Therapeutics News and Research

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Combination of probiotics and herbal supplement may prolong lifespan, research shows

You are what you eat. Or so the saying goes. Science now tells us that we are what the bacteria living in our intestinal tract eat and this could have an influence on how well we age.

1 Jun 2018

Study: Cellular housekeeping can help mammals live longer and healthier

Building on two decades of research, investigators at UT Southwestern have determined that "cellular housekeeping" can extend the lifespan and healthspan of mammals.

31 May 2018

Mesoblast and Cartherics form partnership to develop 'off-the-shelf' CAR-T therapies for solid cancers

Mesoblast Limited today announced that it has entered into a partnership with Cartherics Pty Ltd to develop allogeneic ‘off-the-shelf’ CAR-T cells armed with multiple targeting receptors for use in solid cancers. Off the shelf CAR-T therapies have the potential to reduce costs dramatically and open up this very effective treatment to millions of cancer patients across the world.

31 May 2018

NUS researchers find novel pathway to regulate blood pressure

New and better ways to fight hypertension and low blood pressure may be in the offing, thanks to the National University of Singapore scientists' discovery of how our blood pressure is controlled.

30 May 2018

NIH summit presents recommendations to accelerate treatment development for Alzheimer's disease

Experts from government, academia, industry, non-profit organizations put forward recommendations that provide a roadmap for an integrated, multidisciplinary research agenda necessary to inform priorities for Alzheimer's disease and related dementias.

26 May 2018

Exercise alters brain's dopamine system to help treat addiction, study finds

New research by the University at Buffalo Research Institute on Addictions has identified a key mechanism in how aerobic exercise can help impact the brain in ways that may support treatment - and even prevention strategies - for addiction.

25 May 2018

Antioxidant-enriched multivitamin may decrease respiratory illnesses in CF patients, finds study

Researchers at Children's Hospital Colorado and the University of Colorado School of Medicine have found that taking a specially formulated antioxidant-enriched multivitamin may decrease respiratory illnesses in people with cystic fibrosis.

24 May 2018

USC researchers develop new portable device for early-stage malaria detection

According to the World Health Organization, over 216 million people were infected with malaria in 2016, and 445,000 individuals died from the disease. The key to solving this health crisis is early-stage diagnosis when malaria therapeutics are most effective. A new prototype for a portable instrument capable early-stage malaria detection has been developed by a team of researchers at the USC Viterbi School of Engineering.

23 May 2018

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Scientists have just discovered that a small region of a cellular protein that helps long-term memories form also drives the neurodegeneration seen in Amyotrophic Lateral Sclerosis (ALS). This small part of the Ataxin-2 protein thus works for good and for bad.

23 May 2018

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Innate fear is an essential emotion for animals to avoid danger in a severe natural environment. Rodents kept in a laboratory also show instinctive fear behavior against the smell of predators such as foxes, cats or snakes despite having never seen them.

22 May 2018

Analysis of lymph node dissection shows no overall survival benefit in renal carcinoma patients

An analysis of lymph node dissection in renal cell carcinoma that has not spread to other organs indicates the procedure is often performed for stage 1 disease and shows no overall survival benefit.

21 May 2018

Clinical trial begins enrollment to test safety of experimental MERS treatments

Enrollment has begun in an early-stage clinical trial testing the safety of two human monoclonal antibodies (mAbs) designed to treat people infected with Middle East respiratory syndrome coronavirus (MERS-CoV).

18 May 2018

HSS study aims to find if bariatric surgery prior to knee replacement can improve outcomes

Could weight loss surgery before knee replacement improve outcomes or even eliminate the need for joint replacement in severely overweight patients? A study by researchers at Hospital for Special Surgery aims to answer that question.

18 May 2018

Rutgers Cancer Institute nurses research various topics to enhance patient experience

From peer and patient education to addressing treatment side effects and other patient care needs, nurses at Rutgers Cancer Institute of New Jersey researched a number of topics with an aim of enhancing the patient experience.

18 May 2018

Chemist begins new project to develop carbohydrate mimics to assist cancer therapies

Dr. Robert Britton firmly believes every molecule is important. This chemist doesn't want any molecule sitting unused on a laboratory shelf or in a fridge.

18 May 2018

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

Alexo Therapeutics, a clinical-stage immuno-oncology company developing therapies to block the CD47 checkpoint mechanism, today announced it has initiated ALX148 combination dosing with targeted antibody therapies in its Phase 1 clinical program in patients with advanced solid tumors and lymphoma.

17 May 2018

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Obsidian Therapeutics, Inc., a biotechnology company dedicated to the development of next-generation cell and gene therapies with pharmacologic operating systems, today announced that the company presented preclinical data on its regulated IL12 and IL15 programs at the Annual Meeting of the American Society of Gene and Cell Therapy in Chicago, IL.

17 May 2018

New insights regarding challenges in rare disease diagnosis, drug approval, and patient access

Value in Health, the official journal of ISPOR, announced today the publication of a series of articles offering important insight regarding the challenges in rare disease diagnosis, drug approval, and patient access.

17 May 2018

FDA allows KU Medical Center to begin clinical trial of novel cellular therapy for HR/SR aGvHD

The University of Kansas Medical Center announced that the U.S. Food and Drug Administration has cleared it to begin a first-in-human clinical trial of MSCTC-0010 in patients with de novo high-risk acute or steroid-refractory acute graft-versus-host disease (HR/SR aGvHD).

16 May 2018

Tufts University, BioLabs announce the opening of new biotech facility for life sciences entrepreneurs

Tufts University and BioLabs today announced the opening of Tufts Launchpad | BioLabs, a full-service biotech facility supporting high-potential, early-stage life sciences startup ventures in the Boston area.

16 May 2018

Therapeutics News and Research

Combination of probiotics and herbal supplement may prolong lifespan, research shows

Study: Cellular housekeeping can help mammals live longer and healthier

Mesoblast and Cartherics form partnership to develop 'off-the-shelf' CAR-T therapies for solid cancers

NUS researchers find novel pathway to regulate blood pressure

NIH summit presents recommendations to accelerate treatment development for Alzheimer's disease

Exercise alters brain's dopamine system to help treat addiction, study finds

Antioxidant-enriched multivitamin may decrease respiratory illnesses in CF patients, finds study

USC researchers develop new portable device for early-stage malaria detection

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Analysis of lymph node dissection shows no overall survival benefit in renal carcinoma patients

Clinical trial begins enrollment to test safety of experimental MERS treatments

HSS study aims to find if bariatric surgery prior to knee replacement can improve outcomes

Rutgers Cancer Institute nurses research various topics to enhance patient experience

Chemist begins new project to develop carbohydrate mimics to assist cancer therapies

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

New insights regarding challenges in rare disease diagnosis, drug approval, and patient access

FDA allows KU Medical Center to begin clinical trial of novel cellular therapy for HR/SR aGvHD

Tufts University, BioLabs announce the opening of new biotech facility for life sciences entrepreneurs

Advancing therapeutic biopolymer development eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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