Therapeutics News and Research

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Study shows improvements in adherence, outcomes of gout patients receiving text message reminders

The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate significant improvements in adherence and clinical outcomes in gout patients who received a daily text message to remind them to take allopurinol.

14 Jun 2018

Pharmacists can play key role in resolving treatment-related problems among undeserved people

Pharmacist-delivered home medication management review service effectively resolves treatment-related problems in patients displaced by humanitarian crisis, according to a new study published in Research in Social and Administrative Pharmacy

14 Jun 2018

Combining financial incentives and goal-setting with wearables may encourage heart patients to exercise

Combining financial incentives and personalized goal-setting with wearable devices may be an effective way of encouraging patients with heart disease to increase their physical activity.

13 Jun 2018

Novel approach induces cell death via dual targeting of DNA repair mechanism

Proteins commonly known as BRCA - short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development.

13 Jun 2018

AbCellera and Denali collaborate to discover new antibodies to fight neurodegenerative diseases

AbCellera Biologics Inc. today announced the successful completion of the first phase of its collaboration with Denali Therapeutics Inc.

12 Jun 2018

Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

Translate Bio, a clinical-stage messenger RNA therapeutics company developing a new class of potentially transformative medicines to treat diseases caused by protein or gene dysfunction, announced today a multi-year research and development collaboration and exclusive licensing agreement with Sanofi Pasteur, the vaccines global business unit of Sanofi, to develop mRNA vaccines for up to five undisclosed infectious disease pathogens.

11 Jun 2018

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today new positive results from its Phase 1/2 study with lumasiran, an investigational RNAi therapeutic targeting glycolate oxidase for the treatment of Primary Hyperoxaluria Type 1.

8 Jun 2018

PENTAX Medical launches new C2 CryoBalloon Ablation System for treatment of Barretts esophagus

PENTAX Medical Company, a healthcare industry leader in diagnostic and therapeutic endoscopy, announces the introduction of the C2 CryoBalloon Ablation System for the treatment of Barrett’s esophagus, a condition in which the lining of the esophagus develops abnormal lesions primarily as a result of chronic gastroesophageal reflux disease.

From PENTAX Medical Company 8 Jun 2018

Collaborative research team seeks to collapse a tiny pocket between cardiac cells

A collaborative research team is on a quest to collapse a tiny pocket between cardiac cells that can cause big problems. Called the perinexus, the structure spans only tenths of a millimeter -- all the space it needs to disrupt a person's heartbeat.

7 Jun 2018

Regeneron collaborates with Zoetis to research antibody therapies for animals

Regeneron Pharmaceuticals, Inc. and Zoetis Inc. today announced a five-year collaboration to research the use of Regeneron's monoclonal antibody therapeutics in animals and discover new veterinary treatments.

6 Jun 2018

Microbiotica collaborates with Genentech to develop drugs for IBD

Microbiotica, a leading player in microbiome-based therapeutics spun out of the Wellcome Sanger Institute, today announced that it has entered into a multi-year strategic collaboration with Genentech, a member of the Roche Group, to discover, develop and commercialize biomarkers, targets and medicines for inflammatory bowel disease.

6 Jun 2018

Scientists uncover new way to make cancers sensitive to treatment

Scientists have uncovered a completely new way to make cancers sensitive to treatment - by targeting antenna-like structures on cells.

6 Jun 2018

IONTAS collaborates with LG Chem to discover antibodies for treating cancer

IONTAS Limited, a leader in the discovery and optimisation of fully human antibodies, today announced it has signed a collaboration agreement with Korean-based LG Chem, Ltd. for the discovery of therapeutic antibodies targeting undisclosed targets for use in the treatment of cancers.

5 Jun 2018

Altering bacteria’s genetic code may pave way for long-lasting drugs, shows study

By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with cancer and other diseases.

5 Jun 2018

Scientists uncover 'Achilles heel' in deadly form of brain cancer

Scientists at Virginia Commonwealth University believe they have uncovered an "Achilles heel" of glioblastoma multiforme, the most common and deadly form of brain cancer.

5 Jun 2018

Researchers use 'multiomics' approach to study newborn mouse heart

During the first days of life, the heart of a newborn mouse adapts to entirely new physiological conditions, larger volume loads and an increased energy demand. As a result, fundamental changes occur in the heart. Studies have shown that the heart of neonate mouse retains its ability to effectively repair tissue damage.

4 Jun 2018

MiNA Therapeutics announces initial results from phase I trial of saRNA candidate in liver cancer patients

MiNA Therapeutics, the pioneer in RNA activation therapeutics, today announced preliminary results from its ongoing Phase I study of small activating RNA candidate MTL-CEBPA in advanced liver cancer.

4 Jun 2018

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the "stemness" of chronic leukemia cancer cells - their ability to self-renew and resist terminal differentiation and senescence.

1 Jun 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

Discovering Antibodies with Universal Specificity

Professor Hedda Wardemann discusses our current knowledge of antibody specificity and how her research team are challenging this, through the discovery of anti-bacterial antibodies with universal specificity.

1 Jun 2018

Therapeutics News and Research

Study shows improvements in adherence, outcomes of gout patients receiving text message reminders

Pharmacists can play key role in resolving treatment-related problems among undeserved people

Combining financial incentives and goal-setting with wearables may encourage heart patients to exercise

Novel approach induces cell death via dual targeting of DNA repair mechanism

AbCellera and Denali collaborate to discover new antibodies to fight neurodegenerative diseases

Translate Bio collaborates with Sanofi to develop mRNA vaccines for infectious diseases

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

PENTAX Medical launches new C2 CryoBalloon Ablation System for treatment of Barretts esophagus

Collaborative research team seeks to collapse a tiny pocket between cardiac cells

Regeneron collaborates with Zoetis to research antibody therapies for animals

Microbiotica collaborates with Genentech to develop drugs for IBD

Scientists uncover new way to make cancers sensitive to treatment

IONTAS collaborates with LG Chem to discover antibodies for treating cancer

Altering bacteria’s genetic code may pave way for long-lasting drugs, shows study

Scientists uncover 'Achilles heel' in deadly form of brain cancer

Researchers use 'multiomics' approach to study newborn mouse heart

MiNA Therapeutics announces initial results from phase I trial of saRNA candidate in liver cancer patients

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Discovering Antibodies with Universal Specificity

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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