Therapeutics News and Research

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Opioid pharmaceutical marketing influences physicians' opioid prescribing rates

A new study shows the significant impact that even a meal or two paid for by a pharmaceutical company can have on prescribing rates, despite a national decline of opioid prescribing rates.

15 May 2018

Genetic fixer-uppers could aid in predicting prognosis of patients with bladder cancer

Mutations in genes that help repair damage to DNA may aid in predicting the prognosis of patients with bladder and other related cancers, according to researchers.

15 May 2018

Phase 1/2 study evaluates safety, tolerability of multiple-ascending doses of ARO-HBV in hepatitis B patients

Arrowhead Pharmaceuticals Inc. today announced that it has dosed the first 3 hepatitis B virus patients in the multiple-ascending dose portion of its ongoing Phase 1/2 study of ARO-HBV, the company's third generation subcutaneously administered RNA interference therapeutic being developed as a potentially curative therapy for patients with chronic HBV infection.

14 May 2018

LogicBio team to present data on preclinical effectiveness of GeneRide platform

LogicBio Therapeutics, Inc., a genetic medicine company founded to develop safe medicines with lasting therapeutic benefit for children with life-threatening diseases, today announced it will be presenting data on the company's technology and robust preclinical pipeline at the annual meeting of the American Society of Gene & Cell Therapy at the Hilton Chicago, from May 16-19, 2018.

14 May 2018

Havard University grants license to Beam Therapeutics to develop new base editing technology

Harvard University has granted a worldwide license to Beam Therapeutics, Inc., to develop and commercialize a suite of revolutionary DNA base editing technologies for the treatment of human disease.

14 May 2018

Oxford University Press and Chinese Antibody Society partner to launch Antibody Therapeutics

Oxford University Press and the Chinese Antibody Society are pleased to announce their new partnership to launch the journal Antibody Therapeutics this spring.

9 May 2018

Akili Interactive closes $55 million financing to advance digital medicine platform for treatment of cognitive dysfunction

Akili Interactive, a leading prescription digital medicine company developing novel treatments for cognitive dysfunction, today announced that it has successfully closed a $55 million Series C financing led by Temasek.

9 May 2018

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Neon Therapeutics, a clinical-stage immuno-oncology company developing neoantigen-based therapeutics, today announced that it has treated the first patient in a clinical trial evaluating its proprietary personal neoantigen vaccine, NEO-PV-01, in combination with Merck's anti-PD-1 therapy, KEYTRUDA®, along with chemotherapy.

8 May 2018

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Company has achieved delivery of novel small interfering RNA conjugates to the central nervous system and is planning to advance a pipeline of investigational RNAi therapeutics into clinical development.

8 May 2018

Novel 3D cancer model to accelerate development of new and better treatments

A scientist at the University of Virginia School of Medicine, working with local biotech company HemoShear Therapeutics, has created a three-dimensional model of a cancer tumor that he says has the potential to replicate the complex nature and behavior of a real tumor.

7 May 2018

Researchers discover how key brain receptor can function in hostile environment

During a stroke or an epileptic seizure, neurons in affected parts of the brain fire at an abnormally rapid rate.

7 May 2018

NucleoBio's new test kit could accurately reveal results of prostate cancer screening

Recognizing that prostate cancer in men is misdiagnosed, NucleoBio Inc. is developing a new product, Prostac, that will accurately reveal results of a prostate cancer screening.

4 May 2018

Osteoporosis drug prevents spread of basal-like breast cancer in mice

Researchers in China have discovered that an enzyme called UGT8 drives the progression of basal-like breast cancer, an aggressive form of the disease that is largely untreatable.

4 May 2018

Sylentis presents clinical study results of new treatment for dry eye syndrome

Sylentis, Pharmaceutical Company belonging to the PharmaMar Group, has presented results from the clinical studies carried out with tivanisiran for the treatment of dry eye syndrome and that has enabled the start-up of the Phase III "Helix" clinical trial.

3 May 2018

Cancer Center at BIDMC announces launch of new Immunotherapy Institute

The Cancer Center at Beth Israel Deaconess Medical Center today announced the launch of a new clinical and research institute that will build on BIDMC's long history of leadership in immunotherapy and cell therapeutics.

3 May 2018

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics.

3 May 2018

Moving beyond traditional 'magic bullet' approach for discovering new drugs

It's time to move beyond the traditional 'magic bullet' approach for discovering new drugs and start leveraging the full complexity of Mother Nature, say Vanderbilt Professor of Chemistry Brian Bachmann and Assistant Professor of Cell and Developmental Biology Jonathan Irish.

3 May 2018

New mosquito automated liquid handling system hastens research into protein-based therapeutics

AXT have recently completed the installation of an automated liquid handling system at the Victoria University of Wellington in New Zealand.

From SPT Labtech 2 May 2018

Gene therapy offers potential cure for patients with lipoprotein lipase deficiency

During the first 18 months after treatment with ali-pogene tiparvovec, a gene therapy recently approved in Europe to treat lipoprotein lipase deficiency (LPLD), the first patient to receive the treatment had no abdominal pain or episodes of pancreatitis, following a history of 37 pancreatitis attacks.

2 May 2018

New GP-write project to develop ultra-safe cells resistant to natural viruses

The Center for Excellence in Engineering Biology and the leadership of Genome Project-write today announced its first grand-scale community-wide project, to develop "ultra-safe cells" that resist natural viruses and potentially radiation, freezing, aging and cancer.

2 May 2018

Therapeutics News and Research

Opioid pharmaceutical marketing influences physicians' opioid prescribing rates

Genetic fixer-uppers could aid in predicting prognosis of patients with bladder cancer

Phase 1/2 study evaluates safety, tolerability of multiple-ascending doses of ARO-HBV in hepatitis B patients

LogicBio team to present data on preclinical effectiveness of GeneRide platform

Havard University grants license to Beam Therapeutics to develop new base editing technology

Oxford University Press and Chinese Antibody Society partner to launch Antibody Therapeutics

Akili Interactive closes $55 million financing to advance digital medicine platform for treatment of cognitive dysfunction

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Novel 3D cancer model to accelerate development of new and better treatments

Researchers discover how key brain receptor can function in hostile environment

NucleoBio's new test kit could accurately reveal results of prostate cancer screening

Osteoporosis drug prevents spread of basal-like breast cancer in mice

Sylentis presents clinical study results of new treatment for dry eye syndrome

Cancer Center at BIDMC announces launch of new Immunotherapy Institute

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

Moving beyond traditional 'magic bullet' approach for discovering new drugs

New mosquito automated liquid handling system hastens research into protein-based therapeutics

Gene therapy offers potential cure for patients with lipoprotein lipase deficiency

New GP-write project to develop ultra-safe cells resistant to natural viruses

Industry Focus eBook - Microbiome (1st edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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