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Study sheds light on how ‘junk DNA’ affects inherited cancer risk

A person’s risk of developing cancer is affected by genetic variations in regions of DNA that don’t code for proteins, previously dismissed as ‘junk DNA’, according to new research published in the British Journal of Cancer today (Friday).

6 Dec 2019

New approach can improve the activity of CAR-T cells against blood and solid cancers

A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in the laboratory and in mice, according to a study by researchers at the Stanford University School of Medicine.

5 Dec 2019

Young patients with IBD have increased risk of severe viral infections

Young patients with inflammatory bowel disease are five times more likely than the general population to develop viral infections that can lead to hospitalization or permanent organ damage, a new study published in the UEG Journal has found.

5 Dec 2019

Scientists identify how damaged DNA molecules are repaired inside the human genome

A team of scientists has identified how damaged DNA molecules are repaired inside the human genome, a discovery that offers new insights into how the body works to ensure its health and how it responds to diseases that stem from impaired DNA.

5 Dec 2019

DNA testing for siblings of children with ASD may be predictive of future diagnosis

One of the key priorities of interventions for autism spectrum disorder (ASD) is starting early, with some evidence showing infants as young as seven months old could benefit.

5 Dec 2019

New discovery on chromosomal function may shed light on human health and disease

Researchers have discovered key mechanisms and structural details of a fundamental biological process - how a cell nucleus and its chromosomal material reorganizes itself after cell division

5 Dec 2019

Experts condemn CRISPR babies research as original manuscript is made public

Scientists have criticized the gene-editing of the Chinese twins last year, following the first public release of the research.

4 Dec 2019

Study identifies improved treatment option for neuroblastoma

Neuroblastoma is a rare form of malignant tumor, primarily affecting children under the age of six. A research team led by molecular pathologist Lukas Kenner from MedUni Vienna's Department of Pathology has now discovered, through genome sequencing, that the protein ALK and the cancer gene PIM1 are involved in the development of this tumor.

4 Dec 2019

Researchers create new technology to help understand how the body battles diseases

Much remains unknown about diseases and the way our bodies respond to them, in part because the human genome is the complete DNA assembly that makes each person unique. A Virginia Tech professor and his team of researchers have created new technology to help in understanding how the human body battles diseases.

3 Dec 2019

Common cold virus could infect fetus via placenta

According to researchers, the common cold viruses are capable of infecting human placental cells and may thus transmit the infection to the fetus in the womb during pregnancy. The new study was published in the journal PLOS ONE, and provides the first concrete proof that this type of carriage is possible.

3 Dec 2019

Using genomics to identify promising novel treatment for lymphatic filariasis

Using innovative RNA sequencing techniques, researchers at the University of Maryland School of Medicine Institute for Genome Sciences identified a promising novel treatment for lymphatic filariasis, a disabling parasitic disease that is difficult to treat.

3 Dec 2019

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Along with the promise that CRISPR-Cas9 gene editing technology can offer new human therapies is the need to ensure its safety. A recent study showed that CRISPR-Cas9 did not produce off-target gene mutations in zebrafish. These results, published in Frontiers in Genetics, confirm previous data in animal models that the risk to the rest of the genome from gene editing is minimal.

3 Dec 2019

Discovery could offer insight into different risk of diseases in African Americans

The percentage of African ancestry in a person's genome determines the level that certain genes are expressed, called mRNA, according to a new Northwestern Medicine study.

3 Dec 2019

New model for late-onset sepsis explores potential treatments for neonatal infection

Extremely premature infants are at risk for life-threatening infections that spread into their bodies from the intestine. Infections after the first three days of life are called late-onset sepsis, or LOS.

3 Dec 2019

Researchers identify key protein required for therapeutic resistance in aggressive breast cancer

Researchers at the Lady Davis Institute have identified a key protein that is required for resistance to chemotherapy in the most aggressive form of breast cancer. This holds the promise of opening the door to new therapies for overcoming drug resistance.

2 Dec 2019

Blood proteins could help provide a comprehensive 'liquid health check' in future

Proteins in our blood could in future help provide a comprehensive 'liquid health check', assessing our health and predicting the likelihood that we will we will develop a range of diseases, according to research published today in Nature Medicine.

2 Dec 2019

75-year old blood-stained microscope slide reveals historical spread of malaria

DNA from 75-year old eradicated European malaria parasites uncovers the historical spread of one of the two most common forms of the disease, Plasmodium vivax, from Europe to the Americas during the colonial period, finds a new study co-led by UCL.

2 Dec 2019

Link found between the gut microbiome, host genome, and RA in Japanese population

One of the most astounding discoveries of recent times is just how much influence gut bacteria have on our health and well-being.

2 Dec 2019

“Liquid health check” could predict disease risk in the future

Measuring proteins in the blood could serve as a “liquid health check” that could predict people’s risk of developing diseases.

2 Dec 2019

Gene discovery in fruit flies could provide clues to counteract mitochondrial diseases

Scientists have identified a protein in fruit flies that can be targeted to reverse the effects of disease-causing mutations in mitochondrial genes. The discovery could provide clues about how to counteract human mitochondrial diseases, for which there is currently no cure.

28 Nov 2019

Genome News and Research

Study sheds light on how ‘junk DNA’ affects inherited cancer risk

New approach can improve the activity of CAR-T cells against blood and solid cancers

Young patients with IBD have increased risk of severe viral infections

Scientists identify how damaged DNA molecules are repaired inside the human genome

DNA testing for siblings of children with ASD may be predictive of future diagnosis

New discovery on chromosomal function may shed light on human health and disease

Experts condemn CRISPR babies research as original manuscript is made public

Study identifies improved treatment option for neuroblastoma

Researchers create new technology to help understand how the body battles diseases

Common cold virus could infect fetus via placenta

Using genomics to identify promising novel treatment for lymphatic filariasis

Zebrafish study supports accuracy of CRISPR-Cas9 gene editing tool

Discovery could offer insight into different risk of diseases in African Americans

New model for late-onset sepsis explores potential treatments for neonatal infection

Researchers identify key protein required for therapeutic resistance in aggressive breast cancer

Blood proteins could help provide a comprehensive 'liquid health check' in future

75-year old blood-stained microscope slide reveals historical spread of malaria

Link found between the gut microbiome, host genome, and RA in Japanese population

“Liquid health check” could predict disease risk in the future

Gene discovery in fruit flies could provide clues to counteract mitochondrial diseases

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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