exotic, cost more and frequent the shelves of high-end stores, but they are just as bad for you as common table salt.

14 May 2014

Akebia Therapeutics reports net loss of $9.7 million for Q1 2014

Akebia Therapeutics, Inc., a biopharmaceutical company focused on the development of novel, proprietary therapeutics based on hypoxia-inducible factor (HIF) biology and the commercialization of these products for patients with kidney disease, today announced financial results for the first quarter ended March 31, 2014.

12 May 2014

Study: Pravastatin slows down growth of kidney cysts in children, young adults with ADPKD

Results from a study by University of Colorado School of Medicine researchers show that pravastatin, a medicine widely used for treatment of high cholesterol, also slows down the growth of kidney cysts in children and young adults with autosomal dominant polycystic kidney disease (ADPKD).

9 May 2014

3 pioneering cell biologists win 2014 E.B. Wilson Medal from American Society for Cell Biology

If cells were cars, then the three pioneering cell biologists just named winners of the 2014 E.B. Wilson Medal, the highest scientific honor of the American Society for Cell Biology, helped write the essential parts list.

8 May 2014

Research may have "major implications" for treatment of urinary tract infections in children

A major new pediatric research study led by a Wayne State University researcher, funded by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health (NIH) and published this week in the New England Journal of Medicine (NEJM), has "major implications" for the treatment of urinary tract infections (UTIs) in millions of American children.

8 May 2014

Nephropathy News and Research

Further Reading

Thrasos presents positive results of THR-184 compound for treatment of acute kidney injury

Vitamin D with calcium can protect against risk of common bone fractures for seniors

Findings could lead to treatments for blood disorders associated with iron deficiencies and overloads

Promedior reports positive preliminary data from PRM-151 Phase 2 trial for myelofibrosis

Researchers create experimental blood test that determines BHI by gauging performance of mitochondria

Reduced glomerular filtration rate is independent risk factor for renal and urothelial cancer

People with diabetes have about double risk of premature death

Dialysis patients suffering from depression and anxiety have greatest impairments in physical exercise

Study suggests that stiff arteries alone enough to cause high BP in "virtual human"

EKF affirms that novel sTNFR1/2 biomarkers can help predict end-stage renal disease

Kidney transplant recipients live longer than patients on intensive home hemodialysis

Walking shown to improve clinical outcomes in patients with kidney disease

Promedior to present interim data from PRM-151 Phase 2 trial at ASCO 2014 Annual Meeting

Fourteen businesses receive innovative funding to improve kidney care

Retrophin reports net loss of $70.6 million for first quarter 2014

Study reveals sea salt and table salt have equivalent sodium content

Akebia Therapeutics reports net loss of $9.7 million for Q1 2014

Study: Pravastatin slows down growth of kidney cysts in children, young adults with ADPKD

3 pioneering cell biologists win 2014 E.B. Wilson Medal from American Society for Cell Biology

Research may have "major implications" for treatment of urinary tract infections in children

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