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NRAS gene that plays fundamental role in cancer development produces five gene variants, says study

A new study shows that a gene discovered 30 years ago and now known to play a fundamental role in cancer development produces five different gene variants (called isoforms), rather than just the one original form, as thought.

8 Apr 2014

Genome Project offers new leads to improve outcomes for children with high-grade glioma brain tumors

The St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project has identified new mutations in pediatric brain tumors known as high-grade gliomas (HGGs), which most often occur in the youngest patients.

8 Apr 2014

Findings could lead to more potent anti-diabetic drugs with fewer side effects

Scientists thought they basically knew how the most common drugs used to treat type 2 diabetes worked, but a new study from the Florida campus of The Scripps Research Institute (TSRI) reveals unexpected new aspects of the process. These findings could eventually lead to more potent anti-diabetic drugs with fewer serious side effects.

7 Apr 2014

UPCI/MWRI researchers to present results of immune gene profile exploring endometriosis and cancer

Some women with endometriosis, a chronic inflammatory disease, are predisposed to ovarian cancer, and a genetic screening might someday help reveal which women are most at risk, according to a University of Pittsburgh Cancer Institute (UPCI) study, in partnership with Magee-Womens Research Institute (MWRI).

7 Apr 2014

Caffeine has positive effect on tau deposits in Alzheimer's disease

As part of a German-French research project, a team led by Dr. Christa E. Müller from the University of Bonn and Dr. David Blum from the University of Lille was able to demonstrate for the first time that caffeine has a positive effect on tau deposits in Alzheimer's disease.

7 Apr 2014

TSRI scientists solve long-standing mystery about sense of touch

A study led by scientists at The Scripps Research Institute (TSRI) has helped solve a long-standing mystery about the sense of touch.

7 Apr 2014

New insights provide novel therapeutic approach against cancer

A major discovery that brings a new drug target to the increasingly exciting landscape of cancer immunotherapy was published yesterday by researchers from La Jolla Institute for Allergy and Immunology and their collaborators from other institutes.

7 Apr 2014

Compounds from plant confer protective effects against breast cancer, say researchers

Compounds derived from plant-based sources - including garlic, broccoli and medicine plants - confer protective effects against breast cancer, explain researchers at the University of Pittsburgh Cancer Institute (UPCI), partner with the UPMC CancerCenter.

7 Apr 2014

Deciphera Pharmaceuticals initiates Phase 1 clinical trial of pan-RAF inhibitor LY3009120

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7 Apr 2014

Research suggests NEDD9 scaffolding protein activates oncogenic signaling pathways in cancer cells, encourages metastases

Researchers from Fox Chase Cancer Center have shown that NEDD9, a scaffolding protein responsible for regulating signaling pathways in the cell, promotes the growth and spread of epithelial ovarian cancer.

7 Apr 2014

Wistar findings suggest link between colon microbiome and genome stability

Colorectal cancer develops in what is probably the most complex environment in the human body, a place where human cells cohabitate with a colony of approximately 10 trillion bacteria, most of which are unknown.

7 Apr 2014

Researchers discover hotspot L205R mutation is closely associated with adrenocortical tumors

Chinese researchers from Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, BGI, and other institutions have discovered that the activating hotspot L205R mutation in PRKACA gene was closely associated with adrenocortical tumors (ACTs), and the relationship of recurrently mutated DOT1L and CLASP2 with ACTs' other subtypes.

7 Apr 2014

Researchers demonstrate accurate identification of amino acids

Some three billion base pairs make up the human genome-the floor plan of life. In 2003, the Human Genome Project announced the successful decryption of this code, a tour de force that continues to supply a stream of insights relevant to human health and disease.

7 Apr 2014

Food quality may drop due to elevated levels of atmospheric carbon dioxide, shows field study

For the first time, a field test has demonstrated that elevated levels of carbon dioxide inhibit plants' assimilation of nitrate into proteins, indicating that the nutritional quality of food crops is at risk as climate change intensifies.

7 Apr 2014

$Study investigates link between bone microstructure in postmenopausal women and prevalent ankle fracture$

Study investigates link between bone microstructure in postmenopausal women and prevalent ankle fracture

A study by researchers at the University of Geneva concludes that prevalent ankle fractures should be considered as osteoporotic fractures and taken into account in fracture-risk assessment.

7 Apr 2014

Too little or too much of SRPK1 enzyme promotes cancer, shows research

Researchers at the University of California, San Diego School of Medicine have found that too little or too much of an enzyme called SRPK1 promotes cancer by disrupting a regulatory event critical for many fundamental cellular processes, including proliferation.

4 Apr 2014

Novartis to present early stage data on 19 investigational compounds at AACR annual meeting

Novartis announced today that early stage data on 19 investigational compounds in its oncology pipeline will be presented at the annual meeting of the American Association of Cancer Research, April 5-9, 2014 in San Diego, CA.

4 Apr 2014

Deutsche Forschungsgemeinschaft to establish 5 new Research Units

Topics Range from Composite Structures to Personnel Decisions to Metastatic Cancer Progression / About Eleven Million Euros in Funding for Three Years

4 Apr 2014

High levels of protein intake and exercise improve bone structure, strength in pre-pubertal boys

A study presented during the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases in Seville shows that high levels of protein intake (HProt) enhance the positive impact of high physical activity (HPA) on bone structure and strength in healthy pre-pubertal boys. Researchers from the University of Geneva in Switzerland and Eindhoven University in the Netherlands tracked 176 healthy pre-pubertal boy

4 Apr 2014

Neuroinflammation levels higher in patients with chronic fatigue syndrome

Researchers at the RIKEN Center for Life Science Technologies, in collaboration with Osaka City University and Kansai University of Welfare Sciences, have used functional PET imaging to show that levels of neuroinflammation, or inflammation of the nervous system, are higher in patients with chronic fatigue syndrome than in healthy people.

4 Apr 2014

G Protein News and Research

NRAS gene that plays fundamental role in cancer development produces five gene variants, says study

Genome Project offers new leads to improve outcomes for children with high-grade glioma brain tumors

Findings could lead to more potent anti-diabetic drugs with fewer side effects

UPCI/MWRI researchers to present results of immune gene profile exploring endometriosis and cancer

Caffeine has positive effect on tau deposits in Alzheimer's disease

TSRI scientists solve long-standing mystery about sense of touch

New insights provide novel therapeutic approach against cancer

Compounds from plant confer protective effects against breast cancer, say researchers

Deciphera Pharmaceuticals initiates Phase 1 clinical trial of pan-RAF inhibitor LY3009120

Research suggests NEDD9 scaffolding protein activates oncogenic signaling pathways in cancer cells, encourages metastases

Wistar findings suggest link between colon microbiome and genome stability

Researchers discover hotspot L205R mutation is closely associated with adrenocortical tumors

Researchers demonstrate accurate identification of amino acids

Food quality may drop due to elevated levels of atmospheric carbon dioxide, shows field study

Study investigates link between bone microstructure in postmenopausal women and prevalent ankle fracture

Too little or too much of SRPK1 enzyme promotes cancer, shows research

Novartis to present early stage data on 19 investigational compounds at AACR annual meeting

Deutsche Forschungsgemeinschaft to establish 5 new Research Units

High levels of protein intake and exercise improve bone structure, strength in pre-pubertal boys

Neuroinflammation levels higher in patients with chronic fatigue syndrome

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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