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Simple trick supercharges T cells to fight stubborn solid tumors

Wistar researchers successfully tested a simple intervention that could unlock greater anti-tumor power in therapies that use T cells - an approach known as "cell-based therapy," which uses specially designed T cells to fight cancer.

13 Dec 2023

Targeting cholesterol metabolism for the treatment of serrated colorectal neoplasms

Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a preclinical study from researchers at Weill Cornell Medicine.

13 Dec 2023

$153,000 grant fuels research on new approaches to inhibit STAT3 and develop novel cancer treatments

With an estimated 1.9 million new cases and more than 600,000 deaths each year, cancer remains the second most common cause of death in the U.S., trailing only heart disease. And while there are more than 200 types of cancer, the abnormal synthesis of a protein known as STAT3 is unique to the majority of tumors.

13 Dec 2023

Developing a virtual twin for personalized cancer treatment with CAR-T cell therapy

In recent years, cancer immunotherapies have established themselves as a further pillar of medical oncology alongside traditional treatment options (surgery, radiotherapy and chemotherapy).

13 Dec 2023

Understanding why cutting-edge cell therapies cause an increased risk of heart rhythm disorders

A type of cell that plays a crucial role in tissue repair after a heart attack may also inadvertently be why cutting-edge cell therapies cause an increased risk of rhythm disorders, according to a new study from the Universities of Surrey and Oxford.

13 Dec 2023

Glycan analysis holds promise for early diagnosis of various cancers

In the future, a little saliva may be enough to detect an incipient cancer. Researchers at the University of Gothenburg have developed an effective way to interpret the changes in sugar molecules that occur in cancer cells.

13 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

OHSU study sheds light on ubiquitin modification during bacterial infection

New research from Oregon Health & Science University could one day lead to therapies that prevent or treat diseases and infections tied to a protein that's found in all human cells.

12 Dec 2023

Stem cell therapy trial shows promise for regenerative treatment of heart failure

Stem cell-based therapy improved quality of life for patients with advanced heart failure, Mayo Clinic researchers and international collaborators discovered in a late-stage multinational clinical trial.

12 Dec 2023

Researchers find powerful combo weapon against aggressive lymphoma

The targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (PFS) and achieved an overall remission rate in 82% of patients with relapsed/refractory mantle cell lymphoma (MCL), according to researchers at The University of Texas MD Anderson Cancer Center. Results from the Phase III SYMPATICO trial were presented at the 2023 American Society of Hematology (ASH) Annual Meeting.

12 Dec 2023

Brainoware: A breakthrough AI approach using brain organoids for advanced computation

Study in Nature Electronics introduces "Brainoware," an innovative AI hardware approach using brain organoid neural networks for complex tasks like speech recognition and nonlinear dynamic predictions, demonstrating significant potential in AI development.

12 Dec 2023

Liquid biopsy may offer new tools for personalized immunotherapy in lung cancer

Using a "liquid biopsy" to study genetic material from tumors shed into the bloodstream together with immune cells could help clinicians predict which patients with advanced lung cancers are responding to immunotherapies and which patients may develop immune-related side effects several months later, according to research directed by investigators at the Johns Hopkins Kimmel Cancer Center, the Bloomberg~Kimmel Institute for Cancer Immunotherapy and Allegheny Health Network Cancer Institute in Pittsburgh.

12 Dec 2023

Daily consumption of prunes may reduce inflammation markers and bone loss effects

A new study published in The Journal of Nutrition shows daily consumption of prunes may reduce inflammation markers connected to bone signaling pathways and reduce the effects of bone loss among postmenopausal women.

12 Dec 2023

Study unlocks protein clues to aggressive lymphoma transformation

Researchers have come one step closer to answering why, in some patients, a type of lymphoma changes from indolent to aggressive, and in particular they are closer to identifying which patients are at high risk of this change happening.

12 Dec 2023

UVA atlas unveils cellular blueprint of atherosclerosis

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes and coronary artery disease.

12 Dec 2023

B Cell News and Research

Simple trick supercharges T cells to fight stubborn solid tumors

Targeting cholesterol metabolism for the treatment of serrated colorectal neoplasms

$153,000 grant fuels research on new approaches to inhibit STAT3 and develop novel cancer treatments

Developing a virtual twin for personalized cancer treatment with CAR-T cell therapy

Understanding why cutting-edge cell therapies cause an increased risk of heart rhythm disorders

Glycan analysis holds promise for early diagnosis of various cancers

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

OHSU study sheds light on ubiquitin modification during bacterial infection

Stem cell therapy trial shows promise for regenerative treatment of heart failure

Researchers find powerful combo weapon against aggressive lymphoma

Brainoware: A breakthrough AI approach using brain organoids for advanced computation

Liquid biopsy may offer new tools for personalized immunotherapy in lung cancer

Daily consumption of prunes may reduce inflammation markers and bone loss effects

Study unlocks protein clues to aggressive lymphoma transformation

UVA atlas unveils cellular blueprint of atherosclerosis

New study unlocks hope for immunotherapy in metastatic prostate cancer

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

New optimized vaccine approach targets Hepatitis C virus variability

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Revolutionizing diabetes care: tPBM therapy proves effective in restoring microglial health

Using single B cell screening to boost antibody discovery eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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