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Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

A phase III clinical trial conducted at the Meir Medical Center in Kfar-Saba, Israel is now recruiting participants to study the effects of dietary supplement PectaSol-C modified citrus pectin (MCP) in controlling prostate specific antigen (PSA) levels in prostate cancer patients.

15 Apr 2014

Researchers identify new Chinese herbal medicine that inhibits hepatitis C virus activity

Data from a late-breaking abstract presented at the International Liver CongressTM 2014 identifies a new compound, SBEL1, that has the ability to inhibit hepatitis C virus (HCV) activity in cells at several points in the virus' lifecycle.

15 Apr 2014

TSRI announces formation of Scripps Advance

The Scripps Research Institute (TSRI) today announced the formation of Scripps Advance, a new drug discovery initiative to translate early-stage biomedical research projects, both internal and external to TSRI, into clinical development candidates.

15 Apr 2014

New technique of single-cell genomic analysis to reverse tissue engineering

Consider the marvel of the embryo. It begins as a glob of identical cells that change shape and function as they multiply to become the cells of our lungs, muscles, nerves and all the other specialized tissues of the body.

15 Apr 2014

Researchers figure out role of birth weight and breastfeeding in long run health outcomes

Lower weight babies and babies who aren't breastfed or not breastfed for long are at greater risk of developing chronic inflammation and related health problems later in life, according to a new study.

15 Apr 2014

Domain Therapeutics receives grant to support development of mGluR3 PAM for Parkinson’s disease

Domain Therapeutics, a biopharmaceutical company specializing in the research and development of new drug candidates targeting G protein-coupled receptors (GPCRs), today announces the receipt of a second grant of 230 000 dollars (USD) from The Michael J. Fox Foundation for Parkinson’s Research to support its metabotropic glutamate receptor type III (mGluR3) positive allosteric modulators (PAM) program.

15 Apr 2014

Engineers develop tools to efficiently analyze living cells

For more than a decade Chang Lu, associate professor of chemical engineering at Virginia Tech, has worked on the development of tools to efficiently analyze living cells. The long-term goal is to gain a better understanding of a range of diseases.

15 Apr 2014

Researchers investigate role of microRNAs in breast cancer cells

Metastasis — the spreading of cancer cells from a primary tumor site to other parts of the body — generally leads to poorer outcomes for patients, so oncologists and researchers are constantly seeking new ways to detect and thwart this malicious process.

15 Apr 2014

Scientists discover how bacterium Y. pestis overwhelms lungs to cause pneumonic plague

Northwestern Medicine scientists are continuing to unravel the molecular changes that underlie one of the world's deadliest and most infamous respiratory infections.

15 Apr 2014

Scientists uncover mechanism and possible treatment to reverse immune suppression in liver disease patients

The mechanism which underlies the susceptibility of liver disease patients to life-threatening infection has been uncovered by Wellcome Trust-funded medical scientists, who have also suggested a possible treatment to reverse immune suppression in these patients.

15 Apr 2014

Two candidate mTOR therapy biomarkers identified in RCC

Two genes, TSC1 and MTOR, warrant further investigation as biomarkers for treatment benefit with rapalogs in patients with renal cell carcinoma, indicate study results published in Clinical Cancer Research.

14 Apr 2014

Researchers identify eight new active molecules against Alzheimer

Researchers of the Unit of Medicine Design and Molecular Topology (Department of Physics Chemistry) of the University of Valencia have discovered eight new active molecules against Alzheimer by a novel mechanism of action, different to the currently used medicines. The work has just been published in the "Plos One" magazine.

11 Apr 2014

Researchers uncover new aspect of autism

A team of researchers from the University of California, San Diego School of Medicine and the Center for Cancer Systems Biology at the Dana-Farber Cancer Institute has uncovered a new aspect of autism, revealing that proteins involved in autism interact with many more partners than previously known. These interactions had not been detected earlier because they involve alternatively spliced forms of autism genes found in the brain.

11 Apr 2014

Researchers discover tumor suppressor gene folliculin essential to normal lung function in BHD patients

Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, a genetic disorder that affects the lungs, skin and kidneys.

11 Apr 2014

Proteomics completes important milestone towards development of CDx test with validation of protein biomarkers

Proteomics now seeks a commercialisation partner to enter the RUO, LDT or IVD markets. Drug discovery company Proteomics International has completed an important milestone towards the development of a companion diagnostic (CDx) test with the validation of several of its protein biomarkers.

11 Apr 2014

Scientists discover protein potentially good target for influenza A virus

Scientists at The University of Texas at Austin have discovered that a protein produced by the influenza A virus helps it outwit one of our body's natural defense mechanisms. That makes the protein a potentially good target for antiviral drugs directed against the influenza A virus.

11 Apr 2014

Too much of c-FLIPR protein can trigger autoimmune diseases

So-called c-FLIP proteins inhibit signaling cascades that can lead to apoptosis. This is important temporarily in the response to pathogens to ensure that lymphocytes, a type of immune cells, can proliferate sufficiently.

11 Apr 2014

Researchers develop novel assay to identify genes controlling pharynx regeneration in flatworms

As multicellular creatures go, planaria worms are hardly glamorous. To say they appear rudimentary is more like it. These tiny aquatic flatworms that troll ponds and standing water resemble brown tubes equipped with just the basics: a pair of beady light-sensing "eyespots" on their head and a feeding tube called the pharynx (which doubles as the excretory tract) that protrudes from a belly sac to suck up food.

11 Apr 2014

New procedure helps curtail complication rate associated with bone grafting

UT Arlington and Texas Health Arlington Memorial Hospital are investigating whether bone grown from the body's own stem cells can replace traditional types of bone grafting.

11 Apr 2014

Scientists identify enzyme that could be a useful target in treating asthma, cancer

In experiments with mice, Johns Hopkins Kimmel Cancer Center scientists have identified an enzyme involved in the regulation of immune system T cells that could be a useful target in treating asthma and boosting the effects of certain cancer therapies.

11 Apr 2014

G Protein News and Research

Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

Researchers identify new Chinese herbal medicine that inhibits hepatitis C virus activity

TSRI announces formation of Scripps Advance

New technique of single-cell genomic analysis to reverse tissue engineering

Researchers figure out role of birth weight and breastfeeding in long run health outcomes

Domain Therapeutics receives grant to support development of mGluR3 PAM for Parkinson’s disease

Engineers develop tools to efficiently analyze living cells

Researchers investigate role of microRNAs in breast cancer cells

Scientists discover how bacterium Y. pestis overwhelms lungs to cause pneumonic plague

Scientists uncover mechanism and possible treatment to reverse immune suppression in liver disease patients

Two candidate mTOR therapy biomarkers identified in RCC

Researchers identify eight new active molecules against Alzheimer

Researchers uncover new aspect of autism

Researchers discover tumor suppressor gene folliculin essential to normal lung function in BHD patients

Proteomics completes important milestone towards development of CDx test with validation of protein biomarkers

Scientists discover protein potentially good target for influenza A virus

Too much of c-FLIPR protein can trigger autoimmune diseases

Researchers develop novel assay to identify genes controlling pharynx regeneration in flatworms

New procedure helps curtail complication rate associated with bone grafting

Scientists identify enzyme that could be a useful target in treating asthma, cancer

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