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Scientists disrupt two enzymes to shrink cancer cells

Before cell division, the long strings of the cell's DNA are wrapped tightly into the structures we know as chromosomes. This protects the cell's genetic material from physical and chemical damage.

17 May 2018

New study reveals the extent of brain damage due to elevated homocysteine

The amino acid homocysteine occurs naturally in the human body, generated as a byproduct of methionine metabolism.

17 May 2018

HKBU researchers develop metal based probes for imaging dopamine receptors in living cells

A team led by Dr Edmond Ma Dik-lung, Associate Professor of the Department of Chemistry of Hong Kong Baptist University has developed the world's first iridium(III)-based probes for imaging dopamine receptors in living cells.

16 May 2018

Researchers demonstrate new strategy for stimulating autophagy

Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.

16 May 2018

Scientists find fast way to manipulate cell's cilia

Scientists at Johns Hopkins Medicine and the National Tsing Hua University in Taiwan say they have found a fast way to manipulate a cell's cilia, the tiny, fingerlike protrusions that "feel" and sense their microscopic environment.

16 May 2018

Interfering with enzyme's movement may be new approach for developing of anti-cancer drugs

Revealing all the steps required to activate an enzyme called a protein kinase may identify new ways to target cancer, according to new University of Arizona-led research.

16 May 2018

Biochemists isolate protein supercomplex from bacteria that generates voltage

Biochemists at the University of Illinois have isolated a protein supercomplex from a bacterial membrane that, like a battery, generates a voltage across the bacterial membrane.

15 May 2018

Familial Chylomicronemia Syndrome: How HCP’s can Support Patients with Rare Diseases

Dr Robert Cramb gives an introduction to the rare disease FCS, and how HCP's can best advise and support patients with the condition.

15 May 2018

Scientists identify key factor that clears the way for gene activation

Until human genes are activated, they are blocked by structures known as nucleosomes, components that serve to package DNA inside cells.

15 May 2018

Researchers reverse Alzheimer's symptoms in flies by restoring epigenetic balance

Researchers from Drexel University reversed symptoms of Alzheimer's disease in fruit flies by restoring the balance between two epigenetic enzymes that regulate gene expression, a study shows.

15 May 2018

FDA approves new drug to treat MS in pediatric patients

The U.S. Food and Drug Administration today approved Gilenya (fingolimod) to treat relapsing multiple sclerosis (MS) in children and adolescents age 10 years and older. This is the first FDA approval of a drug to treat MS in pediatric patients.

14 May 2018

New studies use proteomics to shed light on pathogenic mechanisms

Recent studies in the journal Molecular & Cellular Proteomics have shed light on pathogenic mechanisms of the sexually-transmitted parasite Trichomonas vaginalis and the HIV-associated opportunistic lung fungus Aspergillus.

11 May 2018

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Kidney cancer, one of the ten most prevalent malignancies in the world, has increased in incidence over the last decade, likely due to rising obesity rates.

10 May 2018

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

A new and early target for treating pulmonary hypertension appears to be an enzyme that's normally key to energy production but destructive in the face of this high blood pressure inside your lungs.

8 May 2018

Research shows possibility of new ways to address blood-brain barrier dysfunction in epilepsy

New findings from the University of Kentucky published in the Journal of Neuroscience demonstrate that there may be ways to address blood-brain barrier dysfunction in epilepsy.

8 May 2018

Researchers uncover novel approach for treating neuropathic pain

Neuropathic pain is the chronic, pathological pain that continues even when the cause of pain is removed. Causes include damage to nerve cells and medicines used to treat cancer.

4 May 2018

Osteoporosis drug prevents spread of basal-like breast cancer in mice

Researchers in China have discovered that an enzyme called UGT8 drives the progression of basal-like breast cancer, an aggressive form of the disease that is largely untreatable.

4 May 2018

UCLA researchers report promising drug strategy to block tau transmission

Alzheimer's disease destroys brain cells in part by promoting the formation of insoluble clumps that contain a protein called tau.

3 May 2018

Researchers discover glutamine-dependent activation of cell growth and autophagy

The human body consists of about 35 trillion cells, so it could be said that overall body growth is the growth of individual cells.

3 May 2018

Study: HCV-exposed infants not adequately screened, despite increased prevalence

Due to the opioid epidemic, hepatitis C virus is increasing among pregnant women, resulting in a greater risk of perinatal transmission and HCV infection among children.

2 May 2018