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Study reveals how apoE4 gene confers risk for Alzheimer's disease in brain cells

Using human brain cells, scientists at the Gladstone Institutes discovered the cause of--and a potential solution for--the primary genetic risk factor for Alzheimer's disease, a gene called apoE4.

9 Apr 2018

Researchers develop new animal model to study Crimean-Congo hemorrhagic fever

Crimean-Congo hemorrhagic fever is a viral disease spread by ticks in the Middle East, Asia, Africa and parts of Europe. Infection with CCHF virus is fatal in nearly one of every three cases.

9 Apr 2018

Using Cord Blood to Alleviate the Symptoms of Autism

Cord blood has been studied extensively for the treatment of hematological diseases such as cancer and sickle cell anemia, but is now in phase II trials for the alleviation of autism. Dr. Ann Smith, director of Smart Cells who provided the cord blood for the trial, discusses the research and it's potential.

9 Apr 2018

Novel biomarker helps optimize anticancer therapy

Researchers have identified a biomarker that can be used to visualize blood vessel activity and optimize the timing of anticancer therapy.

9 Apr 2018

Vascular stabilization biomarker helps optimize timing of anticancer therapies

Angiogenesis, the formation of new blood vessels, is essential for tumor growth. A new study reported in The American Journal of Pathology describes a vascular stabilization biomarker that can visualize blood vessel activity, thus optimizing the timing of anticancer therapies including anti-angiogenics.

9 Apr 2018

Using the Microbiome to Predict the Risk of Cirrhosis-Associated Hospitalization

The microbiome is the collection of microorganisms that colonize the human body. Dr. Jasmohan Bajaj discusses the relationship between the microorganisms in the gut and cirrhosis, and how microbiome analysis can be used to predict the risk of cirrhosis-associated hospitalizations.

7 Apr 2018

Unexpected finding may play major role in deterring diabetic retinopathy

Diabetic retinopathy is considered one of the most disabling complications of diabetes and the leading cause of new cases of vision loss among adults.

6 Apr 2018

New insights into faster bone healing and new biomaterials

Most of us don't think about our teeth and bones until one aches or breaks. A team of engineers at Washington University in St. Louis looked deep within collagen fibers to see how the body forms new bone and teeth, seeking insights into faster bone healing and new biomaterials.

6 Apr 2018

Study highlights maternity care concerns for pregnant women with Ehlers-Danlos syndromes

Maternity care for pregnant women with Ehlers-Danlos syndromes 'must improve', researchers say.

5 Apr 2018

Autofluorescence imaging evaluates cell metabolism and wound healing

Kyle Quinn, assistant professor of biomedical engineering at the University of Arkansas, has published a review highlighting recent advances in autofluorescence imaging and discussing its role in evaluating cell metabolism.

5 Apr 2018

New point-of-care test accelerates diagnosis of Lyme neuroborreliosis

A new research-based point-of-care test has been developed in Finland for detecting the Lyme neuroborreliosis spread by ticks.

5 Apr 2018

New analysis on skin cancer screening rates among indoor tanners

Skin cancer screening is underused by indoor tanners.

5 Apr 2018

Researchers create adult-like cardiac model by introducing early stimulation

Researchers are now able to use induced pluripotent stem cells to form a model of human adult-like cardiac muscle by introducing electric and mechanical stimulation at an early stage. Since this muscle is similar to the adult heart, it could serve as a better model for testing the effects of drugs and toxic substances than current tissue engineered heart models.

5 Apr 2018

Scientists develop new drug for treating skin lesions in rare intractable disease

Scientists at Osaka University developed a new drug treating skin lesions in tuberous sclerosis complex (TSC), a rare intractable disease, a world first.

5 Apr 2018

New discovery may offer insight into treating sickle cell anemia and other blood disorders

Discovery by Scripps Research scientists may offer insight into treating blood disorders such as sickle cell anemia.

4 Apr 2018

Photoswitchable drugs may light the way to treat disease with fewer side effects

Side effects from drugs working in non-target locations within the body can cause debilitating symptoms, often resulting in patients stopping their course of treatment early.

4 Apr 2018

MIT researchers develop new portable device to monitor white blood cell levels

One of the major side effects of chemotherapy is a sharp drop in white blood cells, which leaves patients vulnerable to dangerous infections. MIT researchers have now developed a portable device that could be used to monitor patients' white blood cell levels at home, without taking blood samples.

3 Apr 2018

Human genome is like a time machine, says researcher

The human genome is a bit like a time machine, says Ben Voight, an associate professor in Systems Pharmacology and Translational Therapeutics and of Genetics in Penn's Perelman School of Medicine.

3 Apr 2018

Lipodystrophy: The Importance of Awareness

An interview with Rebecca Sanders, Lipodystrophy UK co-founder, discussing the importance of awareness campaigns for patients and society at large.

3 Apr 2018

Study uncovers mechanism causing chronic GVHD after bone marrow transplant

Allogeneic bone marrow transplant (BMT) is an essential treatment to cure patients with blood cancers such as leukemia. In patients who have undergone chemotherapy and radiation, a small number of cancer cells can remain in the bloodstream and allow the malignancy to recur.

3 Apr 2018