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Study: Response to combination immunotherapy in melanoma depends on proportion of immune cells

Whether a melanoma patient will better respond to a single immunotherapy drug or two in combination depends on the abundance of certain white blood cells within their tumors, according to a new study conducted by UC San Francisco researchers joined by physicians from UCSF Health.

20 Jul 2017

Study finds no convincing evidence to support link between PPI use and dementia risk

Several studies have reported associations between proton-pump inhibitor (PPI) use and dementia. New research published on July 18 in Gastroenterology, the official journal of the American Gastroenterological Association, puts these claims to rest.

20 Jul 2017

IBS scientists create first nanoparticle-based tissue adhesive to seal bleeding and guide surgery

As open surgery has gradually been replaced by minimally-invasive and image-guided procedures, tissue adhesives are taking the place of sutures and surgical staples.

19 Jul 2017

FDA approves fixed-dose combination tablet for treating adults with chronic hepatitis C

The U.S. Food and Drug Administration today approved Vosevi to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 without cirrhosis (liver disease) or with mild cirrhosis.

18 Jul 2017

Research shows how dietary essential fatty acids can help treat Alzheimer’s, other diseases

Understanding how dietary essential fatty acids work may lead to effective treatments for diseases and conditions such as stroke, Alzheimer's disease, age-related macular degeneration, Parkinson's disease and other retinal and neurodegenerative diseases.

18 Jul 2017

Study provides insights into intergenerational inheritance of epigenetic information

We are more than the sum of our genes. Epigenetic mechanisms modulated by environmental cues such as diet, disease or our lifestyle take a major role in regulating the DNA by switching genes on and off.

18 Jul 2017

FDA approves first extended adjuvant therapy to lower risk of breast cancer recurrence

The U.S. Food and Drug Administration today approved Nerlynx (neratinib) for the extended adjuvant treatment of early-stage, HER2-positive breast cancer.

18 Jul 2017

NIH researchers show how investigational drug works against rare, fatal genetic disease

Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1).

17 Jul 2017

VoxelCloud raises $8M for expanding scope of AI-based medical image analysis services

VoxelCloud, a startup focusing on medical artificial intelligence, has raised $8M in series A financing led by Sequoia Capital. The startup utilizes artificial intelligence and cloud-computing technologies to provide automated medical image analysis and clinical decision support for medical practitioners.

17 Jul 2017

Scientists reveal key role of excess gut calcium in C. diff infections

It lurks in hospitals and nursing homes, surviving the cleaning crew's attempt to kill it by holing up in a tiny hard shell. It preys upon patients already weak from disease or advanced age.

13 Jul 2017

Beaumont Health's new Proton Therapy Center starts treating cancer patients

Bill Baker, an 86-year-old Mid-Michigan man with brain cancer, is the first patient to receive treatment at Beaumont Health's new Proton Therapy Center at Beaumont Hospital in Royal Oak, Michigan.

13 Jul 2017

Ground-breaking new breast cancer drugs have manageable toxicity profile for most patients

A ground-breaking new class of oral drugs for treating breast cancer, known as cyclin-dependent kinase (CDK) inhibitors, are generally well-tolerated, with a manageable toxicity profile for most patients.

13 Jul 2017

Senators grill top Indian health officials about Trump budget

Leaders of the Indian Health Service struggled Wednesday at a Senate hearing to defend the Trump administration's plans to slash funding to the agency, which is reeling from quality of care problems at several of its hospitals, a doctor shortage and facilities showing their age.

13 Jul 2017

Targeting acid metabolite reduces size and spread of breast cancer

It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability to spread to the lungs.

12 Jul 2017

Computational analysis of open-access data points to new ways of using drugs

A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been approved for other uses.

12 Jul 2017

Scientists develop first app and method to predict heart events after liver transplant

The first app and score to determine the one-year risk of a liver transplant patient dying or being hospitalized for a heart attack or other cardiovascular complication has been developed by Northwestern Medicine scientists.

12 Jul 2017

Gelesis reports completion of treatment for last patient in pivotal GLOW study

Gelesis, Inc., a biotechnology company developing a novel category of therapies to safely induce weight loss, improve glycemic control, and treat other chronic diseases related to the gastrointestinal (GI) pathway, is pleased to report today that the last patient has completed treatment in the pivotal GLOW (Gelesis Loss Of Weight) Study.

12 Jul 2017

New study links hepatic inflammation to western diet

A new study in The American Journal of Pathology reports that mice fed a Western diet, which is high in fat and sugar, resulted in hepatic inflammation, especially in males. Moreover, liver inflammation was most pronounced in Western diet-fed male mice that also lacked farnesoid x receptor (FXR), a bile acid receptor.

12 Jul 2017

Contaminated blood scandal that infected thousands in 70’s and 80’s being investigated

In the 1970’s and 80’s thousands of people were infected with hepatitis C and HIV due to transfusion of contaminated blood that contained these viruses. A spokesperson for Theresa May, James Slack, today said that she, her health secretary Jeremy Hunt and the MPs sat together to announce a full review and inquiry into this disaster.

12 Jul 2017

Study reveals link between coffee and low mortality

A study published in the July 11 issue of the Annals of Internal Medicine suggests that people who drink coffee appear to have a longer life-span.

11 Jul 2017

Liver News and Research

Study: Response to combination immunotherapy in melanoma depends on proportion of immune cells

Study finds no convincing evidence to support link between PPI use and dementia risk

IBS scientists create first nanoparticle-based tissue adhesive to seal bleeding and guide surgery

FDA approves fixed-dose combination tablet for treating adults with chronic hepatitis C

Research shows how dietary essential fatty acids can help treat Alzheimer’s, other diseases

Study provides insights into intergenerational inheritance of epigenetic information

FDA approves first extended adjuvant therapy to lower risk of breast cancer recurrence

NIH researchers show how investigational drug works against rare, fatal genetic disease

VoxelCloud raises $8M for expanding scope of AI-based medical image analysis services

Scientists reveal key role of excess gut calcium in C. diff infections

Beaumont Health's new Proton Therapy Center starts treating cancer patients

Ground-breaking new breast cancer drugs have manageable toxicity profile for most patients

Senators grill top Indian health officials about Trump budget

Targeting acid metabolite reduces size and spread of breast cancer

Computational analysis of open-access data points to new ways of using drugs

Scientists develop first app and method to predict heart events after liver transplant

Gelesis reports completion of treatment for last patient in pivotal GLOW study

New study links hepatic inflammation to western diet

Contaminated blood scandal that infected thousands in 70’s and 80’s being investigated

Study reveals link between coffee and low mortality

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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