Clinical Trial News and Research

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Adding targeted therapy drug to standard treatment benefits aggressive breast cancer patients

A study led by UCLA researchers found that adding ribociclib, a targeted therapy drug, to standard hormone therapy has been shown to significantly improve overall survival in postmenopausal women with advanced hormone-receptor positive/HER2- breast cancer, one of the most common forms of the disease.

29 Sep 2019

Additional heart artery stenting can help prevent future heart attacks

Research has shown that patients who have had emergency heart attack treatment with heart artery stenting - and have significant narrowings in their other untreated arteries - can benefit from additional stenting to help prevent future heart attacks.

28 Sep 2019

Novel therapeutic approach improves survival in patients newly diagnosed with advanced ovarian cancer

An international study demonstrates that administering niraparib after conventional chemotherapy treatment in patients newly diagnosed with advanced ovarian cancer, improves their progression-free survival, and reduces their risk of relapse or death from this disease.

28 Sep 2019

PARP inhibitor combined with chemotherapy increases survival for newly diagnosed ovarian cancer patients

Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that initial treatment with the PARP inhibitor veliparib in combination with chemotherapy significantly increased progression-free survival for patients with newly diagnosed, metastatic high-grade serous ovarian cancer, according to the results of the VELIA trial.

28 Sep 2019

Study: Nearly half of cancer patients who enter a tobacco treatment program quit smoking

In the largest smoking cessation study of cancer patients to date, researchers from The University of Texas MD Anderson Cancer Center found that comprehensive tobacco treatment can help cancer patients successfully quit and abstain from smoking.

27 Sep 2019

Tobacco treatment program in an oncologic setting could foster smoking cessation

A tobacco treatment program delivered at a cancer center had average seven-day smoking abstinence rates of about 45% at three- and six-month follow-ups and nearly 44% at the nine-month follow-up, and those rates didn't differ between patients with and without cancer.

27 Sep 2019

High-risk heart patients may not require long-term aspirin use after stent placement

High-risk patients undergoing coronary stent procedures may not require long-term aspirin use after stent placement, Mount Sinai researchers report in a groundbreaking study

26 Sep 2019

Children's of Alabama using cold sore virus to fight pediatric brain cancer

Children's of Alabama is home to one of the most exciting studies underway in pediatric cancer: evaluating the use of a cold sore virus to treat children with progressive malignant brain tumors.

26 Sep 2019

Partial, whole breast radiation after lumpectomy yield similar cosmetic outcomes

Whole breast radiation and partial breast radiation following a lumpectomy yield similar cosmetic outcomes for women diagnosed with early stages of cancer who wish to preserve their breasts.

26 Sep 2019

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

An international, multicenter phase II clinical trial is evaluating the efficacy and safety of mavrilimumab co-administered with a 26-week corticosteroid taper in patients with giant cell arteritis.

26 Sep 2019

High-dose radiation effective for men whose prostate cancer has spread, trial shows

A randomized clinical trial of targeted, high-dose radiation for men with oligometastatic prostate cancer has shown the treatment to be an effective and safe option for patients who wish to delay hormone-suppression therapy.

26 Sep 2019

Long-term hormone therapy does more harm than good for men with low PSAs after prostate surgery

A secondary analysis of a recent clinical trial that changed the standard of care for men with recurring prostate cancer finds long-term hormone therapy does more harm than good for many men and calls for rethinking treatment guidelines based on a patient's post-operative prostate-specific antigen (PSA) level.

26 Sep 2019

Late-breaking TAILORx data to be presented at ESMO Congress 2019

New data from TAILORx, the federally funded, phase three clinical trial, will be presented as late-breaking information at the European Society for Medical Oncology (ESMO) 2019 Congress in Barcelona, Spain.

26 Sep 2019

Study into skin collection of blood chemistry from babies aims to replace invasive blood tests

Scientists at the University of Strathclyde are researching a system to measure and monitor blood chemistry levels in premature and sick babies through their skin, which if successful, could eventually replace the need for invasive blood tests.

25 Sep 2019

Scientists use new single-cell genetic technique to tackle potential drug resistance

Using a new technique that can identify genetic profiles of individual cells, University of Notre Dame researchers modeled a breast cancer tumor's potential resistance to a drug, and then identified a drug combination that reversed that resistance.

25 Sep 2019

Experimental treatment shows early promise to help nearly half of DMD patients

A new therapeutic being tested by University of Alberta researchers is showing early promise as a more effective treatment that could help nearly half of patients with Duchenne muscular dystrophy.

25 Sep 2019

Metabolic imbalance in cancer patients associated with resistance to immune checkpoint blocker

A metabolic imbalance in some cancer patients following treatment with a checkpoint inhibitor drug, nivolumab, is associated with resistance to the immunotherapy agent and shorter survival, report scientists from Dana-Farber Cancer Institute, in collaborative work with the Broad Institute of MIT and Harvard.

25 Sep 2019

New review provides knowledge about sex-related differences in Parkinson's disease

There is growing evidence that Parkinson's disease affects women and men differently. In this insightful review, published in the Journal of Parkinson's Disease, scientists present the most recent knowledge about these sex-related differences and highlight the significance of estrogens, which play an important role in the sex differences in PD.

25 Sep 2019

Study identifies factor essential for tendon growth

Insulin-like growth factor 1 (IGF1) is essential for allowing tendons to adapt to physical activity and grow properly, according to basic science research by investigators at Hospital for Special Surgery.

24 Sep 2019

Cryoablation procedure could be an alternative to surgery for breast cancer

When Jeanne Anderson was diagnosed with breast cancer three years ago, the Beverly Hills resident underwent a course of chemotherapy to shrink the tumors in preparation for surgery.

24 Sep 2019

Clinical Trial News and Research

Adding targeted therapy drug to standard treatment benefits aggressive breast cancer patients

Additional heart artery stenting can help prevent future heart attacks

Novel therapeutic approach improves survival in patients newly diagnosed with advanced ovarian cancer

PARP inhibitor combined with chemotherapy increases survival for newly diagnosed ovarian cancer patients

Study: Nearly half of cancer patients who enter a tobacco treatment program quit smoking

Tobacco treatment program in an oncologic setting could foster smoking cessation

High-risk heart patients may not require long-term aspirin use after stent placement

Children's of Alabama using cold sore virus to fight pediatric brain cancer

Partial, whole breast radiation after lumpectomy yield similar cosmetic outcomes

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

High-dose radiation effective for men whose prostate cancer has spread, trial shows

Long-term hormone therapy does more harm than good for men with low PSAs after prostate surgery

Late-breaking TAILORx data to be presented at ESMO Congress 2019

Study into skin collection of blood chemistry from babies aims to replace invasive blood tests

Scientists use new single-cell genetic technique to tackle potential drug resistance

Experimental treatment shows early promise to help nearly half of DMD patients

Metabolic imbalance in cancer patients associated with resistance to immune checkpoint blocker

New review provides knowledge about sex-related differences in Parkinson's disease

Study identifies factor essential for tendon growth

Cryoablation procedure could be an alternative to surgery for breast cancer

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