Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Researchers discussed studies that explored T-cell immunity induced by SARS-CoV-2 infection and COVID-19 vaccination in cancer patients, individuals with HIV, and recipients of solid organ transplants.

8 Feb 2023

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers analyzed data from the Increasing Community Access to Testing (ICATT), a nationwide pharmacy program run in the US for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.

7 Feb 2023

Mucoactive drugs block SARS-CoV-2 infection

Researchers evaluate the effects of mucociliary active molecules on SARS-CoV-2 infection in vitro.

7 Feb 2023

Study reports two cases of ocular MPox in HIV-infected patients

Researchers review the symptoms, diagnosis, and treatment of ocular Mpox syndrome in men living with HIV infection.

7 Feb 2023

Study highlights the emergence of S. cerevisiae as an opportunistic fungal pathogen in immunosuppressed patients presenting several severe comorbidities

Researchers from Brazil presented a fatal case of a patient developing Saccharomyces cerevisiae infection and succumbing to septic shock after contracting and recovering from a SARS-CoV-2 infection.

7 Feb 2023

A novel multiplexed assay to diagnose Mpox and other viruses

Researchers evaluate the performance of novel assay to identify Mpox viral infection.

6 Feb 2023

Detecting novel SARS-CoV-2 variants via rapid RT-PCR assays

A new study on the medRxiv* preprint server assessed whether a novel assay could detect VOCs without substantial reductions in sensitivity.

6 Feb 2023

Study suggests that both mother and infant can contribute to the human milk microbiome

Researchers examined associations between the bacterial composition of human milk and maternal and infant factors.

6 Feb 2023

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

Pfizer COVID-19 vaccine protects against reinfection in long-term care facility staff

Researchers examines the effectiveness of the Pfizer-BioNTech COVID-19 vaccine among long-term care facility staff members.

2 Feb 2023

Multispecies cluster of SARS-CoV-2 infections associated with an infected African lion

A recent paper described, for the first time, the transmission of this virus from an animal in a zoo to zoo employees.

2 Feb 2023

Establishment of a rapid and accurate SARS-CoV-2 antigen detection kit able to identify Omicron mutants

Researchers developed an antigen detection kit to identify the SARS-CoV-2 Omicron variant of concern.

2 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

The trajectory of long-COVID in the general population of Scotland

Researchers presented the findings of the Long-COVID in Scotland Study (Long-CISS) conducted nationwide among the general population of Scotland.

2 Feb 2023

Risk factors for Omicron reinfections among previously infected frontline workers in the United States

Researchers examined a prospective cohort of frontline workers in the United States (US) previously infected with SARS-CoV-2. They attempted to identify risk factors that made this highly vulnerable population prone to reinfection by SARS-CoV-2 new variant of concern (VOC), Omicron, known for its high immune evading potential.

1 Feb 2023

Polymerase Chain Reaction News and Research

Further Reading

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

Mucoactive drugs block SARS-CoV-2 infection

Study reports two cases of ocular MPox in HIV-infected patients

Study highlights the emergence of S. cerevisiae as an opportunistic fungal pathogen in immunosuppressed patients presenting several severe comorbidities

A novel multiplexed assay to diagnose Mpox and other viruses

Detecting novel SARS-CoV-2 variants via rapid RT-PCR assays

Study suggests that both mother and infant can contribute to the human milk microbiome

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Pfizer COVID-19 vaccine protects against reinfection in long-term care facility staff

Multispecies cluster of SARS-CoV-2 infections associated with an infected African lion

Establishment of a rapid and accurate SARS-CoV-2 antigen detection kit able to identify Omicron mutants

Researchers report a heterologous vaccination strategy against IBV in Chickens

The trajectory of long-COVID in the general population of Scotland

Risk factors for Omicron reinfections among previously infected frontline workers in the United States

Effectiveness of exome and genome sequencing to detect undiagnosed syndromes

COVID-19 might increase risk of autoimmune diseases

Study demonstrates intrahost MPXV variation within a single lesion

Acute tubulointerstitial nephritis and uveitis in children post-COVID-19

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo