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Imatinib mesylate effectively treats children with neurofibromatosis type 1 tumors

Physician-researchers at Indiana University School of Medicine have reported the first effective therapy for a class of previously untreatable and potentially life-threatening tumors often found in children.

2 Nov 2012

XJB-5-131 compound suppresses symptoms of Huntington's in mice

There's new hope in the fight against Huntington's disease. A group of researchers that includes scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in mice.

2 Nov 2012

Study identifies monoacylglycerol lipase as new therapeutic target to treat Alzheimer's

Research led by Chu Chen, PhD, Associate Professor of Neuroscience at LSU Health Sciences Center New Orleans, has identified an enzyme called Monoacylglycerol lipase (MAGL) as a new therapeutic target to treat or prevent Alzheimer's disease.

2 Nov 2012

Multiple sclerosis disease activity reduced by leukaemia drug, even when first-line treatment has failed

A drug which was originally developed to treat leukaemia and other cancers of the immune system offers substantial improvements over existing treatments in reducing relapse rates for people with multiple sclerosis (MS), even when they have not responded well to first-line treatment, according to the results of two phase 3 trials published Online First in The Lancet.

1 Nov 2012

Blocking hyaluronidase activity can help repair brain damage associated with MS

Researchers at Oregon Health & Science University have discovered that blocking a certain enzyme in the brain can help repair the brain damage associated with multiple sclerosis and a range of other neurological disorders.

1 Nov 2012

Ischemic stroke: an interview with Dr Gregory Ford

A stroke is a sudden interruption of blood flow to the brain which deprives the brain of oxygen and nutrients. Approximately two millions brain cells die each minute during a stroke. This can lead to brain damage, physical and mental disability and death.

1 Nov 2012

Vitamin D and multiple sclerosis: an interview with Ellen Mowry

Vitamin D is actually a hormone. For the most part, humans obtain vitamin D through sun exposure. Ultraviolet light from the sun promotes the conversion of a compound in the skin to pre-vitamin D.

31 Oct 2012

Nabilone shows promise in treating diabetic neuropathy

A study from the University of Calgary's Hotchkiss Brain Institute shows there is evidence to support a new drug therapy called nabilone to treat diabetic neuropathy, or nerve pain.

31 Oct 2012

Salivary gland surgery in Germany ‘more common than expected’

Results from a German population-based study suggest that the incidence of surgically treated benign salivary gland diseases is higher than previously thought.

30 Oct 2012

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow nerve damage in patients with neurodegenerative diseases.

30 Oct 2012

New prostate cancer therapy triggers questions about cost, effectiveness and safety

Because proton therapy can be targeted much more precisely, it should minimize any damage to sensitive nerves and tissue around the prostate.

29 Oct 2012

Neuros Medical honored as most promising startup

Neuros Medical, Inc., a medical device company, was presented the 2012 Gold Electrode Award for Most Promising Startup at the Neurotech Leaders Forum conference in San Francisco. The award is given by Neurotech Reports, and highlights a company in the neuromodulation industry that holds the most promise.

29 Oct 2012

Musculoskeletal ultrasound being increasingly used for diagnosis and management of rheumatic diseases

More rheumatologists are embracing musculoskeletal ultrasound (MSUS) to diagnose and manage rheumatic diseases. In response, the American College of Rheumatology (ACR) assembled a task force to investigate and determine best practices for use of MSUS in rheumatology practice. The resulting scenario-based recommendations, which aim to help clinicians understand when it is reasonable to integrate MSUS into their rheumatology practices, now appear online in Arthritis Care & Research.

29 Oct 2012

Light-sensitive protein to study Parkinson's disease

Introducing a light-sensitive protein in transgenic nerve cells... transplanting nerve cells into the brains of laboratory animals... inserting an optic fibre in the brain and using it to light up the nerve cells and stimulate them into releasing more dopamine to combat Parkinson's disease...

29 Oct 2012

First Edition: October 29, 2012

Today's headlines include reports about how the presidential election's outcome could impact the insurance industry as well as the fate of people who are sick or uninsured.

29 Oct 2012

Neuraxial anesthesia should be promoted for bilateral total knee replacements: HSS

Using regional anesthesia rather than general anesthesia reduces the need for blood transfusions in patients undergoing bilateral total knee replacement, according to a new study by researchers at Hospital for Special Surgery, in New York City.

29 Oct 2012

Researchers use baker's yeast to identify new therapies for Lou Gehrig's disease

Amyotrophic lateral sclerosis, also called Lou Gehrig's disease, is a devastatingly cruel neurodegenerative disorder that robs sufferers of the ability to move, speak and, finally, breathe.

29 Oct 2012

Mouse model may provide clues on mechanism that links diabetes and aging to Alzheimer's

Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. In a new study published in Aging Cell, researchers at the Salk Institute for Biological Studies show, for the first time, that diabetes enhances the development of aging features that may underlie early pathological events in Alzheimer's.

29 Oct 2012

Study describes how Dbr1 gene halts toxic buildup of TDP-43-a protein

Scientists at the Gladstone Institutes and the Stanford University School of Medicine have discovered how modifying a gene halts the toxic buildup of a protein found in nerve cells. These findings point to a potential new tactic for treating a variety of neurodegenerative conditions, including amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease)-a fatal disease for which there is no cure.

29 Oct 2012

NewYork-Presbyterian/Columbia participates in Symplicity system trial for hypertension

Patients with hypertension whose blood pressure cannot be brought down to safe levels despite taking three or more medications may have some relief coming their way. An innovative, first-of-its-kind clinical trial for a device representing a dramatic shift in treatment approaches for the toughest-to-treat patients is currently being conducted at NewYork-Presbyterian Hospital.

From Medtronic 26 Oct 2012

Nerve News and Research

Imatinib mesylate effectively treats children with neurofibromatosis type 1 tumors

XJB-5-131 compound suppresses symptoms of Huntington's in mice

Study identifies monoacylglycerol lipase as new therapeutic target to treat Alzheimer's

Multiple sclerosis disease activity reduced by leukaemia drug, even when first-line treatment has failed

Blocking hyaluronidase activity can help repair brain damage associated with MS

Ischemic stroke: an interview with Dr Gregory Ford

Vitamin D and multiple sclerosis: an interview with Ellen Mowry

Nabilone shows promise in treating diabetic neuropathy

Salivary gland surgery in Germany ‘more common than expected’

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

New prostate cancer therapy triggers questions about cost, effectiveness and safety

Neuros Medical honored as most promising startup

Musculoskeletal ultrasound being increasingly used for diagnosis and management of rheumatic diseases

Light-sensitive protein to study Parkinson's disease

First Edition: October 29, 2012

Neuraxial anesthesia should be promoted for bilateral total knee replacements: HSS

Researchers use baker's yeast to identify new therapies for Lou Gehrig's disease

Mouse model may provide clues on mechanism that links diabetes and aging to Alzheimer's

Study describes how Dbr1 gene halts toxic buildup of TDP-43-a protein

NewYork-Presbyterian/Columbia participates in Symplicity system trial for hypertension

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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