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Researchers discover novel targeting agents to prevent cancer metastasis

Recently, a research team led by Maurizio Pellecchia at the University of California, Riverside, discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

26 Sep 2018

Mesoblast’s MPC therapy for children featured at symposium for congenital heart disease

Mesoblast Limited today announced that Mesoblast's proprietary allogeneic mesenchymal precursor cell heart failure product candidate MPC-150-IM for use in children with hypoplastic left heart syndrome was featured at the First Cardiac Regenerative Symposium for Congenital Heart Disease in Baltimore, Maryland on the weekend.

26 Sep 2018

Urine exRNA may be source of biomarkers for muscular dystrophy

Massachusetts General Hospital researchers have found that extracellular RNA in urine may be a source of biomarkers for the two most common forms of muscular dystrophy, noninvasively providing information about whether therapeutic drugs are having the desired effects on a molecular level.

26 Sep 2018

Exercise and diet may reduce obesogenic effects of PFAS

A new study finds that perfluoroalkyl and polyfluoroalkyl substances are associated with increases in weight, but exercise and diet may reduce the obesogenic effects of these environmental contaminants.

26 Sep 2018

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Sometimes negative results can point researchers in the right direction. In results published in PLOS ONE on September 4, 2018, scientists at the Medical University of South Carolina examined a protein called vaccinia-related kinase 1 that they hypothesized was important for metastasis. They found that, rather than causing cancer cells to migrate and invade, VRK1 over-expression had the opposite effect.

26 Sep 2018

Recurrence risk of VTE appears similar for patients with cancer and those with unprovoked VTE

Patients with venous thromboembolism carry a high risk of recurrence. Accordingly, a 16-year Danish prospective cohort study of nearly 74,000 patients with incident VTE concluded that the risk of recurrence is substantial.

25 Sep 2018

Lancaster professor aims to understand how genes affect smoking cessation

The Canadian Institute of Health Research has awarded $929,475 to Professor Jo Knight of Lancaster Medical School, Lancaster Data Science Institute and the Department of Psychiatry at the University of Toronto.

25 Sep 2018

Lung cancer patients treated with invasive surgery more likely to become chronic opioid users

Patients treated with more-invasive surgical techniques for a type of early-stage lung cancer are more likely to become chronic opioid users than patients treated with minimally invasive surgery, highlighting the need for additional research into how pain management after surgery might be a contributing factor to the opioid addiction crisis, according to a study published in JAMA Oncology in September.

24 Sep 2018

Researchers find impact of neurobehavioral symptoms on employment in adults with TBI

Kessler Foundation researchers have published their findings linking behavioral symptoms with employment outcomes among adults with moderate to severe traumatic brain injury.

24 Sep 2018

Vanteres announces new evidence demonstrating role of LPC-DHA in fetal brain development

Vanteres, an innovative biotech company leveraging its biomedical research expertise to develop actively transported lysophospholipids, announces new evidence that demonstrates the critical role of LPC-DHA in normal fetal and infant brain development.

24 Sep 2018

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

AstraZeneca today announced positive results from the Phase III DECLARE-TIMI 58 cardiovascular outcomes trial for FARXIGA, the broadest SGLT-2 inhibitor CVOT conducted to date.

24 Sep 2018

New study finds height as possible risk factor for developing varicose veins

The taller you are, the more likely you are to develop varicose veins, according to a study led by Stanford University School of Medicine researchers that examined the genes of more than 400,000 people in search of clues to what causes this common but little understood condition.

24 Sep 2018

Most patients who underwent transcatheter valve replacement experience prosthesis-patient mismatch

In the largest multi-institutional study to date, led by researchers from Penn Medicine, the team found that among patients who underwent a transcatheter aortic valve replacement, a high number experienced severe and moderate cases of prosthesis-patient mismatch--meaning the implanted heart valve is too small for the patient which can lead to inadequate blood flow.

24 Sep 2018

New therapeutic vaccine helps immune cells fight HPV-related head and neck cancer

A therapeutic vaccine can boost antibodies and T cells, helping them infiltrate tumors and fight off human papillomavirus-related head and neck cancer.

24 Sep 2018

New research suggests power of zebrafish as tool for cancer drug discovery

The lab of Leonard Zon, MD, at Boston Children's Hospital has long been interested in making blood stem cells in quantity for therapeutic purposes.

24 Sep 2018

Research scientist at Kessler Foundation receives $10,000 grant to study aphasia after stroke

Olga Boukrina, PhD, research scientist in Stroke Rehabilitation Research at Kessler Foundation, has received a $10,000 grant from the Mabel H. Flory Charitable Trust.

21 Sep 2018

Study offers solid link between visceral organs and brain’s reward, motivation system

A novel gut-to-brain neural circuit establishes the vagus nerve as an essential component of the brain system that regulates reward and motivation, according to research conducted at the Icahn School of Medicine at Mount Sinai and published September 20 in the journal Cell.

21 Sep 2018

Medical School News and Research

Researchers discover novel targeting agents to prevent cancer metastasis

Mesoblast’s MPC therapy for children featured at symposium for congenital heart disease

Urine exRNA may be source of biomarkers for muscular dystrophy

Exercise and diet may reduce obesogenic effects of PFAS

VRK1 protein may enable cancer cells to colonize new areas of the body during metastasis

Recurrence risk of VTE appears similar for patients with cancer and those with unprovoked VTE

Lancaster professor aims to understand how genes affect smoking cessation

Lung cancer patients treated with invasive surgery more likely to become chronic opioid users

Researchers find impact of neurobehavioral symptoms on employment in adults with TBI

Vanteres announces new evidence demonstrating role of LPC-DHA in fetal brain development

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

New study finds height as possible risk factor for developing varicose veins

Most patients who underwent transcatheter valve replacement experience prosthesis-patient mismatch

New therapeutic vaccine helps immune cells fight HPV-related head and neck cancer

New research suggests power of zebrafish as tool for cancer drug discovery

Research scientist at Kessler Foundation receives $10,000 grant to study aphasia after stroke

Study offers solid link between visceral organs and brain’s reward, motivation system

Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia

Cell Medica successfully doses first patient with CMD-501 targeting pediatric neuroblastoma

Scientists better understand influenza virus and how it spreads

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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