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Scientists question CRISPR human embryo editing claims

A paper published in the journal Nature on the 2nd August described how a gene editing tool CRISPR could be used to correct a genetic mutation that leads to a heart condition. This team had performed the genetic editing on the gene sequences in dozens of viable human embryos to attempt to prevent a genetic heart condition called hypertrophic cardiomyopathy.

31 Aug 2017

Study identifies unexpected mosaic mutations as new risk factor for developing autism

Autism spectrum disorder affects approximately one out of every 68 children in the United States. Despite expansive study, the origin and risk factors of the complex condition are not fully understood.

31 Aug 2017

Study explores periodontal status of patients with Chédiak-Higashi syndrome

The International and American Associations for Dental Research have published an article titled "Periodontitis in Chédiak-Higashi Syndrome: An Altered Immunoinflammatory Response" in the JDR Clinical & Translational Research.

31 Aug 2017

St. Jude creates world’s largest collection of pediatric solid tumor samples

In an effort to improve outcomes for patients with some of the deadliest childhood cancers, St. Jude Children's Research Hospital scientists have created the world's largest collection of pediatric solid tumor samples, drug-sensitivity data and related information and have made the resource available at no charge to the global scientific community.

31 Aug 2017

Researchers decipher how some Listeria strains survive high food hygiene standards

Listeria monocytogenes is a foodborne pathogen that colonizes and reproduces on diverse food products including cheese or meat.

30 Aug 2017

Scientists aim is to better understand effects of DNA damage on aging process

The heredity substance DNA is the blueprint of our life. Like an instruction manual it contains all the information needed for cells and the body to function properly.

30 Aug 2017

Human ancestors responsible for transmitting ancient strains of herpesvirus, study finds

An international study of integrated HHV-6 has discovered that a small number of human ancestors, one from about 24,000 years ago, have been responsible for transmitting ancient strains of the virus to individuals today - affecting about a million people in the UK alone.

30 Aug 2017

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Scientists have discovered a network of genes and genetic regulatory elements in the lining of the intestines that has stayed remarkably the same from fishes to humans. Many of these genes are linked to human illnesses, such as inflammatory bowel diseases, diabetes and obesity.

30 Aug 2017

Scientists identify novel role for retrotransposons in shaping embryonic chromatin landscape

Retrotransposons are repetitive elements that form almost half of the mammalian genome. Even though they are so common, they have previously been considered to be fairly insignificant.

30 Aug 2017

Clinical benefit of LDL cholesterol lowering therapies could depend on reduction in apoB particles

The benefit of lowering low-density lipoprotein (LDL) cholesterol depends on how it is lowered, according to late-breaking results from a naturally randomised genetic trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in JAMA.

29 Aug 2017

Research findings potentially open door to new treatments for eye trauma and retinal disease

Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye's circuitry, new research shows. The findings potentially open the door to new treatments for eye trauma and retinal disease.

28 Aug 2017

Junk genes could one day offer framework for treating people with familial hypercholesterolemia

Scientists from UCLA and the Howard Hughes Medical Institute successfully used a gene that suppresses cholesterol levels as part of a treatment to reduce plaque in mice with a disorder called familial hypercholesterolemia.

26 Aug 2017

Collaborative project reaches milestone halfway point in constructing Kinase Chemogenomic Set

The Structural Genomics Consortium at the University of North Carolina at Chapel Hill (SGC-UNC), in partnership with the DiscoverX Corporation, has reached the milestone halfway point in its development of the Kinase Chemogenomic Set, a potent group of inhibitors which allow deeper exploration of the human kinome, a family of enzymes critical to understanding human disease and developing new therapies.

26 Aug 2017

Distinguishing biothreat look-alikes could aid biological surveillance

Biological "detectives" are tracking down biothreats such as the bacteria that causes tularemia ("rabbit fever"), but they constantly face the challenge of avoiding false positives.

26 Aug 2017

Pan-European initiative receives €3.7 million funding to train next generation of brain tumor researchers

A pan-European initiative led by the University of Plymouth designed to train the next generation of brain tumor researchers, has received funding of almost €3.7 million from the European Commission's Horizon 2020 - Research and Innovation Framework Program.

26 Aug 2017

Genome News and Research

Scientists question CRISPR human embryo editing claims

Study identifies unexpected mosaic mutations as new risk factor for developing autism

Study explores periodontal status of patients with Chédiak-Higashi syndrome

St. Jude creates world’s largest collection of pediatric solid tumor samples

Researchers decipher how some Listeria strains survive high food hygiene standards

Scientists aim is to better understand effects of DNA damage on aging process

Human ancestors responsible for transmitting ancient strains of herpesvirus, study finds

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Scientists identify novel role for retrotransposons in shaping embryonic chromatin landscape

Clinical benefit of LDL cholesterol lowering therapies could depend on reduction in apoB particles

Research findings potentially open door to new treatments for eye trauma and retinal disease

Junk genes could one day offer framework for treating people with familial hypercholesterolemia

Collaborative project reaches milestone halfway point in constructing Kinase Chemogenomic Set

Distinguishing biothreat look-alikes could aid biological surveillance

Pan-European initiative receives €3.7 million funding to train next generation of brain tumor researchers

Scientists develop new system to identify and characterize regulatory DNA sequences

Long non-coding RNAs could represent novel male infertility drug targets

Researchers aim to develop dynamic therapeutics for combating antiviral drug resistance

Variations in ancient mitochondrial DNA may play key role in predisposition to ASD

New international research project identifies subtypes of ocular melanoma

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